Aliases for GOLGA6D Gene

Aliases for GOLGA6D Gene

  • Golgin A6 Family Member D 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 6D 2 3
  • Golgin Subfamily A Member 6D 3 4
  • Putative Golgin Subfamily A Member 6D 3
  • Golgin A6 Family, Member D 2
  • GOLGA6D 5

External Ids for GOLGA6D Gene

Previous GeneCards Identifiers for GOLGA6D Gene

  • GC15P073363
  • GC15P075577
  • GC15P052343
  • GC15P075259

Summaries for GOLGA6D Gene

GeneCards Summary for GOLGA6D Gene

GOLGA6D (Golgin A6 Family Member D) is a Protein Coding gene. An important paralog of this gene is GOLGA6C.

Additional gene information for GOLGA6D Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GOLGA6D Gene

Genomics for GOLGA6D Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for GOLGA6D Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J075282 Promoter 0.7 EPDnew Ensembl 600.7 +0.1 58 0.2 GOLGA6D piR-45301-005 piR-40058-004 piR-51363-020 COMMD4
GH15J075284 Enhancer 0.2 Ensembl 600.7 +1.6 1565 0.4 GOLGA6D piR-51363-020 COMMD4
GH15J075280 Enhancer 0.2 Ensembl 600.7 -1.8 -1834 0.4 GOLGA6D piR-45301-005 piR-40058-004 piR-55310-003 GOLGA6C
GH15J075283 Enhancer 0.2 Ensembl 600.7 +0.9 866 0.2 GOLGA6D piR-45301-005 piR-51363-020 COMMD4
GH15J075307 Enhancer 0.9 Ensembl ENCODE 0.3 +25.4 25366 0.8 CTCF PRDM10 TARDBP MTA1 REST RAD21 ZNF600 ZBTB20 ZNF444 RCOR1 MIR631 DNM1P34 ANP32BP1 GOLGA6D COMMD4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GOLGA6D on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GOLGA6D

Top Transcription factor binding sites by QIAGEN in the GOLGA6D gene promoter:
  • Nkx2-5
  • Oct-B1
  • oct-B2
  • oct-B3
  • POU2F1
  • POU2F1a
  • POU2F2
  • POU2F2 (Oct-2.1)
  • POU2F2B
  • POU2F2C

Genomic Locations for GOLGA6D Gene

Genomic Locations for GOLGA6D Gene
chr15:75,282,835-75,295,807
(GRCh38/hg38)
Size:
12,973 bases
Orientation:
Plus strand
chr15:75,575,176-75,588,148
(GRCh37/hg19)
Size:
12,973 bases
Orientation:
Plus strand

Genomic View for GOLGA6D Gene

Genes around GOLGA6D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA6D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA6D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA6D Gene

Proteins for GOLGA6D Gene

  • Protein details for GOLGA6D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CG33-GOG6D_HUMAN
    Recommended name:
    Golgin subfamily A member 6D
    Protein Accession:
    P0CG33

    Protein attributes for GOLGA6D Gene

    Size:
    693 amino acids
    Molecular mass:
    79896 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA6D Gene

Post-translational modifications for GOLGA6D Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA6D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA6D Gene

Domains & Families for GOLGA6D Gene

Gene Families for GOLGA6D Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GOLGA6D Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GOLGA6D Gene

GenScript: Design optimal peptide antigens:
  • Putative golgin subfamily A member 6D (GOG6D_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P0CG33

UniProtKB/Swiss-Prot:

GOG6D_HUMAN :
  • Belongs to the GOLGA6 family.
Family:
  • Belongs to the GOLGA6 family.
genes like me logo Genes that share domains with GOLGA6D: view

Function for GOLGA6D Gene

Phenotypes From GWAS Catalog for GOLGA6D Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA6D

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA6D Gene

Localization for GOLGA6D Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA6D gene
Compartment Confidence
golgi apparatus 3
nucleus 2
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for GOLGA6D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000137 Golgi cis cisterna IBA 21873635
GO:0005794 Golgi apparatus IEA,IBA 21873635
GO:0005801 cis-Golgi network IBA 21873635
GO:0032580 Golgi cisterna membrane IBA 21873635
genes like me logo Genes that share ontologies with GOLGA6D: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for GOLGA6D Gene

Pathways & Interactions for GOLGA6D Gene

PathCards logo

SuperPathways for GOLGA6D Gene

No Data Available

Interacting Proteins for GOLGA6D Gene

Gene Ontology (GO) - Biological Process for GOLGA6D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007030 Golgi organization IBA 21873635
GO:0051225 NOT spindle assembly IBA 21873635
genes like me logo Genes that share ontologies with GOLGA6D: view

No data available for Pathways by source and SIGNOR curated interactions for GOLGA6D Gene

Drugs & Compounds for GOLGA6D Gene

No Compound Related Data Available

Transcripts for GOLGA6D Gene

mRNA/cDNA for GOLGA6D Gene

1 REFSEQ mRNAs :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GOLGA6D

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA6D Gene

No ASD Table

Relevant External Links for GOLGA6D Gene

GeneLoc Exon Structure for
GOLGA6D

Expression for GOLGA6D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GOLGA6D Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA6D Gene

This gene is overexpressed in Testis (x46.8).
genes like me logo Genes that share expression patterns with GOLGA6D: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA6D Gene

Orthologs for GOLGA6D Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA6D Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 94 (a)
ManyToMany
-- 31
  • 93 (a)
ManyToMany
-- 31
  • 92 (a)
ManyToMany
Cow
(Bos Taurus)
Mammalia -- 31
  • 33 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 33 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Golga2 31
  • 32 (a)
OneToMany
Dog
(Canis familiaris)
Mammalia -- 31
  • 31 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 30 (a)
OneToMany
Chicken
(Gallus gallus)
Aves -- 31
  • 27 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 26 (a)
OneToMany
Zebrafish
(Danio rerio)
Actinopterygii golga2 31
  • 21 (a)
OneToMany
Species where no ortholog for GOLGA6D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for GOLGA6D Gene

ENSEMBL:
Gene Tree for GOLGA6D (if available)
TreeFam:
Gene Tree for GOLGA6D (if available)

Paralogs for GOLGA6D Gene

Pseudogenes.org Pseudogenes for GOLGA6D Gene

genes like me logo Genes that share paralogs with GOLGA6D: view

Variants for GOLGA6D Gene

Additional dbSNP identifiers (rs#s) for GOLGA6D Gene

Structural Variations from Database of Genomic Variants (DGV) for GOLGA6D Gene

Variant ID Type Subtype PubMed ID
dgv1242n106 CNV duplication 24896259
dgv2621n100 CNV gain 25217958
esv22004 CNV gain 19812545
esv3334067 CNV duplication 20981092
esv3364343 CNV duplication 20981092
esv3416661 CNV duplication 20981092
esv996044 CNV gain 20482838
nsv1151179 CNV duplication 26484159
nsv1613 CNV deletion 18451855
nsv498851 CNV loss 21111241
nsv821359 CNV duplication 20802225
nsv833056 CNV gain 17160897
nsv9277 CNV loss 18304495
nsv977736 CNV duplication 23825009

Variation tolerance for GOLGA6D Gene

Gene Damage Index Score: 3.52; 55.56% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GOLGA6D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA6D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GOLGA6D Gene

Disorders for GOLGA6D Gene

Additional Disease Information for GOLGA6D

No disorders were found for GOLGA6D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA6D Gene

Publications for GOLGA6D Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for GOLGA6D Gene

Sources for GOLGA6D Gene