Aliases for GPA33 Gene
External Ids for GPA33 Gene
Previous GeneCards Identifiers for GPA33 Gene
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]
GeneCards Summary for GPA33 Gene
GPA33 (Glycoprotein A33) is a Protein Coding gene. Diseases associated with GPA33 include Infant Botulism and Colorectal Cancer. Gene Ontology (GO) annotations related to this gene include receptor activity. An important paralog of this gene is IGSF11.
UniProtKB/Swiss-Prot for GPA33 Gene
May play a role in cell-cell recognition and signaling.