Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the co... See more...

Aliases for GPC5 Gene

Aliases for GPC5 Gene

  • Glypican 5 2 3 5
  • Glypican Proteoglycan 5 2 3
  • Glypican-5 3 4
  • BA93M14.1 3

External Ids for GPC5 Gene

Previous GeneCards Identifiers for GPC5 Gene

  • GC13P090410
  • GC13P086438
  • GC13P090887
  • GC13P089749
  • GC13P089748
  • GC13P090848
  • GC13P092050
  • GC13P072646

Summaries for GPC5 Gene

Entrez Gene Summary for GPC5 Gene

  • Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008]

GeneCards Summary for GPC5 Gene

GPC5 (Glypican 5) is a Protein Coding gene. Diseases associated with GPC5 include Omodysplasia and Tumoral Calcinosis, Hyperphosphatemic, Familial, 1. Among its related pathways are Microglia Activation During Neuroinflammation: Overview and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include heparan sulfate proteoglycan binding. An important paralog of this gene is GPC3.

UniProtKB/Swiss-Prot Summary for GPC5 Gene

Gene Wiki entry for GPC5 Gene

Additional gene information for GPC5 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GPC5 Gene

Genomics for GPC5 Gene

GeneHancer (GH) Regulatory Elements for GPC5 Gene

Promoters and enhancers for GPC5 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J091398 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE CraniofacialAtlas 506.5 +0.2 155 1.3 ZIC2 REST ZBTB26 ZNF341 EZH2 POLR2A KLF9 TBL1XR1 MAX PHF8 GPC5 piR-35674-129
GH13J091399 Promoter 0.6 Ensembl 500.7 +1.1 1082 0.2 EZH2 RELA SUZ12 EBF1 GPC5 piR-35674-129
GH13J091346 Promoter/Enhancer 1.8 Ensembl ENCODE CraniofacialAtlas dbSUPER 4.6 -49.6 -49618 5.2 RXRA FOXK2 EP300 CTCF ZSCAN5C SIN3A TCF12 MYC POLR2G NCOR1 AJ421736 MIR17 MIR17HG MIR18A MIR19A piR-37523 GPC5 4F3T_R AB372624 MIR19B1
GH13J091329 Enhancer 0.7 Ensembl 10 -68.7 -68718 0.6 ZNF623 ZNF510 ZNF426 ZNF213 ZNF189 ZNF529 ZNF34 ZFP37 ZNF433 REST GPC5 MIR17HG PPIAP23
GH13J092103 Enhancer 0.7 Ensembl ENCODE 4.6 +705.4 705382 0.8 FOXA1 NR2F2 ESR1 RXRA TCF7L2 TRIM28 PKNOX1 GPC5 piR-52225-001 piR-38051-088
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GPC5 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GPC5

Top Transcription factor binding sites by QIAGEN in the GPC5 gene promoter:
  • AML1a
  • AP-2gamma
  • E47
  • FOXD3
  • Nkx6-1
  • Sox9
  • SRF
  • SRF (504 AA)
  • Tal-1
  • XBP-1

Genomic Locations for GPC5 Gene

Genomic Locations for GPC5 Gene
chr13:91,398,619-92,873,682
(GRCh38/hg38)
Size:
1,475,064 bases
Orientation:
Plus strand
chr13:92,050,929-93,519,490
(GRCh37/hg19)
Size:
1,468,562 bases
Orientation:
Plus strand

Genomic View for GPC5 Gene

Genes around GPC5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPC5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPC5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPC5 Gene

Proteins for GPC5 Gene

  • Protein details for GPC5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P78333-GPC5_HUMAN
    Recommended name:
    Glypican-5
    Protein Accession:
    P78333
    Secondary Accessions:
    • B2R726
    • O60436
    • Q9BX27

    Protein attributes for GPC5 Gene

    Size:
    572 amino acids
    Molecular mass:
    63707 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GPC5 Gene

