Aliases for GNG4 Gene
Aliases for GNG4 Gene
External Ids for GNG4 Gene
- HGNC: 4407
- Entrez Gene: 2786
- Ensembl: ENSG00000168243
- OMIM: 604388
- UniProtKB: P50150
Previous GeneCards Identifiers for GNG4 Gene
- GC01M233846
- GC01M231167
- GC01M232010
- GC01M232755
- GC01M232040
- GC01M235710
- GC01M206162
Summaries for GNG4 Gene
GeneCards Summary for GNG4 Gene
GNG4 (G Protein Subunit Gamma 4) is a Protein Coding gene. Among its related pathways are Akt Signaling and Presynaptic function of Kainate receptors. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity. An important paralog of this gene is GNG2.
UniProtKB/Swiss-Prot for GNG4 Gene
-
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
-
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand binding causes a receptor conformational change, detaching the G protein and switching it 'on'.
No data available for Entrez Gene Summary , CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GNG4 Gene
Genomics for GNG4 Gene
GeneHancer (GH) Regulatory Elements for GNG4 Gene
Promoters and enhancers for GNG4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around GNG4 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the GNG4 gene promoter:
-
- FOXF2
- HNF-3beta
- RSRFC4
- IRF-2
- AML1a
Regulatory Element Products
Genomic Locations for GNG4 Gene
Genomic Locations for GNG4 Gene
- chr1:235,547,685-235,650,754
- (GRCh38/hg38)
- Size:
- 103,070 bases
- Orientation:
- Minus strand
- chr1:235,710,985-235,814,054
- (GRCh37/hg19)
- Size:
- 103,070 bases
- Orientation:
- Minus strand
Genomic View for GNG4 Gene
Genes around GNG4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q42.3 by Entrez Gene
- 1q42.3 by HGNC
- 1q42.3 by Ensembl
GNG4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GNG4 Gene
Proteins for GNG4 Gene
-
Protein details for GNG4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P50150-GBG4_HUMAN
- Recommended name:
- Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
- Protein Accession:
- P50150
Protein attributes for GNG4 Gene
- Size:
- 75 amino acids
- Molecular mass:
- 8389 Da
- Quaternary structure:
-
- G proteins are composed of 3 units, alpha, beta and gamma. Interacts with beta-1 and beta-2, but not with beta-3 (PubMed:7665596). Interacts with KCNK1 (By similarity).
Protein Expression for GNG4 Gene
Post-translational modifications for GNG4 Gene
Other Protein References for GNG4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for GNG4
- Novus Biologicals Antibodies for GNG4
-
Abcam antibodies for GNG4
- Invitrogen Antibodies for GNG4
- Search GeneTex for Antibodies for GNG4
-
Boster Bio Antibodies for GNG4
-
Santa Cruz Biotechnology (SCBT) Antibodies for GNG4
Protein Products
-
OriGene Purified Proteins for GNG4
- Search Origene for MassSpec and Protein Over-expression Lysates for GNG4
- Origene Custom Protein Services for GNG4
- ProSpec Recombinant Proteins for GNG4
- Search GeneTex for Proteins for GNG4
-
Abcam proteins for GNG4
Assay Products
- antibodies-online: Search results for available GNG4 related products ranked by validation data
No data available for DME Specific Peptides for GNG4 Gene
Domains & Families for GNG4 Gene
Gene Families for GNG4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for GNG4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for GNG4 Gene
Graphical View of Domain Structure for InterPro Entry
P50150- Family:
-
- Belongs to the G protein gamma family.
