Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes t... See more...

Aliases for GP1BB Gene

Aliases for GP1BB Gene

  • Glycoprotein Ib Platelet Subunit Beta 2 3 5
  • Platelet Glycoprotein Ib Beta Chain 2 3 4
  • Glycoprotein Ib (Platelet), Beta Polypeptide 2 3
  • Antigen CD42b-Beta 3 4
  • GP-Ib Beta 3 4
  • Nuclear Localization Signal Deleted In Velocardiofacial Syndrome 3
  • Truncated Platelet Membrane Glycoprotein Ib Beta 3
  • Platelet Membrane Glycoprotein Ib Beta 3
  • Glycoprotein Ib Platelet Beta Subunit 3
  • CD42c Antigen 4
  • GPIb-Beta 4
  • GPIbbeta 3
  • BDPLT1 3
  • CD42C 3
  • GPIBB 3
  • GPIbB 4
  • BS 3

External Ids for GP1BB Gene

Previous GeneCards Identifiers for GP1BB Gene

  • GC22P016643
  • GC22P018085
  • GC22P019710
  • GC22P003331

Summaries for GP1BB Gene

Entrez Gene Summary for GP1BB Gene

  • Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described; however, the authenticity of this product has been questioned. Yet another less abundant GPIb beta mRNA species of 3.5 kb, expressed in nonhematopoietic tissues such as endothelium, brain and heart, was shown to result from inefficient usage of a non-consensus polyA signal in the neighboring upstream gene (SEPT5, septin 5). In the absence of polyadenylation from its own imperfect site, the SEPT5 gene produces read-through transcripts that use the consensus polyA signal of this gene. [provided by RefSeq, Dec 2010]

GeneCards Summary for GP1BB Gene

GP1BB (Glycoprotein Ib Platelet Subunit Beta) is a Protein Coding gene. Diseases associated with GP1BB include Bernard-Soulier Syndrome and Autosomal Dominant Macrothrombocytopenia. Among its related pathways are Hematopoietic cell lineage and Formation of Fibrin Clot (Clotting Cascade). Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity. An important paralog of this gene is GP9.

UniProtKB/Swiss-Prot Summary for GP1BB Gene

  • Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium.

Gene Wiki entry for GP1BB Gene

Additional gene information for GP1BB Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GP1BB Gene

Genomics for GP1BB Gene

GeneHancer (GH) Regulatory Elements for GP1BB Gene

Promoters and enhancers for GP1BB Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J019722 Promoter/Enhancer 1.8 VISTA EPDnew Ensembl ENCODE 500.7 +0.5 478 2 CTCF PHB2 ZNF263 TAF7 AFF1 TRIM28 TARDBP REST DNMT1 HES1 GP1BB E2F6P1 TRMT2A LINC01311 DGCR8 TBX1 ENSG00000215493 UFD1 RANBP1 ZDHHC8
GH22J019721 Promoter 0.9 EPDnew 500.7 -1.0 -1005 0.1 RUNX1 RELA CREB3L1 MAX POLR2G E2F6 NCOA1 SETDB1 MCM7 SIN3A GP1BB SEPT5-GP1BB SEPTIN5
GH22J019724 Enhancer 0.8 ENCODE 500.7 -0.6 -554 0 HES1 CTBP1 MYC NCOR1 ZNF282 MAX POLR2G KLF13 ZFHX2 BCOR GP1BB SEPT5-GP1BB SEPTIN5
GH22J019662 Enhancer 1.1 Ensembl ENCODE CraniofacialAtlas 12.8 -57.7 -57744 5.2 ZNF10 ZBTB5 ZIC2 ZNF423 TSC22D4 RUNX1 MYC HINFP MCM3 MXI1 ENSG00000225007 ENSG00000235776 DGCR11 SEPTIN5 GP1BB MED15 SCARF2 UFD1 LOC100420103
GH22J019691 Enhancer 1.1 ENCODE CraniofacialAtlas 13.3 -31.0 -31022 1.3 ZNF217 TEAD4 AFF1 TRIM28 TARDBP KLF4 HES1 TSC22D4 NR3C1 TOE1 SEPTIN5 GP1BB ABHD17AP4 HSALNG0134036 piR-60051-067
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GP1BB on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GP1BB

