Aliases for GOLGA6L10 Gene

Aliases for GOLGA6L10 Gene

  • Golgin A6 Family Like 10 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 6-Like 10 2 3
  • Golgin Subfamily A Member 6-Like Protein 10 3 4
  • Golgin A6 Family-Like 18 2 3
  • GOLGA6L18 3 4
  • Putative Golgin Subfamily A Member 6-Like Protein 10 3
  • GOLGA6L10 5

External Ids for GOLGA6L10 Gene

Previous HGNC Symbols for GOLGA6L10 Gene

  • GOLGA6L18

Previous GeneCards Identifiers for GOLGA6L10 Gene

  • GC15M080420
  • GC15M082635

Summaries for GOLGA6L10 Gene

GeneCards Summary for GOLGA6L10 Gene

GOLGA6L10 (Golgin A6 Family Like 10) is a Protein Coding gene. Diseases associated with GOLGA6L10 include Pancreatic Adenosquamous Carcinoma. An important paralog of this gene is GOLGA6L4.

Additional gene information for GOLGA6L10 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GOLGA6L10 Gene

Genomics for GOLGA6L10 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for GOLGA6L10 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA6L10 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GOLGA6L10

Genomic Locations for GOLGA6L10 Gene

Genomic Locations for GOLGA6L10 Gene
chr15:82,339,993-82,349,475
(GRCh38/hg38)
Size:
9,483 bases
Orientation:
Minus strand
chr15:82,633,122-82,641,706
(GRCh37/hg19)
Size:
8,585 bases
Orientation:
Minus strand

Genomic View for GOLGA6L10 Gene

Genes around GOLGA6L10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA6L10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA6L10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA6L10 Gene

Proteins for GOLGA6L10 Gene

  • Protein details for GOLGA6L10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NI86-GG6LA_HUMAN
    Recommended name:
    Golgin subfamily A member 6-like protein 10
    Protein Accession:
    A6NI86
    Secondary Accessions:
    • A0A087WVD5
    • D6RB28

    Protein attributes for GOLGA6L10 Gene

    Size:
    522 amino acids
    Molecular mass:
    60902 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA6L10 Gene

Post-translational modifications for GOLGA6L10 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA6L10 Gene

No data available for DME Specific Peptides for GOLGA6L10 Gene

Domains & Families for GOLGA6L10 Gene

Gene Families for GOLGA6L10 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA6L10 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GOLGA6L10 Gene

GenScript: Design optimal peptide antigens:
  • Putative golgin subfamily A member 6-like protein 10 (GG6LA_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A6NI86

UniProtKB/Swiss-Prot:

GG6LA_HUMAN :
  • Belongs to the GOLGA6 family.
Family:
  • Belongs to the GOLGA6 family.
genes like me logo Genes that share domains with GOLGA6L10: view

Function for GOLGA6L10 Gene

Phenotypes From GWAS Catalog for GOLGA6L10 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA6L10

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GOLGA6L10 Gene

Localization for GOLGA6L10 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA6L10 gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for GOLGA6L10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005794 Golgi apparatus IEA --
genes like me logo Genes that share ontologies with GOLGA6L10: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA6L10 Gene

Pathways & Interactions for GOLGA6L10 Gene

PathCards logo

SuperPathways for GOLGA6L10 Gene

No Data Available

Interacting Proteins for GOLGA6L10 Gene

Gene Ontology (GO) - Biological Process for GOLGA6L10 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GOLGA6L10 Gene

Drugs & Compounds for GOLGA6L10 Gene

No Compound Related Data Available

Transcripts for GOLGA6L10 Gene

mRNA/cDNA for GOLGA6L10 Gene

2 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA6L10

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA6L10 Gene

No ASD Table

Relevant External Links for GOLGA6L10 Gene

GeneLoc Exon Structure for
GOLGA6L10

Expression for GOLGA6L10 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GOLGA6L10 Gene

mRNA expression in normal human tissues for GOLGA6L10 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for GOLGA6L10 Gene

This gene is overexpressed in Testis (x5.8).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GOLGA6L10

SOURCE GeneReport for Unigene cluster for GOLGA6L10 Gene:

Hs.459120
genes like me logo Genes that share expression patterns with GOLGA6L10: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA6L10 Gene

Orthologs for GOLGA6L10 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for GOLGA6L10 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia LOC744787 30
  • 94.3 (n)
Species where no ortholog for GOLGA6L10 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for GOLGA6L10 Gene

ENSEMBL:
Gene Tree for GOLGA6L10 (if available)
TreeFam:
Gene Tree for GOLGA6L10 (if available)

Paralogs for GOLGA6L10 Gene

(19) SIMAP similar genes for GOLGA6L10 Gene using alignment to 1 proteins:

  • GG6LA_HUMAN
genes like me logo Genes that share paralogs with GOLGA6L10: view

Variants for GOLGA6L10 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GOLGA6L10 Gene

SNP ID Clinical significance and condition Chr 15 pos Variation AA Info Type
rs200685620 Benign: not specified 82,344,779(-) C/T MISSENSE_VARIANT
rs201670904 Benign: not specified 82,344,706(-) C/T MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for GOLGA6L10 Gene

Structural Variations from Database of Genomic Variants (DGV) for GOLGA6L10 Gene

Variant ID Type Subtype PubMed ID
esv24498 CNV gain+loss 19812545
nsv1069871 CNV deletion 25765185
nsv1120052 OTHER inversion 24896259

Variation tolerance for GOLGA6L10 Gene

Gene Damage Index Score: 5.39; 71.11% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA6L10 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA6L10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA6L10 Gene

Disorders for GOLGA6L10 Gene

MalaCards: The human disease database

(1) MalaCards diseases for GOLGA6L10 Gene - From: DISEASES

Disorder Aliases PubMed IDs
pancreatic adenosquamous carcinoma
  • adenosquamous carcinoma of pancreas
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for GOLGA6L10

genes like me logo Genes that share disorders with GOLGA6L10: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GOLGA6L10 Gene

Publications for GOLGA6L10 Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4
  2. Non-erythroid beta spectrin interacting proteins and their effects on spectrin tetramerization. (PMID: 21866423) Sevinc A … Fung LW (Cellular & molecular biology letters 2011) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  4. Toward a complete human genome sequence. (PMID: 9847074) Sanger Center … Genome Sequencing Center (Genome research 1998) 3

Products for GOLGA6L10 Gene

Sources for GOLGA6L10 Gene