Function for GNG4 Gene
Molecular function for GNG4 Gene
- UniProtKB/Swiss-Prot Function:
- Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Phenotypes From GWAS Catalog for GNG4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 23021213 |
Phenotypes for GNG4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for GNG4
-
CRISPR Products
-
OriGene CRISPR knockouts for GNG4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GNG4
- genomics-online: gRNA clones - Search results for 75 available GNG4 gene related products
- Overview of 75 available GNG4 gene related products
- Applied Biological Materials CRISPR for GNG4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for GNG4
- GenScript: Design CRISPR guide RNA sequences for GNG4
miRNA for GNG4 Gene
- miRTarBase miRNAs that target GNG4
-
- hsa-mir-6513-5p (MIRT523467)
- hsa-mir-887-5p (MIRT523468)
- hsa-mir-3913-5p (MIRT523469)
- hsa-mir-3122 (MIRT523470)
- hsa-mir-450a-1-3p (MIRT523471)
- hsa-mir-6780a-5p (MIRT523472)
- hsa-mir-6779-5p (MIRT523473)
- hsa-mir-3689c (MIRT523474)
- hsa-mir-3689b-3p (MIRT523475)
- hsa-mir-3689a-3p (MIRT523476)
- hsa-mir-30b-3p (MIRT523477)
- hsa-mir-1273h-5p (MIRT523478)
- hsa-mir-6788-5p (MIRT523479)
- hsa-mir-30c-2-3p (MIRT523480)
- hsa-mir-30c-1-3p (MIRT523481)
- hsa-mir-7977 (MIRT523482)
- hsa-mir-3165 (MIRT523483)
- hsa-mir-6745 (MIRT523484)
- hsa-mir-363-5p (MIRT523485)
- hsa-mir-6883-5p (MIRT523486)
- hsa-mir-6785-5p (MIRT523487)
- hsa-mir-4728-5p (MIRT523488)
- hsa-mir-149-3p (MIRT523489)
- hsa-mir-7106-5p (MIRT523490)
- hsa-mir-3656 (MIRT523491)
- hsa-mir-6087 (MIRT523492)
- hsa-mir-6089 (MIRT523493)
- hsa-mir-4738-5p (MIRT523494)
- hsa-mir-1273e (MIRT690540)
- hsa-mir-6516-5p (MIRT690541)
- hsa-mir-455-3p (MIRT690542)
- hsa-mir-6807-5p (MIRT690543)
- hsa-mir-650 (MIRT690544)
- hsa-mir-3612 (MIRT690545)
- hsa-mir-6499-3p (MIRT690546)
- hsa-mir-2467-3p (MIRT690547)
- hsa-mir-6086 (MIRT690548)
- hsa-mir-377-5p (MIRT690549)
- hsa-mir-1827 (MIRT690550)
- hsa-mir-6840-3p (MIRT690551)
- hsa-mir-665 (MIRT690552)
- hsa-mir-4459 (MIRT690553)
- hsa-mir-4257 (MIRT690554)
- hsa-mir-6511a-5p (MIRT690555)
- hsa-mir-1910-3p (MIRT690556)
- hsa-mir-4695-5p (MIRT690557)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GNG4
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- genomics-online: shRNA clones - Search results for 75 available GNG4 gene related products
- Overview of 75 available GNG4 gene related products
Clone Products
-
OriGene ORF clones in human for GNG4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for GNG4
- VectorBuilder custom plasmid, inducible vectors for GNG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GNG4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GNG4
- Applied Biological Materials Clones for GNG4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for GNG4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GNG4 Gene
Localization for GNG4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for GNG4 Gene
- Cell membrane; Lipid-anchor; Cytoplasmic side.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 4 |
| cytosol | 3 |
| mitochondrion | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005834 | heterotrimeric G-protein complex | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0070062 | extracellular exosome | HDA | 23533145 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for GNG4 Gene
Pathways & Interactions for GNG4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Development Angiotensin activation of ERK | ||
| 2 | ADP signalling through P2Y purinoceptor 12 | ||
| 3 | fMLP Pathway |
.43
|
.39
|
| 4 | G-Beta Gamma Signaling |
.46
.44
|
.37
|
| 5 | Presynaptic function of Kainate receptors | ||
Pathways by source for GNG4 Gene
3 BioSystems pathways for GNG4 Gene
55 Reactome pathways for GNG4 Gene