Top Transcription factor binding sites by QIAGEN in the GP1BB gene promoter:
  • AP-1
  • c-Fos
  • c-Jun
  • CREB
  • deltaCREB
  • FosB
  • Fra-1
  • GATA-2
  • JunB
  • JunD

Genomic Locations for GP1BB Gene

Genomic Locations for GP1BB Gene
chr22:19,722,945-19,724,774
(GRCh38/hg38)
Size:
1,830 bases
Orientation:
Plus strand
chr22:19,710,468-19,712,297
(GRCh37/hg19)
Size:
1,830 bases
Orientation:
Plus strand

Genomic View for GP1BB Gene

Genes around GP1BB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GP1BB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GP1BB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GP1BB Gene

Proteins for GP1BB Gene

  • Protein details for GP1BB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P13224-GP1BB_HUMAN
    Recommended name:
    Platelet glycoprotein Ib beta chain
    Protein Accession:
    P13224
    Secondary Accessions:
    • Q14422
    • Q8NG40

    Protein attributes for GP1BB Gene

    Size:
    206 amino acids
    Molecular mass:
    21718 Da
    Quaternary structure:
    • Two GP-Ib beta are disulfide-linked to one GP-Ib alpha. GP-IX is complexed with the GP-Ib heterodimer via a non covalent linkage.
    Miscellaneous:
    • Platelet activation apparently involves disruption of the macromolecular complex of GP-Ib with the platelet glycoprotein IX (GP-IX) and dissociation of GP-Ib from the actin-binding protein.

    Three dimensional structures from OCA and Proteopedia for GP1BB Gene

    Alternative splice isoforms for GP1BB Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GP1BB Gene

Post-translational modifications for GP1BB Gene

  • Glycosylation at Asn66 and Thr83
  • Modification sites at PhosphoSitePlus

Other Protein References for GP1BB Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Abcam antibodies for GP1BB
  • Santa Cruz Biotechnology (SCBT) Antibodies for GP1BB

No data available for DME Specific Peptides for GP1BB Gene

Domains & Families for GP1BB Gene

Gene Families for GP1BB Gene

HGNC:
Human Protein Atlas (HPA):
  • CD markers
  • Disease related genes
  • Predicted membrane proteins

Protein Domains for GP1BB Gene

Blocks:
  • Cysteine-rich flanking region, C-terminal
  • Leucine-rich repeat signature
  • Cysteine-rich flanking region, N-terminal
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GP1BB Gene

GenScript: Design optimal peptide antigens:
  • Platelet glycoprotein Ib beta chain (F1C636_HUMAN)
  • Antigen CD42b-beta (GP1BB_HUMAN)
genes like me logo Genes that share domains with GP1BB: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for GP1BB Gene

Function for GP1BB Gene

Molecular function for GP1BB Gene

UniProtKB/Swiss-Prot Function:
Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium.
GENATLAS Biochemistry:
platelet glycoprotein Ib,beta (22kDa),overlapping the 3'utr of PNUTL1 in the same orientation,linked to GP1BA through disulfide bonds in von Willebrand receptor

Phenotypes From GWAS Catalog for GP1BB Gene

Gene Ontology (GO) - Molecular Function for GP1BB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity NAS 3353370
GO:0005515 protein binding IPI 4044584
GO:0042802 identical protein binding IPI 18674540
genes like me logo Genes that share ontologies with GP1BB: view
genes like me logo Genes that share phenotypes with GP1BB: view

Human Phenotype Ontology for GP1BB Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for GP1BB Gene

MGI Knock Outs for GP1BB:

Animal Model Products

CRISPR Products

miRNA for GP1BB Gene

miRTarBase miRNAs that target GP1BB

Clone Products

  • Addgene plasmids for GP1BB

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for GP1BB Gene

Localization for GP1BB Gene

Subcellular locations from UniProtKB/Swiss-Prot for GP1BB Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GP1BB gene
Compartment Confidence
plasma membrane 5
extracellular 3
cytoskeleton 1
nucleus 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1
lysosome 0

Gene Ontology (GO) - Cellular Components for GP1BB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane NAS 3353370
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with GP1BB: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for GP1BB Gene

Pathways & Interactions for GP1BB Gene

genes like me logo Genes that share pathways with GP1BB: view

SIGNOR curated interactions for GP1BB Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for GP1BB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007155 cell adhesion IEA --
GO:0007166 cell surface receptor signaling pathway NAS 3353370
GO:0007596 blood coagulation TAS --
GO:0007597 blood coagulation, intrinsic pathway TAS --
GO:0007599 hemostasis IEA --
genes like me logo Genes that share ontologies with GP1BB: view

Drugs & Compounds for GP1BB Gene

(1) Drugs for GP1BB Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(2) Additional Compounds for GP1BB Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with GP1BB: view

Transcripts for GP1BB Gene

mRNA/cDNA for GP1BB Gene

1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

  • Addgene plasmids for GP1BB

Alternative Splicing Database (ASD) splice patterns (SP) for GP1BB Gene

No ASD Table

Relevant External Links for GP1BB Gene

GeneLoc Exon Structure for
GP1BB

Expression for GP1BB Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GP1BB Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for GP1BB Gene

This gene is overexpressed in Platelet (41.0), Peripheral blood mononuclear cells (15.4), and Neutrophil (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GP1BB Gene



Protein tissue co-expression partners for GP1BB Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GP1BB

SOURCE GeneReport for Unigene cluster for GP1BB Gene:

Hs.283743

mRNA Expression by UniProt/SwissProt for GP1BB Gene:

P13224-GP1BB_HUMAN
Tissue specificity: Expressed in heart and brain.

Evidence on tissue expression from TISSUES for GP1BB Gene

  • Blood(4.5)
  • Liver(4.1)
  • Nervous system(4.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for GP1BB Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • immune
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • cheek
  • chin
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • head
  • hypothalamus
  • jaw
  • larynx
  • lip
  • mandible
  • maxilla
  • middle ear
  • mouth
  • neck
  • nose
  • outer ear
  • parathyroid
  • pharynx
  • pituitary gland
  • skull
  • thyroid
  • tongue
  • tooth
  • vocal cord
Thorax:
  • aorta
  • chest wall
  • clavicle
  • heart
  • heart valve
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
  • thymus
Abdomen:
  • abdominal wall
  • biliary tract
  • gallbladder
  • intestine
  • kidney
  • large intestine
  • liver
  • pancreas
  • small intestine
  • spleen
Pelvis:
  • pelvis
  • rectum
  • ureter
  • uterus
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • bone marrow
  • coagulation system
  • hair
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • spinal column
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with GP1BB: view

No data available for mRNA differential expression in normal tissues for GP1BB Gene

Orthologs for GP1BB Gene

This gene was present in the common ancestor of chordates.

Orthologs for GP1BB Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GP1BB 31
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gp1bb 17 31 30
  • 87.61 (n)
dog
(Canis familiaris)
Mammalia GP1BB 31 30
  • 87.16 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gp1bb 30
  • 84.68 (n)
cow
(Bos Taurus)
Mammalia GP1BB 31
  • 84 (a)
OneToOne
chicken
(Gallus gallus)
Aves GP1BB 31
  • 35 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GP1BB 31
  • 38 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gp1bb 30
  • 48.89 (n)
zebrafish
(Danio rerio)
Actinopterygii gp1bb 31 30
  • 58.4 (n)
OneToOne
Species where no ortholog for GP1BB was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GP1BB Gene

