Aliases for GPR19 Gene
Aliases for GPR19 Gene
External Ids for GPR19 Gene
- HGNC: 4473
- Entrez Gene: 2842
- Ensembl: ENSG00000183150
- OMIM: 602927
- UniProtKB: Q15760
Previous GeneCards Identifiers for GPR19 Gene
- GC12M012541
- GC12M012958
- GC12M012714
- GC12M012813
Summaries for GPR19 Gene
GeneCards Summary for GPR19 Gene
GPR19 (G Protein-Coupled Receptor 19) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is AVPR1A.
UniProtKB/Swiss-Prot for GPR19 Gene
-
Orphan receptor.
Additional gene information for GPR19 Gene
- Monarch Initiative
- Search for GPR19 at DataMed
- Search for GPR19 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPR19 Gene
Genomics for GPR19 Gene
GeneHancer (GH) Regulatory Elements for GPR19 Gene
Promoters and enhancers for GPR19 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around GPR19 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the GPR19 gene promoter:
-
- AP-1
- MyoD
- FOXO1a
- FOXO1
- GATA-1
- c-Jun
- ATF-2
- FOXO4
- AREB6
Regulatory Element Products
Genomic Locations for GPR19 Gene
Genomic Locations for GPR19 Gene
- chr12:12,660,884-12,717,272
- (GRCh38/hg38)
- Size:
- 56,389 bases
- Orientation:
- Minus strand
- chr12:12,813,825-12,849,141
- (GRCh37/hg19)
- Size:
- 35,317 bases
- Orientation:
- Minus strand
Genomic View for GPR19 Gene
Genes around GPR19 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p13.1 by Entrez Gene
- 12p13.1 by HGNC
- 12p13.1 by Ensembl
GPR19 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GPR19 Gene
Proteins for GPR19 Gene
-
Protein details for GPR19 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q15760-GPR19_HUMAN
- Recommended name:
- Probable G-protein coupled receptor 19
- Protein Accession:
- Q15760
Protein attributes for GPR19 Gene
- Size:
- 415 amino acids
- Molecular mass:
- 47687 Da
- Quaternary structure:
- No Data Available
Protein Expression for GPR19 Gene
Post-translational modifications for GPR19 Gene
Other Protein References for GPR19 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for GPR19
- Novus Biologicals Antibodies for GPR19
-
Abcam antibodies for GPR19
- Invitrogen Antibodies for GPR19 (AFLGC-GPR19)
- GeneTex GPR19 Antibody for GPR19
-
Boster Bio Antibodies for GPR19
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for GPR19
- Origene Custom Protein Services for GPR19
- Novus Biologicals proteins for GPR19
- Search GeneTex for Proteins for GPR19
-
Abcam proteins for GPR19
Assay Products
No data available for DME Specific Peptides for GPR19 Gene
Domains & Families for GPR19 Gene
Gene Families for GPR19 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- G-protein coupled receptors
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for GPR19 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for GPR19 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q15760- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for GPR19 Gene
Molecular function for GPR19 Gene
- UniProtKB/Swiss-Prot Function:
- Orphan receptor.
