Aliases for GOLGA8J Gene

Aliases for GOLGA8J Gene

  • Golgin A8 Family Member J 2 3 5
  • Golgin Subfamily A Member 8J 3 4
  • Golgin Subfamily A Member 8-Like Protein 3 3
  • Golgin A8 Family, Member J 2
  • GOLGA8J 5

External Ids for GOLGA8J Gene

Previous GeneCards Identifiers for GOLGA8J Gene

  • GC15P030377

Summaries for GOLGA8J Gene

GeneCards Summary for GOLGA8J Gene

GOLGA8J (Golgin A8 Family Member J) is a Protein Coding gene. An important paralog of this gene is GOLGA8K.

Additional gene information for GOLGA8J Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GOLGA8J Gene

Genomics for GOLGA8J Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for GOLGA8J Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J030081 Enhancer 0.3 Ensembl 600.7 -1.5 -1528 0.2 MAFK GOLGA8J GOLGA8T piR-41681 TJP1
GH15J030084 Enhancer 0.2 Ensembl 600.7 +1.9 1873 1 GOLGA8J NONHSAG016399.2-001 piR-30673-009 piR-32753-001 piR-31561-001 piR-34638-009 piR-51577-003 GOLGA8T
GH15J030083 Enhancer 0.2 Ensembl 600.7 +1.0 973 0.4 GOLGA8J NONHSAG016399.2-001 piR-31561-001 GOLGA8T
GH15J030103 Promoter 1 Ensembl CraniofacialAtlas 0.4 +21.4 21373 2 ZNF692 ZNF341 ZBTB26 ZNF335 ZNF664 REST DNM1P28 ULK4P3 lnc-GOLGA8T-3 ENSG00000207432 GOLGA8J GOLGA8T
GH15J030063 Enhancer 0.8 Ensembl ENCODE 0.4 -18.2 -18152 3.3 ZNF629 ZBTB44 CEBPB ZSCAN5C EP300 ZFHX2 TCF7L2 ATF4 ZNF366 ZNF843 ENSG00000229389 KR153194-055 lnc-TJP1-2 ENSG00000259647 GOLGA8J TJP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA8J on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GOLGA8J

Genomic Locations for GOLGA8J Gene

Genomic Locations for GOLGA8J Gene
chr15:30,082,628-30,096,711
(GRCh38/hg38)
Size:
14,084 bases
Orientation:
Plus strand
chr15:30,375,158-30,385,702
(GRCh37/hg19)
Size:
10,545 bases
Orientation:
Plus strand

Genomic View for GOLGA8J Gene

Genes around GOLGA8J on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8J Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8J Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA8J Gene

Proteins for GOLGA8J Gene

  • Protein details for GOLGA8J Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NMD2-GOG8J_HUMAN
    Recommended name:
    Golgin subfamily A member 8J
    Protein Accession:
    A6NMD2
    Secondary Accessions:
    • H3BRU0

    Protein attributes for GOLGA8J Gene

    Size:
    632 amino acids
    Molecular mass:
    71775 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA8J Gene

Post-translational modifications for GOLGA8J Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA8J Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA8J Gene

Domains & Families for GOLGA8J Gene

Gene Families for GOLGA8J Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA8J Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GOLGA8J Gene

GenScript: Design optimal peptide antigens:
  • Golgin subfamily A member 8J (GOG8J_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A6NMD2

UniProtKB/Swiss-Prot:

GOG8J_HUMAN :
  • Belongs to the GOLGA8 family.
Family:
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8J: view

Function for GOLGA8J Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA8J

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GOLGA8J Gene

Localization for GOLGA8J Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA8J gene
Compartment Confidence
golgi apparatus 3
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for GOLGA8J Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000137 Golgi cis cisterna IBA 21873635
GO:0005794 Golgi apparatus IBA 21873635
GO:0005801 cis-Golgi network IBA 21873635
GO:0032580 Golgi cisterna membrane IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8J: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA8J Gene

Pathways & Interactions for GOLGA8J Gene

PathCards logo

SuperPathways for GOLGA8J Gene

No Data Available

Interacting Proteins for GOLGA8J Gene

Gene Ontology (GO) - Biological Process for GOLGA8J Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007030 Golgi organization IBA 21873635
GO:0051225 NOT spindle assembly IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8J: view

No data available for Pathways by source and SIGNOR curated interactions for GOLGA8J Gene