ENSEMBL:
Gene Tree for GP1BB (if available)
TreeFam:
Gene Tree for GP1BB (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GP1BB: view image

Paralogs for GP1BB Gene

Paralogs for GP1BB Gene

(1) SIMAP similar genes for GP1BB Gene using alignment to 2 proteins:

  • GP1BB_HUMAN
  • F1C636_HUMAN
genes like me logo Genes that share paralogs with GP1BB: view

Variants for GP1BB Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GP1BB Gene

SNP ID Clinical significance and condition Chr 22 pos Variation AA Info Type
626963 Uncertain Significance: Abnormal bleeding 19,723,949(+) C/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
627039 Likely Pathogenic: Thrombocytopenia 19,724,070(+) ACGCGCTGCC/A NON_CODING_TRANSCRIPT_VARIANT,INFRAME_DELETION
627056 Likely Pathogenic: Thrombocytopenia 19,724,238(+) T/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
627061 Uncertain Significance: Thrombocytopenia 19,724,250(+) A/G MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
627068 Uncertain Significance: Thrombocytopenia 19,724,277(+) C/G MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for GP1BB Gene

Structural Variations from Database of Genomic Variants (DGV) for GP1BB Gene

Variant ID Type Subtype PubMed ID
dgv725n67 CNV gain 20364138
esv22571 CNV loss 19812545
esv2751940 CNV gain 17911159
esv3575418 CNV gain 25503493
esv3647279 CNV gain 21293372
esv3893434 CNV gain 25118596
nsv517478 CNV loss 19592680
nsv588216 CNV gain 21841781
nsv828938 CNV gain 20364138
nsv828939 CNV loss 20364138
nsv828943 CNV loss 20364138
nsv834128 CNV loss 17160897
nsv834129 CNV loss 17160897
nsv953023 CNV deletion 24416366

Variation tolerance for GP1BB Gene

Gene Damage Index Score: 1.03; 21.13% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GP1BB Gene

Human Gene Mutation Database (HGMD)
GP1BB
SNPedia medical, phenotypic, and genealogical associations of SNPs for
GP1BB

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GP1BB Gene

Disorders for GP1BB Gene

MalaCards: The human disease database

(15) MalaCards diseases for GP1BB Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search GP1BB in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

GP1BB_HUMAN
  • Bernard-Soulier syndrome (BSS) [MIM:231200]: A coagulation disorder characterized by a prolonged bleeding time, unusually large platelets, thrombocytopenia, and impaired prothrombin consumption. {ECO:0000269 PubMed:9116284}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Genatlas disease for GP1BB Gene

Bernard-Soulier syndrome

Additional Disease Information for GP1BB

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with GP1BB: view

Publications for GP1BB Gene

  1. Application of a diagnostic algorithm for inherited thrombocytopenias to 46 consecutive patients. (PMID: 15477207) Noris P … Balduini CL (Haematologica 2004) 3 23 41 54
  2. Missense mutations of the glycoprotein (GP) Ib beta gene impairing the GPIb alpha/beta disulfide linkage in a family with giant platelet disorder. (PMID: 9116284) Kunishima S … Naoe T (Blood 1997) 3 4 23 54
  3. Complementary DNA cloning of the alternatively expressed endothelial cell glycoprotein Ib beta (GPIb beta) and localization of the GPIb beta gene to chromosome 22. (PMID: 8200976) Kelly MD … Konkle BA (The Journal of clinical investigation 1994) 3 4 23 54
  4. Structural characterization and chromosomal location of the gene encoding human platelet glycoprotein Ib beta. (PMID: 8021244) Yagi M … Roth GJ (The Journal of biological chemistry 1994) 3 4 23 54
  5. Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera. (PMID: 21908432) McEwan PA … Emsley J (Blood 2011) 3 4 54

Products for GP1BB Gene

Sources for GP1BB Gene