- GENATLAS Biochemistry:
- G protein coupled receptor 19,with strong homology with D2 dopamine and adregenic receptors,expressed in caudate nucleus,putamen and thalamus,involved in cancer cells
Phenotypes From GWAS Catalog for GPR19 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | TAS,IEA | -- |
Phenotypes for GPR19 Gene
- MGI mutant phenotypes for GPR19:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for GPR19:
-
- Decreased viability ratio
- Decreased shRNA abundance (Z-score < -2)
- Effect on mitosis
- Dynamic nuclei (hole, folded or small irregular)
- Increased shRNA abundance (Z-score > 2)
- Decreased homologous recombination repair frequency
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Decreased NF-kappaB reporter expression
- shRNA abundance <= 50%
- Decreased IL-8 secretion
Animal Models for GPR19 Gene
- MGI Knock Outs for GPR19:
-
- Gpr19 Gpr19<tm1Dgen>
Animal Model Products
-
Taconic Biosciences Mouse Models for GPR19
- Cyagen custom Knockout/knockin (KOKI) mouse models for GPR19
-
CRISPR Products
-
OriGene CRISPR knockouts for GPR19
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GPR19
- genomics-online: gRNA clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Applied Biological Materials CRISPR for GPR19
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for GPR19
- GenScript: Design CRISPR guide RNA sequences for GPR19
miRNA for GPR19 Gene
- miRTarBase miRNAs that target GPR19
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GPR19
- Browse OriGene Inhibitory RNA Products For GPR19
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GPR19
- genomics-online: shRNA clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Clone Products
- Sino Biological Human cDNA Clone for GPR19
- Addgene plasmids for GPR19
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GPR19
- genomics-online: cdna clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- orf clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Applied Biological Materials Clones for GPR19
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for GPR19
Cell Line Products
-
Horizon Cell Lines for GPR19
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GPR19 Gene
Localization for GPR19 Gene
Subcellular locations from UniProtKB/Swiss-Prot for GPR19 Gene
- Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0005887 | integral component of plasma membrane | TAS | 8830667 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for GPR19 Gene
Pathways & Interactions for GPR19 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Peptide ligand-binding receptors | ||
Pathways by source for GPR19 Gene
1 BioSystems pathway for GPR19 Gene
Interacting Proteins for GPR19 Gene
GPS-Prot Interaction Network for GPR19
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | 8830667 |
| GO:0007218 | neuropeptide signaling pathway | IBA | -- |
| GO:0007268 | chemical synaptic transmission | IBA | -- |
| GO:0007631 | feeding behavior | IBA | -- |
No data available for SIGNOR curated interactions for GPR19 Gene
Transcripts for GPR19 Gene
mRNA/cDNA for GPR19 Gene
- (8) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (15) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000540510 1751 bps (uc001rar.4)
- ENST00000540796 553 bps (uc058lir.1)
- ENST00000545876 585 bps (uc058lit.1)
- ENST00000537507 706 bps (uc058liu.1)
- ENST00000332427 1743 bps (uc001raq.2)
Unigene Clusters for GPR19 Gene
CRISPR Products
-
OriGene CRISPR knockouts for GPR19
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GPR19
- genomics-online: gRNA clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Applied Biological Materials CRISPR for GPR19
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for GPR19
- GenScript: Design CRISPR guide RNA sequences for GPR19
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GPR19
- Browse OriGene Inhibitory RNA Products For GPR19
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GPR19
- genomics-online: shRNA clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Clone Products
- Sino Biological Human cDNA Clone for GPR19
- Addgene plasmids for GPR19
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GPR19
- genomics-online: cdna clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- orf clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Applied Biological Materials Clones for GPR19
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for GPR19
Expression for GPR19 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
- NULL (Uncategorized)
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for GPR19 Gene
This gene is overexpressed in Pituitary (x4.8), Brain - Nucleus accumbens (basal ganglia) (x4.2), and Brain - Cerebellar Hemisphere (x4.1).
This gene is overexpressed in Saliva (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GPR19 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of GPR19 Gene:
GPR19SOURCE GeneReport for Unigene cluster for GPR19 Gene:
Hs.657862mRNA Expression by UniProt/SwissProt for GPR19 Gene:
Q15760-GPR19_HUMAN
Tissue specificity:
Abundant expression in the brain.
