Aliases for GPR150 Gene
External Ids for GPR150 Gene
Previous GeneCards Identifiers for GPR150 Gene
This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]
GeneCards Summary for GPR150 Gene
GPR150 (G Protein-Coupled Receptor 150) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and G alpha (s) signalling events. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is AVPR1B.
UniProtKB/Swiss-Prot Summary for GPR150 Gene