Aliases for GOLGA6L6 Gene

Aliases for GOLGA6L6 Gene

  • Golgin A6 Family Like 6 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 6-Like 6 2 3
  • Golgin Subfamily A Member 6-Like Protein 6 3 4
  • Putative Golgin Subfamily A Member 6-Like Protein 6 3

External Ids for GOLGA6L6 Gene

Previous GeneCards Identifiers for GOLGA6L6 Gene

  • GC15M019005
  • GC15M020737

Summaries for GOLGA6L6 Gene

GeneCards Summary for GOLGA6L6 Gene

GOLGA6L6 (Golgin A6 Family Like 6) is a Protein Coding gene. An important paralog of this gene is GOLGA6L22.

Additional gene information for GOLGA6L6 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GOLGA6L6 Gene

Genomics for GOLGA6L6 Gene

Genomic Locations for GOLGA6L6 Gene

Genomic Locations for GOLGA6L6 Gene
chr15:20,531,856-20,541,800
(GRCh38/hg38)
Size:
9,945 bases
Orientation:
Minus strand
chr15:20,737,094-20,747,114
(GRCh37/hg19)
Size:
10,021 bases
Orientation:
Minus strand

Genomic View for GOLGA6L6 Gene

Genes around GOLGA6L6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA6L6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA6L6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA6L6 Gene

No data available for GeneHancer (GH) Regulatory Elements for GOLGA6L6 Gene

Proteins for GOLGA6L6 Gene

  • Protein details for GOLGA6L6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MZA4-GG6L6_HUMAN
    Recommended name:
    Golgin subfamily A member 6-like protein 6
    Protein Accession:
    A8MZA4
    Secondary Accessions:
    • D3YTC0

    Protein attributes for GOLGA6L6 Gene

    Size:
    724 amino acids
    Molecular mass:
    90952 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA6L6 Gene

Post-translational modifications for GOLGA6L6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA6L6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA6L6 Gene

Domains & Families for GOLGA6L6 Gene

Gene Families for GOLGA6L6 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA6L6 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GOLGA6L6 Gene

GenScript: Design optimal peptide antigens:
  • Putative golgin subfamily A member 6-like protein 6 (GG6L6_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A8MZA4

UniProtKB/Swiss-Prot:

GG6L6_HUMAN :
  • Belongs to the GOLGA6 family.
Family:
  • Belongs to the GOLGA6 family.
genes like me logo Genes that share domains with GOLGA6L6: view

Function for GOLGA6L6 Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA6L6 Gene

Localization for GOLGA6L6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GOLGA6L6 Gene

Pathways & Interactions for GOLGA6L6 Gene

PathCards logo

SuperPathways for GOLGA6L6 Gene

No Data Available

Interacting Proteins for GOLGA6L6 Gene

;

Gene Ontology (GO) - Biological Process for GOLGA6L6 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GOLGA6L6 Gene

Drugs & Compounds for GOLGA6L6 Gene

No Compound Related Data Available

Transcripts for GOLGA6L6 Gene

mRNA/cDNA for GOLGA6L6 Gene

1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA6L6 Gene

No ASD Table

Relevant External Links for GOLGA6L6 Gene

GeneLoc Exon Structure for
GOLGA6L6

Expression for GOLGA6L6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GOLGA6L6 Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA6L6 Gene

This gene is overexpressed in Testis (x51.9).

Protein differential expression in normal tissues from HIPED for GOLGA6L6 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GOLGA6L6 Gene



Protein tissue co-expression partners for GOLGA6L6 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GOLGA6L6

SOURCE GeneReport for Unigene cluster for GOLGA6L6 Gene:

Hs.125917
genes like me logo Genes that share expression patterns with GOLGA6L6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA6L6 Gene

Orthologs for GOLGA6L6 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for GOLGA6L6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GOLGA6L1 30
  • 95.84 (n)
Species where no ortholog for GOLGA6L6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for GOLGA6L6 Gene

ENSEMBL:
Gene Tree for GOLGA6L6 (if available)
TreeFam:
Gene Tree for GOLGA6L6 (if available)

Paralogs for GOLGA6L6 Gene

(6) SIMAP similar genes for GOLGA6L6 Gene using alignment to 1 proteins:

  • GG6L6_HUMAN
genes like me logo Genes that share paralogs with GOLGA6L6: view

Variants for GOLGA6L6 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GOLGA6L6 Gene

SNP ID Clinical significance and condition Chr 15 pos Variation AA Info Type
rs28590435 Benign: not specified 20,534,587(-) G/A MISSENSE_VARIANT
rs4932675 Not Provided: not provided 20,534,419(-) A/G MISSENSE_VARIANT
rs4932676 Not Provided: not provided 20,534,396(-) A/C MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for GOLGA6L6 Gene