Primer Products
-
OriGene qPCR primer pairs for GPR19
-
OriGene qPCR primer pairs and template standards for GPR19
- genomics-online: primer clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Gene Expression Assay Products
No data available for Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GPR19 Gene
Orthologs for GPR19 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | GPR19 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | GPR19 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | GPR19 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Gpr19 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Gpr19 16 34 33 |
|
||
| chicken (Gallus gallus) |
Aves | GPR19 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | GPR19 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | gpr19 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | gpr19 34 33 |
|
OneToOne | |
| zgc63912 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | TrissinR 34 |
|
ManyToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | npr-10 34 |
|
OneToMany | |
| npr-3 34 |
|
OneToMany | |||
| npr-7 34 |
|
OneToMany | |||
| npr-2 34 |
|
OneToMany | |||
| npr-1 34 |
|
OneToMany | |||
| npr-5 34 |
|
OneToMany | |||
| npr-4 34 |
|
OneToMany | |||
| npr-13 34 |
|
OneToMany | |||
| npr-8 34 |
|
OneToMany |
- Species where no ortholog for GPR19 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for GPR19 Gene
- ENSEMBL:
- Gene Tree for GPR19 (if available)
- TreeFam:
- Gene Tree for GPR19 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GPR19: view image
Paralogs for GPR19 Gene
Variants for GPR19 Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1060500186 | pathogenic, Multiple endocrine neoplasia, type 4 | 12,717,887(-) | GGACG/G | upstream_transcript_variant | |
| rs1060500188 | uncertain-significance, Multiple endocrine neoplasia, type 4 | 12,718,284(-) | GC/TT | upstream_transcript_variant | |
| rs1060500190 | uncertain-significance, Multiple endocrine neoplasia, type 4 | 12,717,919(-) | C/T | upstream_transcript_variant | |
| rs1060500191 | uncertain-significance, Multiple endocrine neoplasia, type 4 | 12,718,136(-) | C/T | upstream_transcript_variant | |
| rs1060500192 | uncertain-significance, Multiple endocrine neoplasia, type 4 | 12,718,200(-) | G/A | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv89n21 | CNV | gain | 19592680 |
| esv2745567 | CNV | deletion | 23290073 |
| nsv1046355 | CNV | loss | 25217958 |
| nsv509456 | CNV | insertion | 20534489 |
| nsv983287 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
37.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.06;
21.74% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GPR19 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- GPR19
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPR19 Gene
Disorders for GPR19 Gene
Additional Disease Information for GPR19
No disorders were found for GPR19 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPR19 Gene
Publications for GPR19 Gene
- A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain. (PMID: 8830667) O'Dowd BF … George SR (FEBS letters 1996) 3 4 58
- G protein-coupled receptor GPR19 regulates E-cadherin expression and invasion of breast cancer cells. (PMID: 28476646) Rao A … Herr DR (Biochimica et biophysica acta 2017) 3 58
- Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. (PMID: 23273568) Yang W … Lau YL (American journal of human genetics 2013) 3 58
- Expression of G protein-coupled receptor 19 in human lung cancer cells is triggered by entry into S-phase and supports G(2)-M cell-cycle progression. (PMID: 22912338) Kastner S … Sommergruber W (Molecular cancer research : MCR 2012) 3 58
- Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L … Andersson-Svahn H (Molecular & cellular proteomics : MCP 2008) 3 58
Products for GPR19 Gene
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- Custom Antibody ServicesOriGene Antibodies for GPR19
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- Taconic Biosciences Mouse Models for GPR19
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- antibodies-online: Search results for 48 available GPR19 Antibodies ranked by validation data
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- antibodies-online: Search results for available GPR19 related products ranked by validation data
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- GeneTex GPR19 Antibody for GPR19
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- Horizon Cell Lines for GPR19
- genomics-online: cdna clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
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- orf clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
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- pCMV6-Entry
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- pPB-N-His
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- pPB-N-His
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- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- genomics-online: gRNA clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
- Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
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- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- genomics-online: primer clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
- Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- genomics-online: shRNA clones - Search results for 155 available GPR19 gene related products
- Overview of 155 available GPR19 gene related products
- Recommended
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pCMV6-Entry
- pCMV6-XL5
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pPB-N-His
- pPB-His-MBP
- pPB-C-His
- pPB-His-GST
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPM-C-His
- pPM-C-HA
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GPR19
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- Boster Bio Antibodies for GPR19
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Sources for GPR19 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
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- (32) SOURCE
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- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
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- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
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