External Ids for GPC5 Gene
Previous GeneCards Identifiers for GPC5 Gene
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008]
GeneCards Summary for GPC5 Gene
GPC5 (Glypican 5) is a Protein Coding gene. Diseases associated with GPC5 include Simpson-Golabi-Behmel Syndrome and Tetralogy Of Fallot. Among its related pathways are Chondroitin sulfate/dermatan sulfate metabolism and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include heparan sulfate proteoglycan binding. An important paralog of this gene is GPC3.
UniProtKB/Swiss-Prot for GPC5 Gene
Cell surface proteoglycan that bears heparan sulfate.