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GOLGA8G Gene(Protein Coding)

Golgin A8 Family Member G

GCID:
GC15M028519
GIFtS:
26
Genes Participants
UDN Logo

Aliases for GOLGA8G Gene

Aliases for GOLGA8G Gene

  • Golgin A8 Family Member G 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 8G 2 3
  • Putative Golgin Subfamily A Member 8F/8G 3
  • Golgin A8 Family, Member G 2
  • GOLGA8F 3

External Ids for GOLGA8G Gene

Previous GeneCards Identifiers for GOLGA8G Gene

  • GC15M026565
  • GC15M028764

Summaries for GOLGA8G Gene

GeneCards Summary for GOLGA8G Gene

GOLGA8G (Golgin A8 Family Member G) is a Protein Coding gene. An important paralog of this gene is GOLGA8F.

Additional gene information for GOLGA8G Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA8G Gene

Genomics for GOLGA8G Gene

GeneHancer (GH) Regulatory Elements for GOLGA8G Gene

Promoters and enhancers for GOLGA8G Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH15J028532 Promoter 0.5 EPDnew 600.7 +0.0 23 0.1 GOLGA8G PIR46343
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA8G on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the GOLGA8G gene promoter:
  • AML1a
  • AREB6
  • Brachyury
  • FOXJ2
  • FOXJ2 (long isoform)
  • HTF
  • IRF-2
  • MZF-1
  • Olf-1
  • Roaz

Genomic Locations for GOLGA8G Gene

Genomic Locations for GOLGA8G Gene
chr15:28,519,611-28,533,014
(GRCh38/hg38)
Size:
13,404 bases
Orientation:
Minus strand
chr15:28,764,757-28,778,160
(GRCh37/hg19)
Size:
13,404 bases
Orientation:
Minus strand

Genomic View for GOLGA8G Gene

Genes around GOLGA8G on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8G Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for GOLGA8G Gene

Proteins for GOLGA8G Gene

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  • Protein details for GOLGA8G Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q08AF8-GOG8F_HUMAN
    Recommended name:
    Putative golgin subfamily A member 8F/8G
    Protein Accession:
    Q08AF8
    Secondary Accessions:
    • A4FTY1
    • Q1A5X9
    • Q8NDK0

    Protein attributes for GOLGA8G Gene

    Size:
    430 amino acids
    Molecular mass:
    48405 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for GOLGA8G Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GOLGA8G Gene

Post-translational modifications for GOLGA8G Gene

No Post-translational modifications

Other Protein References for GOLGA8G Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA8G Gene

Domains & Families for GOLGA8G Gene

Gene Families for GOLGA8G Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA8G Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GOLGA8G Gene

GenScript: Design optimal peptide antigens:
  • Putative golgin subfamily A member 8F/8G (GOG8F_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q08AF8

UniProtKB/Swiss-Prot:

GOG8F_HUMAN :
  • Belongs to the GOLGA8 family.
Family:
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8G: view

Function for GOLGA8G Gene

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  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
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  6. Cell Line

Phenotypes From GWAS Catalog for GOLGA8G Gene

Gene Ontology (GO) - Molecular Function for GOLGA8G Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with GOLGA8G: view

Phenotypes for GOLGA8G Gene

GenomeRNAi human phenotypes for GOLGA8G:
genes like me logo Genes that share phenotypes with GOLGA8G: view

Animal Model Products

CRISPR Products

Clone Products

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No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA8G Gene

Localization for GOLGA8G Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA8G gene
Compartment Confidence
golgi apparatus 3
nucleus 2
cytosol 1

Gene Ontology (GO) - Cellular Components for GOLGA8G Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000137 Golgi cis cisterna IBA 21873635
GO:0005794 Golgi apparatus IBA 21873635
GO:0005801 cis-Golgi network IBA 21873635
GO:0032580 Golgi cisterna membrane IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8G: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA8G Gene

Pathways & Interactions for GOLGA8G Gene

GeneAnalytics - gene set analysis. Cells, Diseases, Pathways, Function and Compounds, relevant to your gene set. Powered by GeneCards
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SuperPathways for GOLGA8G Gene

No Data Available

Interacting Proteins for GOLGA8G Gene

STRING Interaction Network Preview (showing top 5 STRING interactants - click image to see top 25)
https://version11.string-db.org/api/image/network?species=9606&limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000458130%0d9606.ENSP00000225724%0d9606.ENSP00000294179%0d9606.ENSP00000377275%0d9606.ENSP00000444850%0d9606.ENSP00000313869%0d
Selected Interacting proteins: ENSP00000458130 Q08AF8-GOG8F_HUMAN for GOLGA8G Gene via STRING IID

GPS-Prot Interaction Network for GOLGA8G

Gene Ontology (GO) - Biological Process for GOLGA8G Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007030 Golgi organization IBA 21873635
GO:0051225 NOT spindle assembly IBA 21873635
genes like me logo Genes that share ontologies with GOLGA8G: view

No data available for Pathways by source and SIGNOR curated interactions for GOLGA8G Gene

Drugs & Compounds for GOLGA8G Gene

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  1. Drug
GeneAnalytics - gene set analysis. Cells, Diseases, Pathways, Function and Compounds, relevant to your gene set. Powered by GeneCards
No Compound Related Data Available

