Free for academic non-profit institutions. Other users need a Commercial license

Aliases for GOLGA8M Gene

Aliases for GOLGA8M Gene

  • Golgin A8 Family Member M 2 3 5
  • Golgin Subfamily A Member 8M 3 4
  • Putative Golgin Subfamily A Member 6-Like Protein 7 3
  • Golgin A8 Family, Member M 2

External Ids for GOLGA8M Gene

Previous GeneCards Identifiers for GOLGA8M Gene

  • GC15M028962

Summaries for GOLGA8M Gene

GeneCards Summary for GOLGA8M Gene

GOLGA8M (Golgin A8 Family Member M) is a Protein Coding gene. An important paralog of this gene is GOLGA8J.

Additional gene information for GOLGA8M Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA8M Gene

Genomics for GOLGA8M Gene

GeneHancer (GH) Regulatory Elements for GOLGA8M Gene

Promoters and enhancers for GOLGA8M Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J028737 Promoter/Enhancer 1.3 Ensembl ENCODE 607.9 +0.2 183 3.2 NKRF NCOA6 YY1 BACH1 IKZF2 ZNF512 LARP7 PATZ1 ZFX GATAD2B GOLGA8M WHAMMP2 PIR44347 HERC2P9 LOC100419574
GH15J029140 Enhancer 0.7 ENCODE 4.4 -401.6 -401599 0.2 ZNF473 CTCF MLLT1 RAD21 ZBTB8A ZNF143 REST NR2C1 TRIM22 EED NSMCE3 GOLGA8M GC15P029119 GC15P029234 FAM189A1
GH15J029139 Enhancer 0.6 ENCODE 4.7 -401.3 -401289 0.2 ZNF473 CTCF NR2C1 TRIM22 ZBTB17 GABPB1 XRCC5 NR2F6 NSMCE3 GOLGA8M GC15P029119 GC15P029234 FAM189A1
GH15J028736 Promoter 0.5 Ensembl 0.7 +2.1 2083 0.2 WHAMMP2 GOLGA8M PIR45362
GH15J028715 Enhancer 0.2 Ensembl 0.3 +23.1 23083 0.2 PIR45362 GOLGA8M WHAMMP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA8M on UCSC Golden Path with GeneCards custom track

Genomic Locations for GOLGA8M Gene

Genomic Locations for GOLGA8M Gene
chr15:28,698,695-28,738,384
(GRCh38/hg38)
Size:
39,690 bases
Orientation:
Minus strand
chr15:28,947,100-28,983,530
(GRCh37/hg19)
Size:
36,431 bases
Orientation:
Minus strand

Genomic View for GOLGA8M Gene

Genes around GOLGA8M on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8M Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8M Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA8M Gene

Proteins for GOLGA8M Gene

  • Protein details for GOLGA8M Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BSY2-GOG8M_HUMAN
    Recommended name:
    Golgin subfamily A member 8M
    Protein Accession:
    H3BSY2
    Secondary Accessions:
    • A6NCM5
    • F8WBD5

    Protein attributes for GOLGA8M Gene

    Size:
    632 amino acids
    Molecular mass:
    71498 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for GOLGA8M Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GOLGA8M Gene

Post-translational modifications for GOLGA8M Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for GOLGA8M Gene

Domains & Families for GOLGA8M Gene

Gene Families for GOLGA8M Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA8M Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

H3BSY2

UniProtKB/Swiss-Prot:

GOG8M_HUMAN :
  • Belongs to the GOLGA8 family.
Family:
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8M: view

No data available for Suggested Antigen Peptide Sequences for GOLGA8M Gene

Function for GOLGA8M Gene

Phenotypes for GOLGA8M Gene

genes like me logo Genes that share phenotypes with GOLGA8M: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA8M

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GOLGA8M Gene

Localization for GOLGA8M Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA8M gene
Compartment Confidence
golgi apparatus 3

Gene Ontology (GO) - Cellular Components for GOLGA8M Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000137 Golgi cis cisterna IBA 21873635
GO:0005794 Golgi apparatus IBA 21873635
GO:0005801 cis-Golgi network IBA 21873635
GO:0032580 Golgi cisterna membrane IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8M: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA8M Gene

Pathways & Interactions for GOLGA8M Gene

PathCards logo

SuperPathways for GOLGA8M Gene

No Data Available

Interacting Proteins for GOLGA8M Gene

Gene Ontology (GO) - Biological Process for GOLGA8M Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007030 Golgi organization IBA 21873635
GO:0051225 NOT spindle assembly IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8M: view

No data available for Pathways by source and SIGNOR curated interactions for GOLGA8M Gene

Drugs & Compounds for GOLGA8M Gene

No Compound Related Data Available

Transcripts for GOLGA8M Gene

mRNA/cDNA for GOLGA8M Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA8M

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8M Gene

No ASD Table

Relevant External Links for GOLGA8M Gene

GeneLoc Exon Structure for
GOLGA8M
ECgene alternative splicing isoforms for
GOLGA8M

Expression for GOLGA8M Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GOLGA8M Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8M Gene

This gene is overexpressed in Thyroid (x11.0) and Testis (x4.9).

NURSA nuclear receptor signaling pathways regulating expression of GOLGA8M Gene:

GOLGA8M
genes like me logo Genes that share expression patterns with GOLGA8M: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8M Gene

Orthologs for GOLGA8M Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8M Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 94 (a)
ManyToMany
-- 35
  • 92 (a)
ManyToMany
-- 35
  • 92 (a)
ManyToMany
-- 35
  • 90 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 29 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Golga2 35
  • 28 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 27 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 27 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 26 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 23 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 22 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii golga2 35
  • 17 (a)
OneToMany
Species where no ortholog for GOLGA8M was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA8M Gene

ENSEMBL:
Gene Tree for GOLGA8M (if available)
TreeFam:
Gene Tree for GOLGA8M (if available)

Paralogs for GOLGA8M Gene

genes like me logo Genes that share paralogs with GOLGA8M: view

Variants for GOLGA8M Gene

Sequence variations from dbSNP and Humsavar for GOLGA8M Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000084397 -- 28,719,911(-) A/G 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant
rs1000124177 -- 28,701,707(-) G/A 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000278798 -- 28,736,296(-) G/T genic_upstream_transcript_variant, intron_variant
rs1000284632 -- 28,725,725(-) G/A/C genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000353580 -- 28,736,101(-) G/A genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8M Gene

Variant ID Type Subtype PubMed ID
dgv2491n100 CNV gain 25217958
dgv2492n100 CNV gain 25217958
dgv2493n100 CNV loss 25217958
dgv725e212 CNV loss 25503493
esv25177 CNV gain 19812545
esv2749506 CNV deletion 23290073
esv2760021 CNV gain+loss 17122850
nsv1036106 CNV gain+loss 25217958
nsv1036406 CNV gain 25217958
nsv1040778 CNV loss 25217958
nsv1148560 OTHER inversion 26484159
nsv428299 CNV loss 18775914
nsv469678 CNV gain 16826518
nsv471678 CNV loss 15918152
nsv568662 CNV gain 21841781
nsv832942 CNV gain 17160897
nsv977684 CNV duplication 23825009

Variation tolerance for GOLGA8M Gene

Gene Damage Index Score: 22.78; 99.47% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA8M Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA8M

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA8M Gene

Disorders for GOLGA8M Gene

Additional Disease Information for GOLGA8M

No disorders were found for GOLGA8M Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8M Gene

Publications for GOLGA8M Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4 58
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 58
  3. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E … Simpson AJ (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 58

Products for GOLGA8M Gene

Sources for GOLGA8M Gene

Content
Loading form....