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Aliases for GOLGA8S Gene

Aliases for GOLGA8S Gene

  • Golgin A8 Family Member S 2 3 5
  • Golgin Subfamily A Member 8S 3 4
  • Golgin A8 Family, Member S 2

External Ids for GOLGA8S Gene

Previous GeneCards Identifiers for GOLGA8S Gene

  • GC15P023842
  • GC15P023878
  • GC15P023909
  • GC15P023861
  • GC15P023949
  • GC15P024200
  • GC15P023981
  • GC15P024014
  • GC15P024040
  • GC15P024068
  • GC15P024094
  • GC15P024121
  • GC15P024150
  • GC15P024174

Summaries for GOLGA8S Gene

GeneCards Summary for GOLGA8S Gene

GOLGA8S (Golgin A8 Family Member S) is a Protein Coding gene. An important paralog of this gene is GOLGA8G.

Additional gene information for GOLGA8S Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA8S Gene

Genomics for GOLGA8S Gene

GeneHancer (GH) Regulatory Elements for GOLGA8S Gene

Promoters and enhancers for GOLGA8S Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J023363 Enhancer 0.2 Ensembl 0.4 +9.2 9153 0.2 RN7SL536P LOC105370726 GC15P024259 GOLGA8S
GH15J023341 Enhancer 0.2 Ensembl 0.4 -12.4 -12447 1.4 LOC105376698 ENSG00000260399 GOLGA8S
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA8S on UCSC Golden Path with GeneCards custom track

Genomic Locations for GOLGA8S Gene

Genomic Locations for GOLGA8S Gene
chr15:23,354,748-23,368,324
(GRCh38/hg38)
Size:
13,577 bases
Orientation:
Plus strand
chr15:23,599,895-23,613,471
(GRCh37/hg19)
Size:
13,577 bases
Orientation:
Plus strand

Genomic View for GOLGA8S Gene

Genes around GOLGA8S on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8S Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8S Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA8S Gene

Proteins for GOLGA8S Gene

  • Protein details for GOLGA8S Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BPF8-GOG8S_HUMAN
    Recommended name:
    Golgin subfamily A member 8S
    Protein Accession:
    H3BPF8

    Protein attributes for GOLGA8S Gene

    Size:
    625 amino acids
    Molecular mass:
    70417 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA8S Gene

Post-translational modifications for GOLGA8S Gene

No Post-translational modifications

Other Protein References for GOLGA8S Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA8S Gene

Domains & Families for GOLGA8S Gene

Gene Families for GOLGA8S Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA8S Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

H3BPF8

UniProtKB/Swiss-Prot:

GOG8S_HUMAN :
  • Belongs to the GOLGA8 family.
Family:
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8S: view

No data available for Suggested Antigen Peptide Sequences for GOLGA8S Gene

Function for GOLGA8S Gene

Phenotypes From GWAS Catalog for GOLGA8S Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA8S Gene

Localization for GOLGA8S Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA8S gene
Compartment Confidence
golgi apparatus 3

Gene Ontology (GO) - Cellular Components for GOLGA8S Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000137 Golgi cis cisterna IBA 21873635
GO:0005794 Golgi apparatus IBA 21873635
GO:0005801 cis-Golgi network IBA 21873635
GO:0032580 Golgi cisterna membrane IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8S: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA8S Gene

Pathways & Interactions for GOLGA8S Gene

PathCards logo

SuperPathways for GOLGA8S Gene

No Data Available

Interacting Proteins for GOLGA8S Gene

Gene Ontology (GO) - Biological Process for GOLGA8S Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007030 Golgi organization IBA 21873635
GO:0051225 NOT spindle assembly IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8S: view

No data available for Pathways by source and SIGNOR curated interactions for GOLGA8S Gene

Drugs & Compounds for GOLGA8S Gene

No Compound Related Data Available

Transcripts for GOLGA8S Gene

mRNA/cDNA for GOLGA8S Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for GOLGA8S Gene

Golgin A8 family, member S:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8S Gene

No ASD Table

Relevant External Links for GOLGA8S Gene

GeneLoc Exon Structure for
GOLGA8S
ECgene alternative splicing isoforms for
GOLGA8S

Expression for GOLGA8S Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GOLGA8S Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8S Gene

This gene is overexpressed in Testis (x40.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GOLGA8S Gene



NURSA nuclear receptor signaling pathways regulating expression of GOLGA8S Gene:

GOLGA8S

SOURCE GeneReport for Unigene cluster for GOLGA8S Gene:

Hs.528454
genes like me logo Genes that share expression patterns with GOLGA8S: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8S Gene

Orthologs for GOLGA8S Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8S Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 41 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 30 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Golga2 35
  • 29 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 29 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 27 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 27 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 24 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 23 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii golga2 35
  • 18 (a)
OneToMany
Species where no ortholog for GOLGA8S was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA8S Gene

ENSEMBL:
Gene Tree for GOLGA8S (if available)
TreeFam:
Gene Tree for GOLGA8S (if available)

Paralogs for GOLGA8S Gene

Variants for GOLGA8S Gene

Sequence variations from dbSNP and Humsavar for GOLGA8S Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000450653 -- 23,364,700(+) T/C downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant
rs1001237685 -- 23,365,490(+) T/C/G 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant
rs1001336299 -- 23,357,407(+) C/G genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001390241 -- 23,357,683(+) G/A genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001857218 -- 23,365,659(+) A/G 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8S Gene

Variant ID Type Subtype PubMed ID
dgv4331n54 CNV loss 21841781
dgv4332n54 CNV loss 21841781
dgv4333n54 CNV loss 21841781
esv24908 CNV gain+loss 19812545
esv3892623 CNV gain 25118596
nsv1042668 CNV loss 25217958
nsv1075895 CNV duplication 25765185
nsv1148127 CNV duplication 26484159
nsv832930 CNV loss 17160897
nsv9190 CNV loss 18304495
nsv952571 CNV deletion 24416366
nsv984019 CNV duplication 23825009

Variation tolerance for GOLGA8S Gene

Gene Damage Index Score: 19.30; 98.82% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA8S Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA8S

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA8S Gene

Disorders for GOLGA8S Gene

Additional Disease Information for GOLGA8S

No disorders were found for GOLGA8S Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8S Gene

Publications for GOLGA8S Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4 58
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for GOLGA8S Gene

Sources for GOLGA8S Gene

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