Aliases for GOLGA8H Gene

Aliases for GOLGA8H Gene

  • Golgin A8 Family Member H 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 6-Like 11 2 3
  • Golgin Subfamily A Member 8H 3 4
  • Golgin Subfamily A Member 8-Like Protein 1 3
  • Golgin A8 Family, Member H 2
  • GOLGA6L11 3

External Ids for GOLGA8H Gene

Previous GeneCards Identifiers for GOLGA8H Gene

  • GC15P030902
  • GC15P030903
  • GC15P030604
  • GC15P030546
  • GC15P030660
  • GC15P030661
  • GC15P030547
  • GC15P030573
  • GC15P030594
  • GC15P030633
  • GC15P030657
  • GC15P030656

Summaries for GOLGA8H Gene

GeneCards Summary for GOLGA8H Gene

GOLGA8H (Golgin A8 Family Member H) is a Protein Coding gene. An important paralog of this gene is GOLGA8T.

Additional gene information for GOLGA8H Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GOLGA8H Gene

Genomics for GOLGA8H Gene

GeneHancer (GH) Regulatory Elements for GOLGA8H Gene

Promoters and enhancers for GOLGA8H Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA8H on UCSC Golden Path with GeneCards custom track

Genomic Locations for GOLGA8H Gene

Genomic Locations for GOLGA8H Gene
chr15:30,545,870-30,617,827
(GRCh38/hg38)
Size:
71,958 bases
Orientation:
Plus strand
chr15:30,896,233-30,906,859
(GRCh37/hg19)
Size:
10,627 bases
Orientation:
Plus strand

Genomic View for GOLGA8H Gene

Genes around GOLGA8H on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8H Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8H Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA8H Gene

Proteins for GOLGA8H Gene

  • Protein details for GOLGA8H Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CJ92-GOG8H_HUMAN
    Recommended name:
    Golgin subfamily A member 8H
    Protein Accession:
    P0CJ92

    Protein attributes for GOLGA8H Gene

    Size:
    632 amino acids
    Molecular mass:
    71342 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA8H Gene

Post-translational modifications for GOLGA8H Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA8H Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA8H Gene

Domains & Families for GOLGA8H Gene

Gene Families for GOLGA8H Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA8H Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GOLGA8H Gene

GenScript: Design optimal peptide antigens:
  • Golgin subfamily A member 8H (GOG8H_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P0CJ92

UniProtKB/Swiss-Prot:

GOG8H_HUMAN :
  • Belongs to the GOLGA8 family.
Family:
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8H: view

Function for GOLGA8H Gene

Phenotypes From GWAS Catalog for GOLGA8H Gene

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GOLGA8H Gene

Localization for GOLGA8H Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA8H gene
Compartment Confidence
golgi apparatus 3

Gene Ontology (GO) - Cellular Components for GOLGA8H Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000137 Golgi cis cisterna IBA 21873635
GO:0005794 Golgi apparatus IBA 21873635
GO:0005801 cis-Golgi network IBA 21873635
GO:0032580 Golgi cisterna membrane IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8H: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA8H Gene

Pathways & Interactions for GOLGA8H Gene

PathCards logo

SuperPathways for GOLGA8H Gene

No Data Available

Interacting Proteins for GOLGA8H Gene

Gene Ontology (GO) - Biological Process for GOLGA8H Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007030 Golgi organization IBA 21873635
GO:0051225 NOT spindle assembly IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8H: view

No data available for Pathways by source and SIGNOR curated interactions for GOLGA8H Gene

Drugs & Compounds for GOLGA8H Gene

No Compound Related Data Available

Transcripts for GOLGA8H Gene

mRNA/cDNA for GOLGA8H Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8H Gene

No ASD Table

Relevant External Links for GOLGA8H Gene

GeneLoc Exon Structure for
GOLGA8H
ECgene alternative splicing isoforms for
GOLGA8H

Expression for GOLGA8H Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GOLGA8H Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8H Gene

This gene is overexpressed in Testis (x7.2).

