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GPR171 (G Protein-Coupled Receptor 171) is a Protein Coding gene. Diseases associated with GPR171 include Cataract 21, Multiple Types. Among its related pathways are Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and G protein-coupled purinergic nucleotide receptor activity. An important paralog of this gene is P2RY14.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004930 | G protein-coupled receptor activity | NAS | 9370294 |
GO:0045028 | G protein-coupled purinergic nucleotide receptor activity | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | IEA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | NAS | 9370294 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Peptide ligand-binding receptors |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007165 | signal transduction | IEA | -- |
GO:0007186 | G protein-coupled receptor signaling pathway | NAS | 9370294 |
GO:0035589 | G protein-coupled purinergic nucleotide receptor signaling pathway | IEA | -- |
GO:0045638 | negative regulation of myeloid cell differentiation | IEA | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | GPR171 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | GPR171 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | GPR171 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | GPR171 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Gpr171 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Gpr171 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | GPR171 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | GPR171 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | GPR171 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100497564 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | LOC572354 30 |
|
||
GPR171 31 |
|
OneToOne |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2759188 | CNV | gain | 17122850 |
nsv592045 | CNV | gain | 21841781 |
Disorder | Aliases | PubMed IDs |
---|---|---|
cataract 21, multiple types |
|
|