Aliases for GPA33 Gene
External Ids for GPA33 Gene
Previous GeneCards Identifiers for GPA33 Gene
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]
GeneCards Summary for GPA33 Gene
UniProtKB/Swiss-Prot Summary for GPA33 Gene
May play a role in cell-cell recognition and signaling.