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GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]
GPR142 (G Protein-Coupled Receptor 142) is a Protein Coding gene. Diseases associated with GPR142 include Fusariosis. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is GPR139.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004930 | G protein-coupled receptor activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005829 | cytosol | IDA | -- |
GO:0005886 | plasma membrane | IEA,IDA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO:0030054 | cell junction | IDA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007165 | signal transduction | IEA | -- |
GO:0007186 | G protein-coupled receptor signaling pathway | IEA | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | GPR142 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | GPR142 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | GPR142 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Gpr142 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Gpr142 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | GPR142 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | GPR142 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | GPR142 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | gpr142 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | LOC100000501 30 |
|
||
gpr142 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
716231 | Benign: not provided | 74,371,859(+) | C/T | SYNONYMOUS_VARIANT | |
716465 | Likely Benign: not provided | 74,372,328(+) | C/T | MISSENSE_VARIANT | |
770799 | Likely Benign: not provided | 74,370,524(+) | GC/G | FRAMESHIFT_VARIANT | |
774932 | Benign: not provided | 74,372,244(+) | C/A | SYNONYMOUS_VARIANT | |
777216 | Benign: not provided | 74,370,533(+) | G/A | MISSENSE_VARIANT |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv12e196 | CNV | duplication | 17116639 |
dgv3282n100 | CNV | gain | 25217958 |
dgv372n27 | CNV | gain | 19166990 |
dgv5768n54 | CNV | gain | 21841781 |
esv2751770 | CNV | gain | 17911159 |
esv2761978 | CNV | gain | 21179565 |
esv33995 | CNV | loss | 17666407 |
esv3573820 | CNV | gain | 25503493 |
esv3641230 | CNV | gain | 21293372 |
esv3641237 | CNV | gain | 21293372 |
nsv509673 | CNV | insertion | 20534489 |
nsv517569 | CNV | gain+loss | 19592680 |
nsv833538 | CNV | gain | 17160897 |
nsv833539 | CNV | loss | 17160897 |
Disorder | Aliases | PubMed IDs |
---|---|---|
fusariosis |
|
|