Aliases for GOLGA6L1 Gene

Aliases for GOLGA6L1 Gene

  • Golgin A6 Family Like 1 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 6-Like 1 2 3
  • Golgin Subfamily A Member 6-Like Protein 1 3 4
  • GOLGA6L1 5

External Ids for GOLGA6L1 Gene

Previous GeneCards Identifiers for GOLGA6L1 Gene

  • GC15P020297
  • GC15P022736
  • GC15P001041
  • GC15Mi00227

Summaries for GOLGA6L1 Gene

GeneCards Summary for GOLGA6L1 Gene

GOLGA6L1 (Golgin A6 Family Like 1) is a Protein Coding gene. An important paralog of this gene is GOLGA6L6.

Additional gene information for GOLGA6L1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GOLGA6L1 Gene

Genomics for GOLGA6L1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for GOLGA6L1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J023179 Promoter 0.5 Ensembl 0.3 -43.1 -43079 1 PRDM10 EZH2 ABCB10P1 ENSG00000278541 GOLGA6L1 LOC102723623
GH15J023079 Enhancer 0.3 Ensembl 0.2 +56.2 56222 2 CTCF CYFIP1 ELMO2P1 piR-34837-002 TUBGCP5 RF00017-1706 GOLGA6L1
GH15J023225 Promoter 0.3 Ensembl 0.2 -89.4 -89378 0.8 ENSG00000278552 LOC100421667 lnc-GOLGA6L1-2 piR-31534-195 GOLGA6L1 LOC102723623
GH15J023057 Enhancer 0.2 Ensembl 0.2 +79.2 79221 0.4 piR-34837-002 TUBGCP5 ELMO2P1 RF00017-1706 GOLGA6L1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA6L1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GOLGA6L1

Genomic Locations for GOLGA6L1 Gene

Genomic Locations for GOLGA6L1 Gene
chr15:23,127,066-23,136,822
(GRCh38/hg38)
Size:
9,757 bases
Orientation:
Minus strand
chr15:22,736,246-22,746,002
(GRCh37/hg19)
Size:
9,757 bases
Orientation:
Plus strand

Genomic View for GOLGA6L1 Gene

Genes around GOLGA6L1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA6L1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA6L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA6L1 Gene

Proteins for GOLGA6L1 Gene

  • Protein details for GOLGA6L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7Z2-GG6L1_HUMAN
    Recommended name:
    Golgin subfamily A member 6-like protein 1
    Protein Accession:
    Q8N7Z2
    Secondary Accessions:
    • A0A087WU96

    Protein attributes for GOLGA6L1 Gene

    Size:
    668 amino acids
    Molecular mass:
    83069 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA6L1 Gene

Post-translational modifications for GOLGA6L1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA6L1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA6L1 Gene

Domains & Families for GOLGA6L1 Gene

Gene Families for GOLGA6L1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA6L1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GOLGA6L1 Gene

GenScript: Design optimal peptide antigens:
  • LOC283767 protein (A1L183_HUMAN)
  • Golgin subfamily A member 6-like protein 1 (GG6L1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8N7Z2

UniProtKB/Swiss-Prot:

GG6L1_HUMAN :
  • Belongs to the GOLGA6 family.
Family:
  • Belongs to the GOLGA6 family.
genes like me logo Genes that share domains with GOLGA6L1: view

Function for GOLGA6L1 Gene

Phenotypes for GOLGA6L1 Gene

GenomeRNAi human phenotypes for GOLGA6L1:
genes like me logo Genes that share phenotypes with GOLGA6L1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA6L1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA6L1 Gene

Localization for GOLGA6L1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA6L1 gene
Compartment Confidence
nucleus 2
cytosol 1
mitochondrion 0

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GOLGA6L1 Gene

Pathways & Interactions for GOLGA6L1 Gene

PathCards logo

SuperPathways for GOLGA6L1 Gene

No Data Available

Interacting Proteins for GOLGA6L1 Gene

Gene Ontology (GO) - Biological Process for GOLGA6L1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GOLGA6L1 Gene

Drugs & Compounds for GOLGA6L1 Gene

No Compound Related Data Available

Transcripts for GOLGA6L1 Gene

mRNA/cDNA for GOLGA6L1 Gene

1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA6L1

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA6L1 Gene

No ASD Table

Relevant External Links for GOLGA6L1 Gene

GeneLoc Exon Structure for
GOLGA6L1

Expression for GOLGA6L1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GOLGA6L1 Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA6L1 Gene

This gene is overexpressed in Testis (x48.6).

Protein differential expression in normal tissues from HIPED for GOLGA6L1 Gene

This gene is overexpressed in Heart (56.2) and Adipocyte (12.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GOLGA6L1 Gene



Protein tissue co-expression partners for GOLGA6L1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GOLGA6L1

SOURCE GeneReport for Unigene cluster for GOLGA6L1 Gene:

Hs.531569
genes like me logo Genes that share expression patterns with GOLGA6L1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA6L1 Gene

Orthologs for GOLGA6L1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for GOLGA6L1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia GOLGA6L1 30
  • 96.77 (n)
Species where no ortholog for GOLGA6L1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for GOLGA6L1 Gene

ENSEMBL:
Gene Tree for GOLGA6L1 (if available)
TreeFam:
Gene Tree for GOLGA6L1 (if available)

Paralogs for GOLGA6L1 Gene

(10) SIMAP similar genes for GOLGA6L1 Gene using alignment to 3 proteins:

  • GG6L1_HUMAN
  • H0YK22_HUMAN
  • I3L087_HUMAN
genes like me logo Genes that share paralogs with GOLGA6L1: view

Variants for GOLGA6L1 Gene

Additional dbSNP identifiers (rs#s) for GOLGA6L1 Gene

Structural Variations from Database of Genomic Variants (DGV) for GOLGA6L1 Gene

Variant ID Type Subtype PubMed ID
dgv2403n100 CNV gain 25217958
dgv2404n100 CNV gain 25217958
dgv2405n100 CNV gain+loss 25217958
dgv2406n100 CNV gain 25217958
dgv2407n100 CNV gain+loss 25217958
dgv2408n100 CNV loss 25217958
esv2474417 CNV loss 19546169
esv3892626 CNV gain+loss 25118596
nsv1036020 CNV loss 25217958
nsv433429 CNV gain 18776910
nsv442359 CNV gain+loss 18776908
nsv511042 OTHER inversion 20534489
nsv952568 CNV deletion 24416366
nsv976888 CNV duplication 23825009

Variation tolerance for GOLGA6L1 Gene

Gene Damage Index Score: 0.14; 3.14% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA6L1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA6L1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GOLGA6L1 Gene

Disorders for GOLGA6L1 Gene

No disorders were found for GOLGA6L1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA6L1 Gene

Publications for GOLGA6L1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for GOLGA6L1 Gene

Sources for GOLGA6L1 Gene