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Aliases for GOLGA8G Gene
Aliases for GOLGA8G Gene
External Ids for GOLGA8G Gene
- HGNC: 25328
- Entrez Gene: 283768
- Ensembl: ENSG00000183629
- UniProtKB: Q08AF8
Previous GeneCards Identifiers for GOLGA8G Gene
- GC15M026565
- GC15M028764
Summaries for GOLGA8G Gene
GeneCards Summary for GOLGA8G Gene
GOLGA8G (Golgin A8 Family Member G) is a Protein Coding gene. Diseases associated with GOLGA8G include Prader-Willi Syndrome. An important paralog of this gene is GOLGA8F.
Additional gene information for GOLGA8G Gene
- HGNC(25328)
- Entrez Gene(283768)
- Ensembl(ENSG00000183629)
- UniProtKB(Q08AF8)
- Open Targets Platform(ENSG00000183629)
- Search for GOLGA8G at DataMed
- Search for GOLGA8G at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GOLGA8G Gene
Genomics for GOLGA8G Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GOLGA8G Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH15J028532 | Promoter | 0.3 | EPDnew | 600.7 | +0.0 | 23 | 0.1 | GOLGA8G lnc-GOLGA8G-1 piR-32966-006 piR-33613-006 piR-31592-006 piR-41940-004 piR-40585-006 piR-48043-006 GOLGA8F | ||
| GH15J028508 | Promoter | 0.4 | Ensembl | 0.4 | +24.3 | 24313 | 1 | POLR2A | ABCB10P4 ENSG00000274814 GOLGA8G GOLGA8F | |
| GH15J028454 | Promoter | 0.4 | CraniofacialAtlas | 0.2 | +78.4 | 78359 | 0.4 | ZBTB33 | ENSG00000260159 lnc-GOLGA8G-2 ENSG00000284628 LOC101059997 GOLGA8F GOLGA8G | |
| GH15J028516 | Enhancer | 0.2 | Ensembl | 0.4 | +16.9 | 16913 | 0.2 | piR-57607-005 ABCB10P4 GOLGA8G GOLGA8F | ||
| GH15J028514 | Enhancer | 0.2 | Ensembl | 0.4 | +17.7 | 17732 | 1 | piR-57607-005 ABCB10P4 GOLGA8G GOLGA8F |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GOLGA8G on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GOLGA8G
- Top Transcription factor binding sites by QIAGEN in the GOLGA8G gene promoter:
-
- AML1a
- AREB6
- Brachyury
- FOXJ2
- FOXJ2 (long isoform)
- HTF
- IRF-2
- MZF-1
- Olf-1
- Roaz
Genomic Locations for GOLGA8G Gene
Genomic Locations for GOLGA8G Gene
- chr15:28,519,611-28,533,014
- (GRCh38/hg38)
- Size:
- 13,404 bases
- Orientation:
- Minus strand
- chr15:28,764,757-28,778,160
- (GRCh37/hg19)
- Size:
- 13,404 bases
- Orientation:
- Minus strand
Genomic View for GOLGA8G Gene
Genes around GOLGA8G on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q13.1 by HGNC
- 15q13.1 by Entrez Gene
- 15q13.1 by Ensembl
GOLGA8G Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GOLGA8G Gene
Proteins for GOLGA8G Gene
-
Protein details for GOLGA8G Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q08AF8-GOG8F_HUMAN
- Recommended name:
- Putative golgin subfamily A member 8F/8G
- Protein Accession:
- Q08AF8
- A4FTY1
- Q1A5X9
- Q8NDK0
Protein attributes for GOLGA8G Gene
- Size:
- 430 amino acids
- Molecular mass:
- 48405 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for GOLGA8G Gene
No Post-translational modifications
Other Protein References for GOLGA8G Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for GOLGA8G
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No data available for DME Specific Peptides for GOLGA8G Gene
Domains & Families for GOLGA8G Gene
Gene Families for GOLGA8G Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for GOLGA8G Gene
- GenScript: Design optimal peptide antigens:
-
- Putative golgin subfamily A member 8F/8G (GOG8F_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q08AF8- Family:
-
- Belongs to the GOLGA8 family.
