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Aliases for GOLGA8K Gene

Aliases for GOLGA8K Gene

  • Golgin A8 Family Member K 2 3 5
  • Golgin Subfamily A Member 8K 3 3 4
  • Putative Golgin Subfamily A Member 8I-Like 3
  • Golgin A8 Family, Member K 2

External Ids for GOLGA8K Gene

Previous GeneCards Identifiers for GOLGA8K Gene

  • GC15M032709
  • GC15M032714
  • GC15M032724

Summaries for GOLGA8K Gene

GeneCards Summary for GOLGA8K Gene

GOLGA8K (Golgin A8 Family Member K) is a Protein Coding gene. An important paralog of this gene is GOLGA8T.

Additional gene information for GOLGA8K Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA8K Gene

Genomics for GOLGA8K Gene

GeneHancer (GH) Regulatory Elements for GOLGA8K Gene

Promoters and enhancers for GOLGA8K Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J032401 Enhancer 0.2 Ensembl 600.7 +1.6 1591 0.6 GOLGA8K GC15M032396 ENSG00000215304
GH15J032408 Enhancer 0.2 Ensembl 0.7 -4.9 -4908 0.4 GOLGA8K PIRC65 ULK4P1 ENSG00000215304
GH15J032418 Enhancer 0.2 Ensembl 0.4 -15.9 -15909 0.8 PIRC65 ULK4P1 ENSG00000215304 GOLGA8K
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA8K on UCSC Golden Path with GeneCards custom track

Genomic Locations for GOLGA8K Gene

Genomic Locations for GOLGA8K Gene
chr15:32,389,585-32,403,292
(GRCh38/hg38)
Size:
13,708 bases
Orientation:
Minus strand
chr15:32,684,890-32,695,493
(GRCh37/hg19)
Size:
10,604 bases
Orientation:
Minus strand

Genomic View for GOLGA8K Gene

Genes around GOLGA8K on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8K Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8K Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA8K Gene

Proteins for GOLGA8K Gene

  • Protein details for GOLGA8K Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    D6RF30-GOG8K_HUMAN
    Recommended name:
    Golgin subfamily A member 8K
    Protein Accession:
    D6RF30

    Protein attributes for GOLGA8K Gene

    Size:
    607 amino acids
    Molecular mass:
    68878 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA8K Gene

Post-translational modifications for GOLGA8K Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA8K Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA8K Gene

Domains & Families for GOLGA8K Gene

Gene Families for GOLGA8K Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA8K Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

D6RF30

UniProtKB/Swiss-Prot:

GOG8K_HUMAN :
  • Belongs to the GOLGA8 family.
Family:
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8K: view

No data available for Suggested Antigen Peptide Sequences for GOLGA8K Gene

Function for GOLGA8K Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA8K

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA8K Gene

Localization for GOLGA8K Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA8K gene
Compartment Confidence
golgi apparatus 3

Gene Ontology (GO) - Cellular Components for GOLGA8K Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000137 Golgi cis cisterna IBA 21873635
GO:0005794 Golgi apparatus IBA 21873635
GO:0005801 cis-Golgi network IBA 21873635
GO:0032580 Golgi cisterna membrane IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8K: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA8K Gene

Pathways & Interactions for GOLGA8K Gene

PathCards logo

SuperPathways for GOLGA8K Gene

No Data Available

Interacting Proteins for GOLGA8K Gene

Gene Ontology (GO) - Biological Process for GOLGA8K Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007030 Golgi organization IBA 21873635
GO:0051225 NOT spindle assembly IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8K: view

No data available for Pathways by source and SIGNOR curated interactions for GOLGA8K Gene

Drugs & Compounds for GOLGA8K Gene

No Compound Related Data Available

Transcripts for GOLGA8K Gene

mRNA/cDNA for GOLGA8K Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for GOLGA8K Gene

Golgin A8 family, member K:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA8K

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8K Gene

No ASD Table

Relevant External Links for GOLGA8K Gene

GeneLoc Exon Structure for
GOLGA8K
ECgene alternative splicing isoforms for
GOLGA8K

Expression for GOLGA8K Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GOLGA8K Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8K Gene

This gene is overexpressed in Testis (x6.5).

NURSA nuclear receptor signaling pathways regulating expression of GOLGA8K Gene:

GOLGA8K

SOURCE GeneReport for Unigene cluster for GOLGA8K Gene:

Hs.649690
genes like me logo Genes that share expression patterns with GOLGA8K: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8K Gene

Orthologs for GOLGA8K Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8K Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 94 (a)
ManyToMany
-- 35
  • 91 (a)
ManyToMany
-- 35
  • 91 (a)
ManyToMany
-- 35
  • 88 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 28 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Golga2 35
  • 28 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 27 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 27 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 26 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 23 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 21 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii golga2 35
  • 17 (a)
OneToMany
Species where no ortholog for GOLGA8K was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA8K Gene

ENSEMBL:
Gene Tree for GOLGA8K (if available)
TreeFam:
Gene Tree for GOLGA8K (if available)

Paralogs for GOLGA8K Gene

Variants for GOLGA8K Gene

Sequence variations from dbSNP and Humsavar for GOLGA8K Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000746125 -- 32,401,168(-) G/A/C intron_variant
rs1000798557 -- 32,402,296(-) C/G/T intron_variant
rs1001526367 -- 32,404,941(-) C/T upstream_transcript_variant
rs1001853634 -- 32,398,702(-) G/C intron_variant
rs1001906004 -- 32,398,917(-) A/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8K Gene

Variant ID Type Subtype PubMed ID
dgv2538n100 CNV loss 25217958
dgv2542n100 CNV loss 25217958
dgv2543n100 CNV gain 25217958
dgv2544n100 CNV gain+loss 25217958
dgv2546n100 CNV loss 25217958
dgv2547n100 CNV loss 25217958
dgv2548n100 CNV loss 25217958
dgv30n68 CNV gain+loss 17160897
dgv4446n54 CNV loss 21841781
esv1000078 CNV gain 20482838
esv2760023 CNV gain+loss 17122850
esv2760365 CNV gain+loss 21179565
esv2761877 CNV gain+loss 21179565
esv33337 CNV gain+loss 17666407
esv3892661 CNV gain 25118596
nsv1143774 CNV deletion 24896259
nsv1146340 CNV duplication 26484159
nsv1160277 CNV duplication 26073780
nsv428302 CNV gain+loss 18775914
nsv433433 CNV gain 18776910
nsv517740 CNV gain+loss 19592680
nsv568864 CNV loss 21841781
nsv821681 CNV gain 15273396
nsv832957 CNV gain+loss 17160897
nsv9238 CNV gain+loss 18304495
nsv977693 CNV duplication 23825009

Variation tolerance for GOLGA8K Gene

Gene Damage Index Score: 7.77; 83.28% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA8K Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA8K

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA8K Gene

Disorders for GOLGA8K Gene

Additional Disease Information for GOLGA8K

No disorders were found for GOLGA8K Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8K Gene

Publications for GOLGA8K Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4 58
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for GOLGA8K Gene

Sources for GOLGA8K Gene

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