Post-translational modifications for GPC5 Gene

  • Glycosylation at Asn120, Asn237, Ser441, Ser486, Ser495, Ser507, Ser509, and Asn527
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for GPC5 Gene

Domains & Families for GPC5 Gene

Gene Families for GPC5 Gene

Protein Domains for GPC5 Gene

Blocks:
  • Glypican
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GPC5 Gene

GenScript: Design optimal peptide antigens:
  • Glypican-5 (GPC5_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P78333

UniProtKB/Swiss-Prot:

GPC5_HUMAN :
  • Belongs to the glypican family.
Family:
  • Belongs to the glypican family.
genes like me logo Genes that share domains with GPC5: view

Function for GPC5 Gene

Molecular function for GPC5 Gene

UniProtKB/Swiss-Prot Function:
Cell surface proteoglycan that bears heparan sulfate.
GENATLAS Biochemistry:
glypican 5,60kDa,extracellular proteoglycan,highly homolog with rat glypican OCI-5 expressed in fetal brain,lung and liver and adult brain,involved in the control of cellular response to growth factors and adhesion factors

Phenotypes From GWAS Catalog for GPC5 Gene

genes like me logo Genes that share phenotypes with GPC5: view

Animal Models for GPC5 Gene

MGI Knock Outs for GPC5:
  • Gpc5 Gpc5<tm1a(KOMP)Wtsi>

Clone Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GPC5 Gene

Localization for GPC5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPC5 Gene

Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
[Secreted glypican-5]: Secreted, extracellular space.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GPC5 gene
Compartment Confidence
plasma membrane 4
extracellular 4
lysosome 4
golgi apparatus 4
nucleus 3
cytoskeleton 2
cytosol 2
mitochondrion 1
endoplasmic reticulum 1
endosome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for GPC5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS,IBA --
GO:0005615 extracellular space IEA --
GO:0005796 Golgi lumen TAS --
GO:0005886 plasma membrane TAS,IEA --
GO:0009986 cell surface IBA 21873635
genes like me logo Genes that share ontologies with GPC5: view

Pathways & Interactions for GPC5 Gene

genes like me logo Genes that share pathways with GPC5: view

Interacting Proteins for GPC5 Gene

;

Gene Ontology (GO) - Biological Process for GPC5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001523 retinoid metabolic process TAS --
GO:0006024 glycosaminoglycan biosynthetic process TAS --
GO:0006027 glycosaminoglycan catabolic process TAS --
GO:0009966 regulation of signal transduction IEA --
GO:0016477 cell migration IBA 21873635
genes like me logo Genes that share ontologies with GPC5: view

No data available for SIGNOR curated interactions for GPC5 Gene

Drugs & Compounds for GPC5 Gene

No Compound Related Data Available

Transcripts for GPC5 Gene

mRNA/cDNA for GPC5 Gene

1 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPC5 Gene

No ASD Table

Relevant External Links for GPC5 Gene

GeneLoc Exon Structure for
GPC5

Expression for GPC5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GPC5 Gene

mRNA differential expression in normal tissues according to GTEx for GPC5 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x7.7), Brain - Caudate (basal ganglia) (x7.0), Brain - Putamen (basal ganglia) (x6.2), and Brain - Amygdala (x5.4).

Protein differential expression in normal tissues from HIPED for GPC5 Gene

This gene is overexpressed in Pancreatic juice (57.7) and Frontal cortex (9.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GPC5 Gene



Protein tissue co-expression partners for GPC5 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GPC5

SOURCE GeneReport for Unigene cluster for GPC5 Gene:

Hs.655675

mRNA Expression by UniProt/SwissProt for GPC5 Gene:

P78333-GPC5_HUMAN
Tissue specificity: In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver.

