Aliases for GPR151 Gene
External Ids for GPR151 Gene
Previous GeneCards Identifiers for GPR151 Gene
This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the SOG subfamily that includes somatostatin, opioid, galanin, and kisspeptin receptors. The orthologous mouse gene has a restricted pattern of neuronal expression which is induced following nerve injury. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]
GeneCards Summary for GPR151 Gene
GPR151 (G Protein-Coupled Receptor 151) is a Protein Coding gene. Diseases associated with GPR151 include Brachial Plexus Lesion. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is RXFP3.
UniProtKB/Swiss-Prot Summary for GPR151 Gene
Proton-sensing G-protein coupled receptor.