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Aliases for GOLGA8T Gene

Aliases for GOLGA8T Gene

  • Golgin A8 Family Member T 2 3 5
  • Golgin Subfamily A Member 8T 3 4
  • Golgin A8 Family, Member T 2

External Ids for GOLGA8T Gene

Previous GeneCards Identifiers for GOLGA8T Gene

  • GC15P030431

Summaries for GOLGA8T Gene

GeneCards Summary for GOLGA8T Gene

GOLGA8T (Golgin A8 Family Member T) is a Protein Coding gene. An important paralog of this gene is GOLGA8K.

Additional gene information for GOLGA8T Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA8T Gene

Genomics for GOLGA8T Gene

GeneHancer (GH) Regulatory Elements for GOLGA8T Gene

Promoters and enhancers for GOLGA8T Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J030136 Enhancer 0.2 Ensembl 600.7 +1.7 1652 0.8 GOLGA8T GC15P030146
GH15J030075 Enhancer 0.7 Ensembl ENCODE 5 -59.9 -59885 0.5 CTCF ZNF384 RAD21 SMC3 ZNF654 PIR34680 PIR45579 GOLGA8T PIRC62
GH15J030130 Enhancer 0.3 Ensembl 0.7 -4.9 -4948 0.4 CTCF GOLGA8T ENSG00000207432 ULK4P3
GH15J030143 Enhancer 0.2 Ensembl 0.4 +8.4 8351 0.2 RN7SL469P GC15P030146 GOLGA8T
GH15J030119 Enhancer 0.2 Ensembl 0.4 -15.6 -15648 0.6 ENSG00000207432 ULK4P3 GOLGA8T
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA8T on UCSC Golden Path with GeneCards custom track

Genomic Locations for GOLGA8T Gene

Genomic Locations for GOLGA8T Gene
chr15:30,135,149-30,147,192
(GRCh38/hg38)
Size:
12,044 bases
Orientation:
Plus strand
chr15:30,427,352-30,439,395
(GRCh37/hg19)
Size:
12,044 bases
Orientation:
Plus strand

Genomic View for GOLGA8T Gene

Genes around GOLGA8T on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8T Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8T Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA8T Gene

Proteins for GOLGA8T Gene

  • Protein details for GOLGA8T Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BQL2-GOG8T_HUMAN
    Recommended name:
    Golgin subfamily A member 8T
    Protein Accession:
    H3BQL2

    Protein attributes for GOLGA8T Gene

    Size:
    631 amino acids
    Molecular mass:
    71644 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA8T Gene

Post-translational modifications for GOLGA8T Gene

No Post-translational modifications

Other Protein References for GOLGA8T Gene

No data available for DME Specific Peptides for GOLGA8T Gene

Domains & Families for GOLGA8T Gene

Gene Families for GOLGA8T Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA8T Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

H3BQL2

UniProtKB/Swiss-Prot:

GOG8T_HUMAN :
  • Belongs to the GOLGA8 family.
Family:
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8T: view

No data available for Suggested Antigen Peptide Sequences for GOLGA8T Gene

Function for GOLGA8T Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA8T Gene

Localization for GOLGA8T Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA8T gene
Compartment Confidence
golgi apparatus 3

Gene Ontology (GO) - Cellular Components for GOLGA8T Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000137 Golgi cis cisterna IBA 21873635
GO:0005794 Golgi apparatus IBA 21873635
GO:0005801 cis-Golgi network IBA 21873635
GO:0032580 Golgi cisterna membrane IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8T: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA8T Gene

Pathways & Interactions for GOLGA8T Gene

PathCards logo

SuperPathways for GOLGA8T Gene

No Data Available

Interacting Proteins for GOLGA8T Gene

Gene Ontology (GO) - Biological Process for GOLGA8T Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007030 Golgi organization IBA 21873635
GO:0051225 NOT spindle assembly IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8T: view

No data available for Pathways by source and SIGNOR curated interactions for GOLGA8T Gene

Drugs & Compounds for GOLGA8T Gene

No Compound Related Data Available

Transcripts for GOLGA8T Gene

mRNA/cDNA for GOLGA8T Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for GOLGA8T Gene

Golgin A8 family, member T:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8T Gene

No ASD Table

Relevant External Links for GOLGA8T Gene

GeneLoc Exon Structure for
GOLGA8T
ECgene alternative splicing isoforms for
GOLGA8T

Expression for GOLGA8T Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GOLGA8T Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8T Gene

This gene is overexpressed in Testis (x10.9).