NURSA nuclear receptor signaling pathways regulating expression of GOLGA8H Gene:

GOLGA8H
genes like me logo Genes that share expression patterns with GOLGA8H: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8H Gene

Orthologs for GOLGA8H Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8H Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 33
  • 94 (a)
ManyToMany
-- 33
  • 92 (a)
ManyToMany
-- 33
  • 91 (a)
ManyToMany
-- 33
  • 89 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Golga2 33
  • 28 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 33
  • 28 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 33
  • 27 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 33
  • 26 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 33
  • 25 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 33
  • 22 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 33
  • 21 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii golga2 33
  • 17 (a)
OneToMany
Species where no ortholog for GOLGA8H was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA8H Gene

ENSEMBL:
Gene Tree for GOLGA8H (if available)
TreeFam:
Gene Tree for GOLGA8H (if available)

Paralogs for GOLGA8H Gene

Variants for GOLGA8H Gene

Sequence variations from dbSNP and Humsavar for GOLGA8H Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000298908 -- 30,608,062(+) G/A coding_sequence_variant, synonymous_variant
rs1000339122 -- 30,612,590(+) C/G intron_variant
rs1000455211 -- 30,613,099(+) C/A/G/T intron_variant
rs1000559738 -- 30,608,753(+) C/G coding_sequence_variant, missense_variant
rs1000628152 -- 30,607,860(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8H Gene

Variant ID Type Subtype PubMed ID
dgv106n111 OTHER complex 26073780
dgv20e213 CNV loss 24956385
dgv2495n100 CNV loss 25217958
dgv2496n100 CNV gain 25217958
dgv2500n100 CNV gain+loss 25217958
dgv2503n100 CNV loss 25217958
dgv2504n100 CNV gain 25217958
dgv2505n100 CNV loss 25217958
dgv2514n100 CNV loss 25217958
dgv2517n100 CNV loss 25217958
dgv2518n100 CNV gain 25217958
dgv2520n100 CNV loss 25217958
dgv2523n100 CNV gain 25217958
dgv2524n100 CNV loss 25217958
dgv2525n100 CNV loss 25217958
dgv2526n100 CNV loss 25217958
dgv2527n100 CNV loss 25217958
dgv2528n100 CNV loss 25217958
dgv2529n100 CNV gain+loss 25217958
dgv2530n100 CNV gain 25217958
dgv2538n100 CNV loss 25217958
dgv2542n100 CNV loss 25217958
dgv2543n100 CNV gain 25217958
dgv2544n100 CNV gain+loss 25217958
dgv2546n100 CNV loss 25217958
dgv2547n100 CNV loss 25217958
dgv2548n100 CNV loss 25217958
dgv30n68 CNV gain+loss 17160897
dgv42e203 CNV gain+loss 21179565
dgv4417n54 CNV loss 21841781
dgv4425n54 CNV gain 21841781
dgv4446n54 CNV loss 21841781
esv1000078 CNV gain 20482838
esv24159 CNV gain+loss 19812545
esv2751526 CNV loss 17911159
esv2760022 CNV gain+loss 17122850
esv2760023 CNV gain+loss 17122850
esv2760365 CNV gain+loss 21179565
esv2761877 CNV gain+loss 21179565
esv33337 CNV gain+loss 17666407
esv3584688 CNV loss 24956385
esv3892661 CNV gain 25118596
nsv1049195 CNV gain 25217958
nsv1049226 CNV gain+loss 25217958
nsv1049639 CNV gain+loss 25217958
nsv1143774 CNV deletion 24896259
nsv1146340 CNV duplication 26484159
nsv1148560 OTHER inversion 26484159
nsv1160272 CNV duplication 26073780
nsv1160277 CNV duplication 26073780
nsv428300 CNV loss 18775914
nsv428302 CNV gain+loss 18775914
nsv433433 CNV gain 18776910
nsv517740 CNV gain+loss 19592680
nsv518720 CNV gain 19592680
nsv568748 CNV loss 21841781
nsv568864 CNV loss 21841781
nsv821681 CNV gain 15273396
nsv832957 CNV gain+loss 17160897
nsv9232 CNV gain+loss 18304495
nsv9238 CNV gain+loss 18304495
nsv977692 CNV duplication 23825009
nsv977693 CNV duplication 23825009

Variation tolerance for GOLGA8H Gene

Gene Damage Index Score: 7.65; 82.83% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA8H Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA8H

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA8H Gene

Disorders for GOLGA8H Gene

Additional Disease Information for GOLGA8H

No disorders were found for GOLGA8H Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8H Gene

Publications for GOLGA8H Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4 56
  2. A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy. (PMID: 23962720) Speed D … Johnson MR (Human molecular genetics 2014) 3 56
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 56

Products for GOLGA8H Gene

Sources for GOLGA8H Gene