Evidence on tissue expression from TISSUES for GPC5 Gene

  • Nervous system(4.5)
genes like me logo Genes that share expression patterns with GPC5: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for GPC5 Gene

Orthologs for GPC5 Gene

This gene was present in the common ancestor of animals.

Orthologs for GPC5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPC5 31 30
  • 99.07 (n)
OneToOne
cow
(Bos Taurus)
Mammalia GPC5 31 30
  • 88.09 (n)
OneToOne
dog
(Canis familiaris)
Mammalia GPC5 31 30
  • 87.27 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Gpc5 17 31 30
  • 84.85 (n)
rat
(Rattus norvegicus)
Mammalia Gpc5 30
  • 83.86 (n)
oppossum
(Monodelphis domestica)
Mammalia GPC5 31
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GPC5 31
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves GPC5 31 30
  • 74.74 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 31
  • 40 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii LOC559454 30
  • 58.5 (n)
GPC5 31
  • 55 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta dally 31 32 30
  • 42.84 (n)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005799 30
  • 40.86 (n)
Species where no ortholog for GPC5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPC5 Gene

ENSEMBL:
Gene Tree for GPC5 (if available)
TreeFam:
Gene Tree for GPC5 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GPC5: view image

Paralogs for GPC5 Gene

Paralogs for GPC5 Gene

(2) SIMAP similar genes for GPC5 Gene using alignment to 1 proteins:

  • GPC5_HUMAN
genes like me logo Genes that share paralogs with GPC5: view

Variants for GPC5 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GPC5 Gene

SNP ID Clinical significance and condition Chr 13 pos Variation AA Info Type
714328 Benign: not provided 91,693,344(+) A/G SYNONYMOUS_VARIANT
722397 Benign: not provided 91,399,199(+) G/A SYNONYMOUS_VARIANT
788447 Benign: not provided 91,693,852(+) C/T MISSENSE_VARIANT
rs553717 - p.Ala155Val

