Aliases for GNL2 Gene
External Ids for GNL2 Gene
Previous GeneCards Identifiers for GNL2 Gene
GeneCards Summary for GNL2 Gene
GNL2 (G Protein Nucleolar 2) is a Protein Coding gene. Diseases associated with GNL2 include Robinow Syndrome, Autosomal Dominant 1 and Siberian Tick Typhus. Among its related pathways are Ribosome biogenesis in eukaryotes. Gene Ontology (GO) annotations related to this gene include GTPase activity. An important paralog of this gene is GNL3L.
UniProtKB/Swiss-Prot Summary for GNL2 Gene
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195).