Aliases for GOLGA7B Gene

Aliases for GOLGA7B Gene

  • Golgin A7 Family Member B 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 7B 2 3
  • Golgin Subfamily A Member 7B 3 4
  • BA451M19.3 2 3
  • C10orf132 3 4
  • C10orf133 3 4
  • BA459F3.4 2 3
  • Chromosome 10 Open Reading Frame 133 2
  • Chromosome 10 Open Reading Frame 132 2
  • Golgin A7 Family, Member B 2
  • GOLGA7B 5

External Ids for GOLGA7B Gene

Previous HGNC Symbols for GOLGA7B Gene

  • C10orf133
  • C10orf132

Previous GeneCards Identifiers for GOLGA7B Gene

  • GC10P099599
  • GC10P093235
  • GC10P099609

Summaries for GOLGA7B Gene

GeneCards Summary for GOLGA7B Gene

GOLGA7B (Golgin A7 Family Member B) is a Protein Coding gene. An important paralog of this gene is GOLGA7.

UniProtKB/Swiss-Prot Summary for GOLGA7B Gene

Additional gene information for GOLGA7B Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GOLGA7B Gene

Genomics for GOLGA7B Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for GOLGA7B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J097848 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE dbSUPER 606.6 +1.2 1161 4.4 CREB1 ZBTB33 TARDBP FOXA1 PATZ1 REST EZH2 ZNF600 ZNF341 ATF7 GOLGA7B LINC00866 lnc-CRTAC1-2 lnc-GOLGA7B-1 CRTAC1
GH10J097869 Enhancer 1.2 Ensembl ENCODE dbSUPER 18.9 +19.7 19657 2.2 CTCF PRDM10 ZNF629 ZNF692 FOXA1 ZIC2 PATZ1 REST RAD21 ZNF600 GOLGA7B SFRP5 lnc-GOLGA7B-1 MIR3085 CRTAC1
GH10J097819 Enhancer 0.7 Ensembl dbSUPER 21.7 -28.5 -28542 3 ZIC2 MAFF MAFK ZFHX2 FOS CTCF EGR2 LOC107984260 lnc-GOLGA7B-2 GOLGA7B ZFYVE27 lnc-GOLGA7B-3 SFRP5
GH10J097827 Enhancer 0.6 Ensembl dbSUPER 20.4 -20.8 -20842 3.2 ZIC2 KLF1 EGR2 GATA2 GOLGA7B SFRP5 CRTAC1 ZFYVE27 LOC107984260 lnc-GOLGA7B-2 piR-40459 lnc-GOLGA7B-3 LINC00866
GH10J097837 Enhancer 1.3 Ensembl ENCODE dbSUPER 6.6 -10.9 -10942 6.2 PRDM10 ZNF629 LEF1 IKZF1 CTCF ZNF692 JUND MTA2 MTA1 REST piR-40459 SFRP5 CRTAC1 PYROXD2 GOLGA7B piR-39488-046 piR-56022-052 piR-56088-003 piR-55281-062 LINC00866
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA7B on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GOLGA7B

Top Transcription factor binding sites by QIAGEN in the GOLGA7B gene promoter:
  • c-Myc
  • Max1
  • Meis-1
  • Meis-1a
  • NRSF form 1
  • NRSF form 2

Genomic Locations for GOLGA7B Gene

Genomic Locations for GOLGA7B Gene
21,738 bases
Plus strand
21,342 bases
Plus strand

Genomic View for GOLGA7B Gene

Genes around GOLGA7B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA7B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA7B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA7B Gene

Proteins for GOLGA7B Gene

  • Protein details for GOLGA7B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Golgin subfamily A member 7B
    Protein Accession:
    Secondary Accessions:
    • Q5T4F5

    Protein attributes for GOLGA7B Gene

    167 amino acids
    Molecular mass:
    18335 Da
    Quaternary structure:
    No Data Available
    • Shares an exon with the neighboring tail-to-tail oriented gene CRTAC1.

neXtProt entry for GOLGA7B Gene

Post-translational modifications for GOLGA7B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA7B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA7B Gene

Domains & Families for GOLGA7B Gene

Gene Families for GOLGA7B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA7B Gene


Suggested Antigen Peptide Sequences for GOLGA7B Gene

GenScript: Design optimal peptide antigens:
  • Golgin subfamily A member 7B (GOG7B_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ERF4 family.
  • Belongs to the ERF4 family.
genes like me logo Genes that share domains with GOLGA7B: view

Function for GOLGA7B Gene

Molecular function for GOLGA7B Gene

UniProtKB/Swiss-Prot Function:
May be involved in protein transport from Golgi to cell surface.