Structural Variations from Database of Genomic Variants (DGV) for GOLGA6L6 Gene

Variant ID Type Subtype PubMed ID
dgv1n1 OTHER inversion 15895083
dgv2174n100 CNV gain 25217958
dgv2175n100 CNV gain 25217958
dgv2179n100 CNV gain 25217958
dgv2181n100 CNV gain 25217958
dgv2182n100 CNV gain 25217958
dgv2183n100 CNV loss 25217958
dgv2186n100 CNV gain+loss 25217958
dgv2187n100 CNV gain 25217958
dgv2188n100 CNV loss 25217958
dgv2189n100 CNV gain+loss 25217958
dgv2190n100 CNV gain+loss 25217958
dgv2191n100 CNV gain+loss 25217958
dgv2192n100 CNV loss 25217958
dgv2193n100 CNV gain+loss 25217958
dgv2194n100 CNV loss 25217958
dgv2195n100 CNV loss 25217958
dgv2200n100 CNV gain 25217958
dgv2201n100 CNV gain 25217958
dgv2202n100 CNV loss 25217958
dgv2206n100 CNV gain 25217958
dgv2207n100 CNV loss 25217958
dgv2208n100 CNV gain 25217958
dgv2209n100 CNV gain+loss 25217958
dgv2210n100 CNV gain 25217958
dgv2211n100 CNV loss 25217958
dgv2212n100 CNV gain 25217958
dgv2213n100 CNV loss 25217958
dgv2214n100 CNV gain 25217958
dgv2215n100 CNV loss 25217958
dgv2217n100 CNV gain 25217958
dgv2221n100 CNV gain+loss 25217958
dgv2222n100 CNV gain+loss 25217958
dgv2228n100 CNV gain 25217958
dgv2231n100 CNV gain+loss 25217958
dgv2232n100 CNV loss 25217958
dgv2233n100 CNV loss 25217958
dgv2236n100 CNV gain 25217958
dgv2237n100 CNV gain 25217958
dgv2238n100 CNV gain 25217958
dgv2243n100 CNV gain+loss 25217958
dgv2244n100 CNV loss 25217958
dgv2245n100 CNV loss 25217958
dgv2246n100 CNV gain+loss 25217958
dgv2249n100 CNV gain+loss 25217958
dgv2250n100 CNV gain+loss 25217958
dgv2255n100 CNV gain 25217958
dgv2256n100 CNV loss 25217958
dgv2257n100 CNV gain 25217958
dgv2266n100 CNV loss 25217958
dgv2278n100 CNV gain 25217958
dgv2279n100 CNV loss 25217958
dgv2280n100 CNV loss 25217958
dgv2281n100 CNV gain+loss 25217958
dgv2282n100 CNV gain 25217958
dgv2283n100 CNV gain 25217958
dgv2284n100 CNV gain 25217958
dgv28n68 CNV gain+loss 17160897
dgv4162n54 CNV loss 21841781
dgv4164n54 CNV loss 21841781
dgv4166n54 CNV gain 21841781
dgv4174n54 CNV loss 21841781
dgv4180n54 CNV gain 21841781
dgv4182n54 CNV loss 21841781
dgv4183n54 CNV loss 21841781
dgv4194n54 CNV loss 21841781
dgv4203n54 CNV loss 21841781
dgv43n16 CNV insertion 17901297
dgv91e55 CNV gain 17911159
dgv92e55 CNV gain 17911159
dgv93e55 CNV gain 17911159
dgv95e55 CNV loss 17911159
dgv96e55 CNV loss 17911159
esv1004259 OTHER inversion 20482838
esv21579 CNV gain+loss 19812545
esv2751488 CNV loss 17911159
esv29956 CNV loss 18421352
esv33051 CNV gain+loss 17666407
esv3432056 CNV duplication 20981092
esv3584810 CNV gain 24956385
esv3584832 CNV gain 24956385
esv3892607 CNV gain 25118596
esv988919 CNV loss 20482838
nsv1035597 CNV gain 25217958
nsv1078369 CNV duplication 25765185
nsv1110245 CNV duplication 24896259
nsv1160218 CNV duplication 26073780
nsv1452 CNV deletion 18451855
nsv428296 CNV gain+loss 18775914
nsv433426 CNV gain 18776910
nsv436198 CNV deletion 17901297
nsv482173 CNV gain 20164927
nsv511040 OTHER inversion 20534489
nsv567312 CNV gain 21841781
nsv7260 OTHER inversion 18451855
nsv819770 CNV gain 19587683
nsv821678 CNV loss 15273396
nsv832908 CNV gain 17160897
nsv9179 CNV gain+loss 18304495
nsv952313 CNV deletion 24416366
nsv977648 CNV duplication 23825009

Variation tolerance for GOLGA6L6 Gene

Gene Damage Index Score: 6.98; 79.94% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA6L6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA6L6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA6L6 Gene

Disorders for GOLGA6L6 Gene

Additional Disease Information for GOLGA6L6

No disorders were found for GOLGA6L6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA6L6 Gene

Publications for GOLGA6L6 Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 54

Products for GOLGA6L6 Gene

Sources for GOLGA6L6 Gene