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GPR19 (G Protein-Coupled Receptor 19) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is TACR2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004930 | G protein-coupled receptor activity | TAS,IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | IEA | -- |
GO:0005887 | integral component of plasma membrane | TAS | 8830667 |
GO:0005929 | cilium | IDA | 28154160 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Peptide ligand-binding receptors |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007165 | signal transduction | IEA | -- |
GO:0007186 | G protein-coupled receptor signaling pathway | TAS,IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | GPR19 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | GPR19 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | GPR19 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Gpr19 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Gpr19 30 17 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | GPR19 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | GPR19 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | gpr19 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | gpr19 30 31 |
|
OneToOne | |
zgc63912 30 |
|
||||
Fruit Fly (Drosophila melanogaster) |
Insecta | TrissinR 31 |
|
ManyToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | npr-10 31 |
|
OneToMany | |
npr-3 31 |
|
OneToMany | |||
npr-7 31 |
|
OneToMany | |||
npr-2 31 |
|
OneToMany | |||
npr-1 31 |
|
OneToMany | |||
npr-5 31 |
|
OneToMany | |||
npr-4 31 |
|
OneToMany | |||
npr-13 31 |
|
OneToMany | |||
npr-8 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
695291 | Benign: not provided | 12,717,002(-) | C/A | ||
713760 | Benign: not provided | 12,661,947(-) | C/T | MISSENSE_VARIANT | |
723538 | Benign: not provided | 12,661,285(-) | C/T | SYNONYMOUS_VARIANT | |
781064 | Benign: not provided | 12,662,044(-) | A/G | SYNONYMOUS_VARIANT | |
827022 | Uncertain Significance: Multiple endocrine neoplasia, type 4; Hereditary cancer-predisposing syndrome | 12,717,767(-) | G/A | FIVE_PRIME_UTR_VARIANT |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv89n21 | CNV | gain | 19592680 |
esv2745567 | CNV | deletion | 23290073 |
nsv1046355 | CNV | loss | 25217958 |
nsv509456 | CNV | insertion | 20534489 |
nsv983287 | CNV | duplication | 23825009 |
No disorders were found for GPR19 Gene.