1 PharmGKB pathway for GNG4 Gene
16 KEGG pathways for GNG4 Gene
34 GeneGo (Thomson Reuters) pathways for GNG4 Gene
Interacting Proteins for GNG4 Gene
Selected Interacting proteins:
P50150-GBG4_HUMAN
ENSP00000355556
for GNG4 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for GNG4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | -- |
| GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway | TAS | 7665596 |
| GO:0030308 | negative regulation of cell growth | IMP | 15824735 |
| GO:0071377 | cellular response to glucagon stimulus | TAS | -- |
No data available for SIGNOR curated interactions for GNG4 Gene
Drugs & Compounds for GNG4 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| [D-Trp7,9,10]-Substance P |
|
89430-38-6 |
|
|
||
| G-Protein antagonist peptide |
|
143675-79-0 |
|
|
||
| Gue 1654 |
|
397290-30-1 |
|
|
||
| mastoparan |
|
72093-21-1 |
|
|
||
| SCH 202676 hydrobromide |
|
265980-25-4 |
|
|
(5) Tocris Compounds for GNG4 Gene
| Compound | Action | Cas Number |
|---|---|---|
| [D-Trp7,9,10]-Substance P | Inhibits M1 ACh receptor activation of Gq/11 | 89430-38-6 |
| G-Protein antagonist peptide | Inhibits G protein activation by GPCRs | 143675-79-0 |
| Gue 1654 | Selective inhibitor of OXE-R Gbetagamma signaling | 397290-30-1 |
| Mastoparan | Activates Gi and Go | 72093-21-1 |
| SCH 202676 hydrobromide | Inhibitor of ligand binding to G-protein-coupled receptors | 265980-25-4 |
Drug Products
Transcripts for GNG4 Gene
mRNA/cDNA for GNG4 Gene
- (5) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (150) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000366597 1595 bps (uc057qof.1)
- ENST00000366598 1721 bps (uc001hxh.5)
- ENST00000484517 684 bps (uc057qog.1)
- ENST00000391854 5104 bps (uc001hxe.5)
- ENST00000450593 4978 bps (uc009xfz.4)
Unigene Clusters for GNG4 Gene
- Guanine nucleotide binding protein (G protein), gamma 4:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for GNG4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GNG4
- genomics-online: gRNA clones - Search results for 75 available GNG4 gene related products
- Overview of 75 available GNG4 gene related products
- Applied Biological Materials CRISPR for GNG4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for GNG4
- GenScript: Design CRISPR guide RNA sequences for GNG4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GNG4
- Browse OriGene Inhibitory RNA Products For GNG4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GNG4
- genomics-online: shRNA clones - Search results for 75 available GNG4 gene related products
- Overview of 75 available GNG4 gene related products
Clone Products
-
OriGene ORF clones in human for GNG4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for GNG4
- VectorBuilder custom plasmid, inducible vectors for GNG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GNG4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GNG4
- Applied Biological Materials Clones for GNG4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||
| SP2: | - | ||||||||||||||||
| SP3: | - | - | - | ||||||||||||||
| SP4: |
Expression for GNG4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for GNG4 Gene
This gene is overexpressed in Brain - Hypothalamus (x5.1), Brain - Amygdala (x5.0), Pituitary (x4.1), and Brain - Nucleus accumbens (basal ganglia) (x4.1).
This gene is overexpressed in Retina (21.1), Fetal Brain (14.2), Islet of Langerhans (9.8), Pancreas (8.5), and Ovary (7.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GNG4 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of GNG4 Gene:
GNG4SOURCE GeneReport for Unigene cluster for GNG4 Gene:
Hs.159711mRNA Expression by UniProt/SwissProt for GNG4 Gene:
P50150-GBG4_HUMAN
Tissue specificity:
Brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle.