Phenotypes From GWAS Catalog for GOLGA7B Gene

Gene Ontology (GO) - Molecular Function for GOLGA7B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0019706 contributes_to protein-cysteine S-palmitoyltransferase activity IBA 21873635
GO:0019899 enzyme binding IPI 31402609
genes like me logo Genes that share ontologies with GOLGA7B: view
genes like me logo Genes that share phenotypes with GOLGA7B: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA7B

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GOLGA7B Gene

Localization for GOLGA7B Gene

Subcellular locations from UniProtKB/Swiss-Prot for GOLGA7B Gene

Golgi apparatus membrane. Lipid-anchor.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA7B gene
Compartment Confidence
golgi apparatus 3
cytosol 2
nucleus 1
extracellular 0
endoplasmic reticulum 0
lysosome 0

Gene Ontology (GO) - Cellular Components for GOLGA7B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0002178 palmitoyltransferase complex IBA 21873635
GO:0005794 Golgi apparatus IEA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with GOLGA7B: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for GOLGA7B Gene

Pathways & Interactions for GOLGA7B Gene

PathCards logo

SuperPathways for GOLGA7B Gene

No Data Available

Gene Ontology (GO) - Biological Process for GOLGA7B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006612 protein targeting to membrane IBA 21873635
GO:0018230 peptidyl-L-cysteine S-palmitoylation IBA 21873635
genes like me logo Genes that share ontologies with GOLGA7B: view

No data available for Pathways by source and SIGNOR curated interactions for GOLGA7B Gene

Drugs & Compounds for GOLGA7B Gene

No Compound Related Data Available

Transcripts for GOLGA7B Gene

mRNA/cDNA for GOLGA7B Gene

10 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA7B

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA7B Gene

No ASD Table

Relevant External Links for GOLGA7B Gene

GeneLoc Exon Structure for

Expression for GOLGA7B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GOLGA7B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for GOLGA7B Gene

This gene is overexpressed in Brain - Cerebellum (x7.8), Brain - Cerebellar Hemisphere (x6.9), and Brain - Cortex (x4.5).

Protein differential expression in normal tissues from HIPED for GOLGA7B Gene

This gene is overexpressed in Pancreatic juice (25.4), Tlymphocyte (19.8), Frontal cortex (10.0), and Lung (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GOLGA7B Gene

Protein tissue co-expression partners for GOLGA7B Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GOLGA7B

SOURCE GeneReport for Unigene cluster for GOLGA7B Gene:


mRNA Expression by UniProt/SwissProt for GOLGA7B Gene:

Tissue specificity: Expressed in brain, but not in lung, nor chondrocytes.

Evidence on tissue expression from TISSUES for GOLGA7B Gene

  • Nervous system(4.4)
genes like me logo Genes that share expression patterns with GOLGA7B: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA7B Gene

Orthologs for GOLGA7B Gene

This gene was present in the common ancestor of animals.

Orthologs for GOLGA7B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia GOLGA7B 30 31
  • 99.4 (n)
(Monodelphis domestica)
Mammalia GOLGA7B 31
  • 96 (a)
(Canis familiaris)
Mammalia GOLGA7B 30 31
  • 94.56 (n)
(Bos Taurus)
Mammalia GOLGA7B 30 31
  • 94.41 (n)
(Mus musculus)
Mammalia Golga7b 30 17 31
  • 91.22 (n)
(Rattus norvegicus)
Mammalia Golga7b 30
  • 91.22 (n)
(Gallus gallus)
Aves GOLGA7B 31
  • 89 (a)
LOC423837 30
  • 84.63 (n)
(Anolis carolinensis)
Reptilia GOLGA7B 31
  • 90 (a)
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia golga7b 30
  • 79.67 (n)
(Danio rerio)
Actinopterygii golga7bb 30 31
  • 79.38 (n)
golga7ba 31
  • 72 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004120 30
  • 64.96 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta CG5447 30 31
  • 60.56 (n)
(Caenorhabditis elegans)
Secernentea Y57G11C.33 31
  • 24 (a)
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.5432 31
  • 32 (a)
Species where no ortholog for GOLGA7B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for GOLGA7B Gene

Gene Tree for GOLGA7B (if available)
Gene Tree for GOLGA7B (if available)
Evolutionary constrained regions (ECRs) for GOLGA7B: view image

Paralogs for GOLGA7B Gene

Paralogs for GOLGA7B Gene

(1) SIMAP similar genes for GOLGA7B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with GOLGA7B: view

Variants for GOLGA7B Gene

Additional dbSNP identifiers (rs#s) for GOLGA7B Gene

Structural Variations from Database of Genomic Variants (DGV) for GOLGA7B Gene

Variant ID Type Subtype PubMed ID
nsv1045435 CNV gain 25217958
nsv1047572 CNV gain 25217958
nsv1069508 CNV deletion 25765185
nsv1112594 CNV deletion 24896259
nsv819567 CNV gain 19587683
nsv951000 CNV deletion 24416366

Variation tolerance for GOLGA7B Gene

Residual Variation Intolerance Score: 36.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.73; 78.79% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA7B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GOLGA7B Gene

Disorders for GOLGA7B Gene

No disorders were found for GOLGA7B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA7B Gene

Publications for GOLGA7B Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate cell adhesion. (PMID: 31402609) Woodley KT … Collins MO (EMBO reports 2019) 3
  5. A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway. (PMID: 30561431) Van Quickelberghe E … Gevaert K (Scientific data 2018) 3

Products for GOLGA7B Gene

Sources for GOLGA7B Gene