Aliases for GNLY Gene
External Ids for GNLY Gene
Previous HGNC Symbols for GNLY Gene
Previous GeneCards Identifiers for GNLY Gene
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for GNLY Gene
GNLY (Granulysin) is a Protein Coding gene. Diseases associated with GNLY include Erythema Multiforme and Kyphoscoliotic Heart Disease. Among its related pathways are Allograft rejection and Defensins.
UniProtKB/Swiss-Prot Summary for GNLY Gene
Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.