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Aliases for GPR160 Gene

Aliases for GPR160 Gene

  • G Protein-Coupled Receptor 160 2 3 5
  • G-Protein Coupled Receptor GPCR1 3 4
  • GPCR150 3 4
  • HGPCR1 3 4
  • Probable G-Protein Coupled Receptor 160 3
  • Putative G Protein-Coupled Receptor 3
  • GPCR1 3

External Ids for GPR160 Gene

Previous GeneCards Identifiers for GPR160 Gene

  • GC03P171076
  • GC03P171238
  • GC03P169755
  • GC03P167126

Summaries for GPR160 Gene

GeneCards Summary for GPR160 Gene

GPR160 (G Protein-Coupled Receptor 160) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity.

UniProtKB/Swiss-Prot for GPR160 Gene

  • Orphan receptor.

Gene Wiki entry for GPR160 Gene

Additional gene information for GPR160 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPR160 Gene

Genomics for GPR160 Gene

GeneHancer (GH) Regulatory Elements for GPR160 Gene

Promoters and enhancers for GPR160 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J170037 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 689.3 +2.2 2207 4.8 PKNOX1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 IRF4 SLC30A9 ZNF766 ZNF213 GPR160 MYNN GC03P170058
GH03J170059 Promoter 0.5 EPDnew 679 +22.3 22266 0.1 GPR160 RNU7-32P ENSG00000242583 RNU4-38P
GH03J170178 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 30.6 +143.0 143006 3.9 HDGF PKNOX1 CLOCK SMAD1 FOXA2 ARID4B SIN3A FEZF1 DMAP1 ZBTB7B PHC3 GPR160 MYNN SEC62-AS1 RPL22L1 GC03P170161
GH03J170043 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 38 +9.7 9680 7.8 PKNOX1 FOXA2 STAT5A BMI1 FEZF1 BATF ZBTB7B IRF4 ZBTB40 ATF7 GPR160 ENSG00000239219 SEC62 LRRC34 LRRIQ4 SKIL GC03P170058
GH03J170153 Enhancer 1.2 Ensembl ENCODE dbSUPER 35.4 +117.3 117283 2.1 HDGF HDAC1 PKNOX1 TCF12 IKZF2 RUNX3 CREM NCOA1 ELF1 ZEB2 GPR160 GC03P170151 RNU7-32P PHC3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around GPR160 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the GPR160 gene promoter:
  • Sox5
  • AML1a
  • GR-alpha
  • GR
  • Pbx1a
  • NF-E2 p45
  • NF-E2
  • Cdc5
  • PPAR-gamma2
  • PPAR-gamma1

Genomic Locations for GPR160 Gene

Genomic Locations for GPR160 Gene
chr3:170,037,543-170,085,418
(GRCh38/hg38)
Size:
47,876 bases
Orientation:
Plus strand
chr3:169,755,717-169,803,191
(GRCh37/hg19)
Size:
47,475 bases
Orientation:
Plus strand

Genomic View for GPR160 Gene

Genes around GPR160 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPR160 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPR160 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPR160 Gene

Proteins for GPR160 Gene

  • Protein details for GPR160 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UJ42-GP160_HUMAN
    Recommended name:
    Probable G-protein coupled receptor 160
    Protein Accession:
    Q9UJ42
    Secondary Accessions:
    • D3DNQ2

    Protein attributes for GPR160 Gene

    Size:
    338 amino acids
    Molecular mass:
    39787 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GPR160 Gene

Post-translational modifications for GPR160 Gene

  • Glycosylation at Asn8
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for GPR160 Gene

Domains & Families for GPR160 Gene

Gene Families for GPR160 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters

Protein Domains for GPR160 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GPR160 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UJ42

UniProtKB/Swiss-Prot:

GP160_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with GPR160: view

Function for GPR160 Gene

Molecular function for GPR160 Gene

UniProtKB/Swiss-Prot Function:
Orphan receptor.

Phenotypes From GWAS Catalog for GPR160 Gene

Gene Ontology (GO) - Molecular Function for GPR160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with GPR160: view
genes like me logo Genes that share phenotypes with GPR160: view

Animal Model Products

  • Taconic Biosciences Mouse Models for GPR160

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GPR160 Gene

Localization for GPR160 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPR160 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GPR160 gene
Compartment Confidence
plasma membrane 5

Subcellular locations from the

Human Protein Atlas (HPA)
  • Plasma membrane (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for GPR160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA,IDA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0043235 receptor complex IDA 23382219
genes like me logo Genes that share ontologies with GPR160: view

