Aliases for GOLGA4 Gene
External Ids for GOLGA4 Gene
Previous GeneCards Identifiers for GOLGA4 Gene
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
GeneCards Summary for GOLGA4 Gene
GOLGA4 (Golgin A4) is a Protein Coding gene. Diseases associated with GOLGA4 include Chronic Neutrophilic Leukemia and Alzheimer Disease 14. Among its related pathways are Vesicle-mediated transport and Golgi-to-ER retrograde transport. Gene Ontology (GO) annotations related to this gene include nucleotide binding and GTPase binding.
UniProtKB/Swiss-Prot Summary for GOLGA4 Gene
Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Involved in endosome-to-Golgi trafficking (PubMed:29084197).