Function for GOLGA8G Gene
Phenotypes From GWAS Catalog for GOLGA8G Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for GOLGA8G Gene
- GenomeRNAi human phenotypes for GOLGA8G:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for GOLGA8G - Select products 50% OFF >
- * GOLGA8G CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for GOLGA8G
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miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for GOLGA8G - Select products 50% OFF >
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- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GOLGA8G
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA8G Gene
Localization for GOLGA8G Gene
| Compartment | Confidence |
|---|---|
| golgi apparatus | 3 |
| nucleus | 2 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000137 | Golgi cis cisterna | IBA | 21873635 |
| GO:0005794 | Golgi apparatus | IEA,IBA | 21873635 |
| GO:0005801 | cis-Golgi network | IBA | 21873635 |
| GO:0032580 | Golgi cisterna membrane | IBA | 21873635 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA8G Gene
Pathways & Interactions for GOLGA8G Gene
Interacting Proteins for GOLGA8G Gene
Selected Interacting proteins:
Q08AF8-GOG8F_HUMAN
ENSP00000458130
for GOLGA8G Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for GOLGA8G
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007030 | Golgi organization | IBA | 21873635 |
| GO:0051225 | NOT spindle assembly | IBA | 21873635 |
No data available for Pathways by source and SIGNOR curated interactions for GOLGA8G Gene
Transcripts for GOLGA8G Gene
mRNA/cDNA for GOLGA8G Gene
- 4 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000382949 5256 nts (view in UCSC)
- ENST00000524859 5240 nts (view in UCSC)
- ENST00000525590 2009 nts (view in UCSC)
- ENST00000561497 565 nts (view in UCSC)
- ENST00000562627 6093 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for GOLGA8G - Select products 50% OFF >
- * GOLGA8G CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for GOLGA8G
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GOLGA8G
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GOLGA8G
- Browse OriGene Inhibitory RNA Products For GOLGA8G
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Clone Products
- Applied Biological Materials (abm): Clones for GOLGA8G - Select products 50% OFF >
- * GOLGA8G as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GOLGA8G
Relevant External Links for GOLGA8G Gene
- GeneLoc Exon Structure for
- GOLGA8G
Expression for GOLGA8G Gene
mRNA differential expression in normal tissues according to GTEx for GOLGA8G Gene
This gene is overexpressed in Testis (x28.2).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GOLGA8G
SOURCE GeneReport for Unigene cluster for GOLGA8G Gene:
Hs.169639Primer Products
-
OriGene qPCR primer pairs for GOLGA8G
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8G Gene
Orthologs for GOLGA8G Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | -- 31 |
|
ManyToMany | |
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToMany | |
| Mouse (Mus musculus) |
Mammalia | Golga2 31 |
|
OneToMany | |
| Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| Zebrafish (Danio rerio) |
Actinopterygii | golga2 31 |
|
OneToMany |
- Species where no ortholog for GOLGA8G was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Paralogs for GOLGA8G Gene
Paralogs for GOLGA8G Gene
(29) SIMAP similar genes for GOLGA8G Gene using alignment to 1 proteins:
- GOG8F_HUMAN
Variants for GOLGA8G Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2491n100 | CNV | gain | 25217958 |
| dgv2492n100 | CNV | gain | 25217958 |
| dgv725e212 | CNV | loss | 25503493 |
| esv22824 | CNV | gain+loss | 19812545 |
| esv26019 | CNV | gain+loss | 19812545 |
| esv2674813 | CNV | deletion | 23128226 |
| esv2760021 | CNV | gain+loss | 17122850 |
| nsv1052131 | CNV | gain | 25217958 |
| nsv1075896 | CNV | duplication | 25765185 |
| nsv1118554 | CNV | duplication | 24896259 |
| nsv1141260 | CNV | duplication | 24896259 |
| nsv1148060 | CNV | duplication | 26484159 |
| nsv1148560 | OTHER | inversion | 26484159 |
| nsv1150469 | CNV | duplication | 26484159 |
| nsv1152851 | CNV | duplication | 26484159 |
| nsv428299 | CNV | loss | 18775914 |
| nsv433431 | CNV | gain | 18776910 |
| nsv469883 | CNV | gain | 16826518 |
| nsv568662 | CNV | gain | 21841781 |
| nsv832941 | CNV | gain+loss | 17160897 |
| nsv974540 | CNV | duplication | 23825009 |
| nsv976906 | CNV | duplication | 23825009 |
| nsv977790 | CNV | duplication | 23825009 |
Gene Damage Index Score:
1.69;
32.16% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GOLGA8G Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- GOLGA8G
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GOLGA8G Gene
Disorders for GOLGA8G Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| prader-willi syndrome |
|
|
Search GOLGA8G in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for GOLGA8G
No data available for UniProtKB/Swiss-Prot and Genatlas for GOLGA8G Gene
Publications for GOLGA8G Gene
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
- An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders. (PMID: 29892012) Chen S … Yu H (Nature genetics 2018) 3
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3
- Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
- Genomic analysis of the chromosome 15q11-q13 Prader-Willi syndrome region and characterization of transcripts for GOLGA8E and WHCD1L1 from the proximal breakpoint region. (PMID: 18226259) Jiang YH … Beaudet AL (BMC genomics 2008) 4
ExternalLinks
Products for GOLGA8G Gene
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Sources for GOLGA8G Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
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- (27) ASD
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- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
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- (38) dbSNP
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- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
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- (84) COMPARTMENTS
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- (93) PathCards
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- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
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- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
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- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
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- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
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- (148) RNACentral
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- (152) DiseaseEnhancer
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- (154) Biorbyt
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- (156) Mastermind
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- (163) LncBase
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- (165) LNCipedia
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- (178) MirGeneDB