NURSA nuclear receptor signaling pathways regulating expression of GOLGA8T Gene:

GOLGA8T

SOURCE GeneReport for Unigene cluster for GOLGA8T Gene:

Hs.727141
genes like me logo Genes that share expression patterns with GOLGA8T: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8T Gene

Orthologs for GOLGA8T Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8T Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 94 (a)
ManyToMany
-- 35
  • 91 (a)
ManyToMany
-- 35
  • 91 (a)
ManyToMany
-- 35
  • 89 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 29 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Golga2 35
  • 28 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 28 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 27 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 26 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 23 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 22 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii golga2 35
  • 17 (a)
OneToMany
Species where no ortholog for GOLGA8T was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA8T Gene

ENSEMBL:
Gene Tree for GOLGA8T (if available)
TreeFam:
Gene Tree for GOLGA8T (if available)

Paralogs for GOLGA8T Gene

Variants for GOLGA8T Gene

Sequence variations from dbSNP and Humsavar for GOLGA8T Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000178690 -- 30,143,324(+) A/T intron_variant
rs1000397584 -- 30,142,507(+) C/G/T intron_variant
rs1000510222 -- 30,146,642(+) A/T 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000728607 -- 30,145,942(+) G/A 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant
rs1001622576 -- 30,142,089(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8T Gene

Variant ID Type Subtype PubMed ID
dgv2495n100 CNV loss 25217958
dgv2496n100 CNV gain 25217958
dgv2497n100 CNV loss 25217958
dgv2498n100 CNV gain+loss 25217958
dgv2499n100 CNV loss 25217958
dgv2500n100 CNV gain+loss 25217958
dgv2538n100 CNV loss 25217958
dgv2542n100 CNV loss 25217958
dgv2543n100 CNV gain 25217958
dgv2544n100 CNV gain+loss 25217958
dgv2546n100 CNV loss 25217958
dgv2547n100 CNV loss 25217958
dgv2548n100 CNV loss 25217958
dgv30n68 CNV gain+loss 17160897
dgv42e203 CNV gain+loss 21179565
dgv4417n54 CNV loss 21841781
dgv4446n54 CNV loss 21841781
esv1000078 CNV gain 20482838
esv1008245 CNV gain 20482838
esv2751526 CNV loss 17911159
esv2751527 CNV gain 17911159
esv2760022 CNV gain+loss 17122850
esv2760023 CNV gain+loss 17122850
esv2760365 CNV gain+loss 21179565
esv2761877 CNV gain+loss 21179565
esv33337 CNV gain+loss 17666407
esv3636024 CNV loss 21293372
esv3892661 CNV gain 25118596
nsv1039798 CNV gain 25217958
nsv1040151 CNV gain+loss 25217958
nsv1040778 CNV loss 25217958
nsv1049639 CNV gain+loss 25217958
nsv1146340 CNV duplication 26484159
nsv1148560 OTHER inversion 26484159
nsv1151559 CNV duplication 26484159
nsv1160250 CNV duplication 26073780
nsv1160251 CNV deletion 26073780
nsv1160252 CNV deletion 26073780
nsv1160277 CNV duplication 26073780
nsv428300 CNV loss 18775914
nsv428302 CNV gain+loss 18775914
nsv433433 CNV gain 18776910
nsv517740 CNV gain+loss 19592680
nsv518720 CNV gain 19592680
nsv568719 CNV loss 21841781
nsv568864 CNV loss 21841781
nsv821679 CNV gain 15273396
nsv821681 CNV gain 15273396
nsv832946 CNV gain+loss 17160897
nsv832957 CNV gain+loss 17160897
nsv9232 CNV gain+loss 18304495
nsv9238 CNV gain+loss 18304495
nsv976911 CNV duplication 23825009
nsv977693 CNV duplication 23825009

Variation tolerance for GOLGA8T Gene

Gene Damage Index Score: 3.45; 54.76% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA8T Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA8T

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA8T Gene

Disorders for GOLGA8T Gene

Additional Disease Information for GOLGA8T

No disorders were found for GOLGA8T Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8T Gene

Publications for GOLGA8T Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 58
  2. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 4 58

Products for GOLGA8T Gene

Sources for GOLGA8T Gene

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