Drugs & Compounds for GOLGA8J Gene

No Compound Related Data Available

Transcripts for GOLGA8J Gene

mRNA/cDNA for GOLGA8J Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA8J

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8J Gene

No ASD Table

Relevant External Links for GOLGA8J Gene

GeneLoc Exon Structure for
GOLGA8J

Expression for GOLGA8J Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GOLGA8J Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8J Gene

This gene is overexpressed in Testis (x26.7).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GOLGA8J

SOURCE GeneReport for Unigene cluster for GOLGA8J Gene:

Hs.574257
genes like me logo Genes that share expression patterns with GOLGA8J: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8J Gene

Orthologs for GOLGA8J Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8J Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 94 (a)
ManyToMany
-- 31
  • 92 (a)
ManyToMany
-- 31
  • 91 (a)
ManyToMany
-- 31
  • 89 (a)
ManyToMany
Cow
(Bos Taurus)
Mammalia -- 31
  • 28 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Golga2 31
  • 28 (a)
OneToMany
Dog
(Canis familiaris)
Mammalia -- 31
  • 27 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 26 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 25 (a)
OneToMany
Chicken
(Gallus gallus)
Aves -- 31
  • 23 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 21 (a)
OneToMany
Zebrafish
(Danio rerio)
Actinopterygii golga2 31
  • 17 (a)
OneToMany
Species where no ortholog for GOLGA8J was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for GOLGA8J Gene

ENSEMBL:
Gene Tree for GOLGA8J (if available)
TreeFam:
Gene Tree for GOLGA8J (if available)

Paralogs for GOLGA8J Gene

Variants for GOLGA8J Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GOLGA8J Gene

SNP ID Clinical significance and condition Chr 15 pos Variation AA Info Type
771194 Benign: not provided 30,093,429(+) A/C MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for GOLGA8J Gene

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8J Gene

Variant ID Type Subtype PubMed ID
dgv2403n100 CNV gain 25217958
dgv2405n100 CNV gain+loss 25217958
dgv2406n100 CNV gain 25217958
dgv2407n100 CNV gain+loss 25217958
dgv2408n100 CNV loss 25217958
dgv2409n100 CNV loss 25217958
dgv2410n100 CNV gain 25217958
dgv2495n100 CNV loss 25217958
dgv2496n100 CNV gain 25217958
dgv2497n100 CNV loss 25217958
dgv2498n100 CNV gain+loss 25217958
dgv2499n100 CNV loss 25217958
dgv2500n100 CNV gain+loss 25217958
dgv42e203 CNV gain+loss 21179565
dgv4318n54 CNV gain 21841781
dgv4417n54 CNV loss 21841781
dgv708e212 CNV loss 25503493
dgv709e212 CNV gain 25503493
esv1008245 CNV gain 20482838
esv2474417 CNV loss 19546169
esv2751526 CNV loss 17911159
esv2751527 CNV gain 17911159
esv2760022 CNV gain+loss 17122850
esv28050 CNV gain+loss 19812545
esv3569265 CNV gain 25503493
esv3636024 CNV loss 21293372
esv3892626 CNV gain+loss 25118596
nsv1035969 CNV loss 25217958
nsv1039798 CNV gain 25217958
nsv1040151 CNV gain+loss 25217958
nsv1040546 CNV gain 25217958
nsv1040778 CNV loss 25217958
nsv1041383 CNV loss 25217958
nsv1049639 CNV gain+loss 25217958
nsv1136191 CNV deletion 24896259
nsv1148560 OTHER inversion 26484159
nsv1150333 CNV duplication 26484159
nsv1160250 CNV duplication 26073780
nsv428300 CNV loss 18775914
nsv433429 CNV gain 18776910
nsv433430 CNV gain 18776910
nsv511042 OTHER inversion 20534489
nsv518720 CNV gain 19592680
nsv568235 CNV loss 21841781
nsv832927 CNV gain 17160897
nsv832928 CNV gain 17160897
nsv832946 CNV gain+loss 17160897
nsv9232 CNV gain+loss 18304495
nsv952594 CNV duplication 24416366
nsv974523 CNV duplication 23825009
nsv974545 CNV duplication 23825009

Variation tolerance for GOLGA8J Gene

Gene Damage Index Score: 5.32; 70.60% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA8J Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA8J

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA8J Gene

Disorders for GOLGA8J Gene

No disorders were found for GOLGA8J Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8J Gene

Publications for GOLGA8J Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4
  2. E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. (PMID: 29676528) Khanna R … Parnaik VK (The FEBS journal 2018) 3
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3

Products for GOLGA8J Gene

Sources for GOLGA8J Gene