Transcripts for GOLGA8G Gene

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  2. miRNA
  3. Inhibitory RNA
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mRNA/cDNA for GOLGA8G Gene

(4) REFSEQ mRNAs :
(9) Additional mRNA sequences :
(28) Selected AceView cDNA sequences:
(8) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for GOLGA8G Gene

Golgin A8 family, member G:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for GOLGA8G - Now 50% OFF >
  • * GOLGA8G as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * GOLGA8G tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8G Gene

No ASD Table

Relevant External Links for GOLGA8G Gene

GeneLoc Exon Structure for
GOLGA8G
ECgene alternative splicing isoforms for
GOLGA8G

Expression for GOLGA8G Gene

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  1. Primer
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GeneAnalytics - gene set analysis. Cells, Diseases, Pathways, Function and Compounds, relevant to your gene set. Powered by GeneCards

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GOLGA8G Gene

mRNA expression in normal human tissues for GOLGA8G Gene
mRNA expression by BioGPS for GOLGA8G GenemRNA expression by GTEx for GOLGA8G Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8G Gene

This gene is overexpressed in Testis (x28.2).

NURSA nuclear receptor signaling pathways regulating expression of GOLGA8G Gene:

GOLGA8G

SOURCE GeneReport for Unigene cluster for GOLGA8G Gene:

Hs.169639
genes like me logo Genes that share expression patterns with GOLGA8G: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8G Gene

Orthologs for GOLGA8G Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8G Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia -- 35
  • 52 (a)
 ManyToMany
cow
(Bos Taurus)
 Mammalia -- 35
  • 31 (a)
 OneToMany
mouse
(Mus musculus)
 Mammalia Golga2 35
  • 30 (a)
 OneToMany
dog
(Canis familiaris)
 Mammalia -- 35
  • 28 (a)
 OneToMany
platypus
(Ornithorhynchus anatinus)
 Mammalia -- 35
  • 27 (a)
 OneToMany
oppossum
(Monodelphis domestica)
 Mammalia -- 35
  • 27 (a)
 OneToMany
chicken
(Gallus gallus)
 Aves -- 35
  • 24 (a)
 OneToMany
lizard
(Anolis carolinensis)
 Reptilia -- 35
  • 23 (a)
 OneToMany
zebrafish
(Danio rerio)
 Actinopterygii golga2 35
  • 18 (a)
 OneToMany
Species where no ortholog for GOLGA8G was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA8G Gene

ENSEMBL:
Gene Tree for GOLGA8G (if available)
TreeFam:
Gene Tree for GOLGA8G (if available)

Paralogs for GOLGA8G Gene

Variants for GOLGA8G Gene

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  1. SNP Genotyping and Copy Number Assay
VarElect - NGS phenotyper. Rapid prioritization of variants from NGS data powered by 100+ GeneCards sources

Sequence variations from dbSNP and Humsavar for GOLGA8G Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000122938 -- 28,533,729(-) C/T upstream_transcript_variant
rs1000237674 -- 28,532,845(-) A/G coding_sequence_variant, intron_variant, missense_variant, non_coding_transcript_variant
rs1001337827 -- 28,531,952(-) A/G intron_variant
rs1001450788 -- 28,531,321(-) A/G intron_variant
rs1003122738 -- 28,519,153(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8G Gene

Variant ID Type Subtype PubMed ID
dgv2491n100 CNV gain 25217958
dgv2492n100 CNV gain 25217958
dgv725e212 CNV loss 25503493
esv22824 CNV gain+loss 19812545
esv26019 CNV gain+loss 19812545
esv2674813 CNV deletion 23128226
esv2760021 CNV gain+loss 17122850
nsv1052131 CNV gain 25217958
nsv1075896 CNV duplication 25765185
nsv1118554 CNV duplication 24896259
nsv1141260 CNV duplication 24896259
nsv1148060 CNV duplication 26484159
nsv1148560 OTHER inversion 26484159
nsv1150469 CNV duplication 26484159
nsv1152851 CNV duplication 26484159
nsv428299 CNV loss 18775914
nsv433431 CNV gain 18776910
nsv469883 CNV gain 16826518
nsv568662 CNV gain 21841781
nsv832941 CNV gain+loss 17160897
nsv974540 CNV duplication 23825009
nsv976906 CNV duplication 23825009
nsv977790 CNV duplication 23825009

Variation tolerance for GOLGA8G Gene

Gene Damage Index Score: 1.69; 32.16% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA8G Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA8G

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA8G Gene

Disorders for GOLGA8G Gene

Additional Disease Information for GOLGA8G

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for GOLGA8G Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8G Gene

Publications for GOLGA8G Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 58
  4. Genomic analysis of the chromosome 15q11-q13 Prader-Willi syndrome region and characterization of transcripts for GOLGA8E and WHCD1L1 from the proximal breakpoint region. (PMID: 18226259) Jiang YH … Beaudet AL (BMC genomics 2008) 4 58
  5. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58

ExternalLinks

View latest publications for GOLGA8G gene in Mastermind

Products for GOLGA8G Gene

Sources for GOLGA8G Gene

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