Additional dbSNP identifiers (rs#s) for GPC5 Gene

Structural Variations from Database of Genomic Variants (DGV) for GPC5 Gene

Variant ID Type Subtype PubMed ID
dgv1013n106 CNV tandem duplication 24896259
dgv120e215 CNV deletion 23714750
dgv1729n100 CNV loss 25217958
dgv1730n100 CNV gain 25217958
dgv3318n54 CNV loss 21841781
dgv3319n54 CNV loss 21841781
dgv3320n54 CNV loss 21841781
dgv3321n54 CNV loss 21841781
dgv3322n54 CNV loss 21841781
dgv3323n54 CNV loss 21841781
dgv370e199 CNV deletion 23128226
dgv371e199 CNV deletion 23128226
dgv567e212 CNV loss 25503493
dgv568e212 CNV loss 25503493
dgv569e212 CNV loss 25503493
dgv570e212 CNV loss 25503493
esv1107756 CNV insertion 17803354
esv1320980 CNV deletion 17803354
esv1383574 CNV insertion 17803354
esv1512558 CNV insertion 17803354
esv1606660 CNV insertion 17803354
esv21499 CNV loss 19812545
esv2258713 CNV deletion 18987734
esv24496 CNV gain 19812545
esv2547862 CNV insertion 19546169
esv2650286 CNV deletion 19546169
esv2656933 CNV deletion 23128226
esv2658739 CNV deletion 23128226
esv2659093 CNV deletion 23128226
esv2662445 CNV deletion 23128226
esv2662502 CNV deletion 23128226
esv2664583 CNV deletion 23128226
esv2665629 CNV deletion 23128226
esv2668276 CNV deletion 23128226
esv2669187 CNV deletion 23128226
esv2671333 CNV deletion 23128226
esv2672157 CNV deletion 23128226
esv2672717 CNV deletion 23128226
esv2674448 CNV deletion 23128226
esv2677684 CNV deletion 23128226
esv2678676 CNV deletion 23128226
esv2678981 CNV deletion 23128226
esv2747809 CNV deletion 23290073
esv2747810 CNV deletion 23290073
esv2747811 CNV deletion 23290073
esv2747812 CNV deletion 23290073
esv2747813 CNV deletion 23290073
esv2747814 CNV deletion 23290073
esv2747815 CNV deletion 23290073
esv2760298 CNV loss 21179565
esv28000 CNV loss 19812545
esv28030 CNV gain 19812545
esv3303582 CNV mobile element insertion 20981092
esv3304975 CNV mobile element insertion 20981092
esv3307073 CNV mobile element insertion 20981092
esv3308432 CNV mobile element insertion 20981092
esv3308491 CNV mobile element insertion 20981092
esv3309855 CNV mobile element insertion 20981092
esv3324602 CNV insertion 20981092
esv3358081 CNV insertion 20981092
esv3373534 CNV insertion 20981092
esv3379657 CNV insertion 20981092
esv3398241 CNV insertion 20981092
esv3432629 CNV insertion 20981092
esv3550877 CNV deletion 23714750
esv3550884 CNV deletion 23714750
esv3550890 CNV deletion 23714750
esv3550891 CNV deletion 23714750
esv3550892 CNV deletion 23714750
esv3550893 CNV deletion 23714750
esv3550895 CNV deletion 23714750
esv3580809 CNV loss 25503493
esv3580810 CNV loss 25503493
esv3580811 CNV loss 25503493
esv3580813 CNV loss 25503493
esv3580815 CNV loss 25503493
esv3580817 CNV loss 25503493
esv3580818 CNV loss 25503493
esv3580823 CNV loss 25503493
esv3582682 CNV gain 25503493
esv3582694 CNV gain 25503493
esv3582705 CNV gain 25503493
esv3584661 CNV loss 24956385
esv3633152 CNV loss 21293372
esv3633154 CNV loss 21293372
esv3633155 CNV loss 21293372
esv3633156 CNV loss 21293372
esv3633159 CNV loss 21293372
esv3633160 CNV loss 21293372
esv3633162 CNV loss 21293372
esv3633163 CNV loss 21293372
esv3633164 CNV loss 21293372
esv3633166 CNV gain 21293372
esv3633167 CNV loss 21293372
esv3633170 CNV loss 21293372
esv3633173 CNV loss 21293372
esv3633174 CNV loss 21293372
esv3633175 CNV loss 21293372
esv3633176 CNV loss 21293372
esv3633177 CNV loss 21293372
esv3633179 CNV loss 21293372
esv3633181 CNV loss 21293372
esv3633182 CNV gain 21293372
esv3633183 CNV loss 21293372
esv3892423 CNV loss 25118596
esv3892425 CNV gain 25118596
nsv1035365 CNV loss 25217958
nsv1040709 CNV loss 25217958
nsv1041168 CNV loss 25217958
nsv1041361 CNV loss 25217958
nsv1042985 CNV loss 25217958
nsv1045395 CNV gain 25217958
nsv1049238 CNV loss 25217958
nsv1070188 CNV deletion 25765185
nsv1071116 CNV deletion 25765185
nsv1113593 CNV deletion 24896259
nsv1116508 OTHER inversion 24896259
nsv1120 CNV deletion 18451855
nsv1120098 OTHER inversion 24896259
nsv1120287 CNV tandem duplication 24896259
nsv1120418 CNV deletion 24896259
nsv1120419 CNV deletion 24896259
nsv1120420 CNV deletion 24896259
nsv1122 CNV insertion 18451855
nsv1122852 CNV deletion 24896259
nsv1123 CNV insertion 18451855
nsv1124 CNV deletion 18451855
nsv1125 CNV insertion 18451855
nsv1127349 CNV deletion 24896259
nsv1127350 CNV deletion 24896259
nsv1127351 CNV deletion 24896259
nsv1133197 CNV tandem duplication 24896259
nsv1138250 CNV deletion 24896259
nsv1148715 CNV deletion 26484159
nsv456066 CNV gain 19166990
nsv456068 CNV gain 19166990
nsv456069 CNV loss 19166990
nsv456072 CNV loss 19166990
nsv471168 CNV loss 18288195
nsv473160 CNV novel sequence insertion 20440878
nsv474769 CNV novel sequence insertion 20440878
nsv498819 CNV loss 21111241
nsv514714 CNV gain+loss 21397061
nsv514715 CNV loss 21397061
nsv518324 CNV loss 19592680
nsv521051 CNV loss 19592680
nsv524271 CNV loss 19592680
nsv526003 CNV loss 19592680
nsv527287 CNV loss 19592680
nsv527713 CNV loss 19592680
nsv528318 CNV loss 19592680
nsv562718 CNV loss 21841781
nsv562719 CNV loss 21841781
nsv562720 CNV loss 21841781
nsv562721 CNV loss 21841781
nsv562722 CNV gain 21841781
nsv562723 CNV gain 21841781
nsv562724 CNV loss 21841781
nsv562725 CNV gain 21841781
nsv562726 CNV loss 21841781
nsv562727 CNV gain 21841781
nsv562728 CNV loss 21841781
nsv562729 CNV loss 21841781
nsv562730 CNV loss 21841781
nsv562745 CNV gain 21841781
nsv562746 CNV loss 21841781
nsv818987 CNV loss 17921354
nsv826749 CNV loss 20364138
nsv832680 CNV gain 17160897
nsv951906 CNV deletion 24416366
nsv951907 CNV duplication 24416366
nsv957468 CNV insertion 24416366
nsv958095 CNV deletion 24416366
nsv958151 CNV deletion 24416366
nsv974112 CNV duplication 23825009
nsv974113 CNV duplication 23825009
nsv974114 CNV duplication 23825009
nsv974115 CNV duplication 23825009
nsv974116 CNV duplication 23825009
nsv974117 CNV duplication 23825009
nsv976145 CNV duplication 23825009
nsv977266 CNV duplication 23825009
nsv977267 CNV duplication 23825009
nsv977269 CNV duplication 23825009
nsv983613 CNV duplication 23825009