Pathways & Interactions for GPR160 Gene

SuperPathways for GPR160 Gene

No Data Available

Interacting Proteins for GPR160 Gene

Gene Ontology (GO) - Biological Process for GPR160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with GPR160: view

No data available for Pathways by source and SIGNOR curated interactions for GPR160 Gene

Drugs & Compounds for GPR160 Gene

No Compound Related Data Available

Transcripts for GPR160 Gene

mRNA/cDNA for GPR160 Gene

Unigene Clusters for GPR160 Gene

G protein-coupled receptor 160:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPR160 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c
SP1: - - - - - - - -
SP2: - - - - - -
SP3:
SP4: - - - - -
SP5: - - - -
SP6:

Relevant External Links for GPR160 Gene

GeneLoc Exon Structure for
GPR160
ECgene alternative splicing isoforms for
GPR160

Expression for GPR160 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GPR160 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for GPR160 Gene

This gene is overexpressed in Whole Blood (x11.5) and Colon - Transverse (x5.4).

NURSA nuclear receptor signaling pathways regulating expression of GPR160 Gene:

GPR160

SOURCE GeneReport for Unigene cluster for GPR160 Gene:

Hs.231320

Evidence on tissue expression from TISSUES for GPR160 Gene

  • Pancreas(4.2)
  • Stomach(2)
genes like me logo Genes that share expression patterns with GPR160: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GPR160 Gene

Orthologs for GPR160 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GPR160 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPR160 34 33
  • 99.6 (n)
OneToOne
dog
(Canis familiaris)
Mammalia GPR160 34 33
  • 89.25 (n)
OneToOne
cow
(Bos Taurus)
Mammalia GPR160 34 33
  • 86.75 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gpr160 33
  • 74.8 (n)
mouse
(Mus musculus)
Mammalia Gpr160 16 34 33
  • 73.31 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia GPR160 34
  • 55 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GPR160 34
  • 41 (a)
OneToOne
chicken
(Gallus gallus)
Aves GPR160 34 33
  • 60.22 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GPR160 34
  • 44 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gpr160 33
  • 53.99 (n)
MGC76104 33
African clawed frog
(Xenopus laevis)
Amphibia gpcr1-A 33
zebrafish
(Danio rerio)
Actinopterygii gpr160 34 33
  • 45.16 (n)
OneToOne
Species where no ortholog for GPR160 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPR160 Gene

ENSEMBL:
Gene Tree for GPR160 (if available)
TreeFam:
Gene Tree for GPR160 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GPR160: view image

Paralogs for GPR160 Gene

Pseudogenes.org Pseudogenes for GPR160 Gene

genes like me logo Genes that share paralogs with GPR160: view

No data available for Paralogs for GPR160 Gene

Variants for GPR160 Gene

Sequence variations from dbSNP and Humsavar for GPR160 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000030836 -- 170,041,073(+) G/C genic_upstream_transcript_variant, intron_variant
rs1000057285 -- 170,038,669(+) T/C genic_upstream_transcript_variant, intron_variant
rs1000077320 -- 170,038,006(+) T/C 5_prime_UTR_variant, coding_sequence_variant, genic_upstream_transcript_variant, non_coding_transcript_variant, synonymous_variant, upstream_transcript_variant
rs1000118382 -- 170,045,479(+) T/C genic_upstream_transcript_variant, intron_variant
rs1000195728 -- 170,037,765(+) C/T 5_prime_UTR_variant, genic_upstream_transcript_variant, non_coding_transcript_variant, upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for GPR160 Gene

Variant ID Type Subtype PubMed ID
nsv7356 OTHER inversion 18451855
nsv1009884 CNV gain 25217958
esv2726189 CNV deletion 23290073
dgv8728n54 CNV loss 21841781

Variation tolerance for GPR160 Gene

Residual Variation Intolerance Score: 85.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.96; 36.33% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GPR160 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GPR160

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPR160 Gene

Disorders for GPR160 Gene

Additional Disease Information for GPR160

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for GPR160 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPR160 Gene

Publications for GPR160 Gene

  1. Identification of G protein-coupled receptor genes from the human genome sequence. (PMID: 12044878) Takeda S … Mitaku S (FEBS letters 2002) 2 3 4 58
  2. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M … Yamada Y (American journal of hypertension 2010) 3 44 58
  3. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PMID: 20198315) Yoshida T … Yamada Y (International journal of molecular medicine 2010) 3 44 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. Mining of assembled expressed sequence tag (EST) data for protein families: application to the G protein-coupled receptor superfamily. (PMID: 11466977) Conklin D … Vissing H (Briefings in bioinformatics 2000) 3 4 58

Products for GPR160 Gene

Sources for GPR160 Gene

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