Variation tolerance for GPC5 Gene

Residual Variation Intolerance Score: 50.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.82; 86.87% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GPC5 Gene

Human Gene Mutation Database (HGMD)
GPC5
SNPedia medical, phenotypic, and genealogical associations of SNPs for
GPC5

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPC5 Gene

Disorders for GPC5 Gene

MalaCards: The human disease database

(3) MalaCards diseases for GPC5 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
omodysplasia
  • omodysplasia 2
tumoral calcinosis, hyperphosphatemic, familial, 1
  • hftc1
tetralogy of fallot
  • tof
- elite association - COSMIC cancer census association via MalaCards
Search GPC5 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for GPC5

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with GPC5: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GPC5 Gene

Publications for GPC5 Gene

  1. Genetic variants and risk of lung cancer in never smokers: a genome-wide association study. (PMID: 20304703) Li Y … Yang P (The Lancet. Oncology 2010) 2 3 41 54
  2. Glypican 5 is an interferon-beta response gene: a replication study. (PMID: 19556317) Cénit MD … Martínez A (Multiple sclerosis (Houndmills, Basingstoke, England) 2009) 2 3 41 54
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A … Ross MT (Nature 2004) 2 3 4 54
  4. Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family. (PMID: 9070915) Veugelers M … David G (Genomics 1997) 2 3 4 54
  5. Common variation in GPC5 is associated with acquired nephrotic syndrome. (PMID: 21441931) Okamoto K … Noiri E (Nature genetics 2011) 3 41 54

Products for GPC5 Gene

  • Boster Bio Antibodies for GPC5
  • Boster Bio ELISA Kits for GPC5

Sources for GPC5 Gene