Evidence on tissue expression from TISSUES for GNG4 Gene
- Nervous system(4.8)
Primer Products
-
OriGene qPCR primer pairs and template standards for GNG4
-
OriGene qPCR primer pairs for GNG4
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for GNG4 Gene
Orthologs for GNG4 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | GNG4 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | GNG4 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | GNG4 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | GNG4 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Gng4 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Gng4 16 34 33 |
|
||
| chicken (Gallus gallus) |
Aves | GNG4 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | GNG4 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | gng4 33 |
|
||
| Str.11936 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.24553 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | gng3 33 |
|
- Species where no ortholog for GNG4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for GNG4 Gene
- ENSEMBL:
- Gene Tree for GNG4 (if available)
- TreeFam:
- Gene Tree for GNG4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GNG4: view image
Paralogs for GNG4 Gene
Variants for GNG4 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000017347 | -- | 235,593,872(-) | G/A | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000033319 | -- | 235,563,622(-) | T/C | intron_variant | |
| rs1000055573 | -- | 235,598,993(-) | C/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000069639 | -- | 235,637,316(-) | A/G | genic_upstream_transcript_variant, intron_variant | |
| rs1000085373 | -- | 235,563,404(-) | A/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv30n21 | CNV | gain | 19592680 |
| esv2471335 | CNV | insertion | 19546169 |
| esv3575794 | CNV | gain | 25503493 |
| esv3589198 | CNV | loss | 21293372 |
| nsv1011288 | CNV | gain | 25217958 |
| nsv1013413 | CNV | gain | 25217958 |
| nsv1013571 | CNV | gain | 25217958 |
| nsv1068233 | CNV | deletion | 25765185 |
| nsv1122460 | CNV | deletion | 24896259 |
| nsv476824 | CNV | novel sequence insertion | 20440878 |
| nsv549392 | CNV | gain | 21841781 |
| nsv832936 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
61.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.09;
1.97% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GNG4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- GNG4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GNG4 Gene
Disorders for GNG4 Gene
Additional Disease Information for GNG4
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for GNG4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GNG4 Gene
Publications for GNG4 Gene
- Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits. (PMID: 7665596) Ray K … Robishaw JD (The Journal of biological chemistry 1995) 2 3 4 58
- Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. (PMID: 17903295) Lunetta KL … Murabito JM (BMC medical genetics 2007) 3 44 58
- Identification of novel VHL target genes and relationship to hypoxic response pathways. (PMID: 15824735) Maina EN … Maher ER (Oncogene 2005) 3 22 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
Products for GNG4 Gene
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- Lentiviral ORF Clones
- Novus Biologicals Antibodies for GNG4
- Novus Biologicals lysates and proteins for GNG4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for GNG4
- Abcam proteins for GNG4
- Find your target
- Browse Primary Antibodies
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- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for GNG4
- VectorBuilder custom plasmid, inducible vectors for GNG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GNG4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 12 available GNG4 Antibodies ranked by validation data
- Compare Top GNG4 Antibodies
- antibodies-online: Search results for available GNG4 related products ranked by validation data
- antibodies-online: Search results for 5 available GNG4 Proteins ranked by validation data
- Compare Top GNG4 Proteins
- Search GeneTex for Antibodies for GNG4
- Search GeneTex for Proteins for GNG4
- Santa Cruz Biotechnology (SCBT) Antibodies for GNG4
- Search Santa Cruz Biotechnology (SCBT) for GNG4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for GNG4
- Horizon Cell Lines for GNG4
- genomics-online: cdna clones - Search results for 75 available GNG4 gene related products
- Overview of 75 available GNG4 gene related products
- orf clones - Search results for 75 available GNG4 gene related products
- Overview of 75 available GNG4 gene related products
- genomics-online: gRNA clones - Search results for 75 available GNG4 gene related products
- Overview of 75 available GNG4 gene related products
- genomics-online: primer clones - Search results for 75 available GNG4 gene related products
- Overview of 75 available GNG4 gene related products
- genomics-online: shRNA clones - Search results for 75 available GNG4 gene related products
- Overview of 75 available GNG4 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GNG4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GNG4
- GeneCopoeia miRNA 3'UTR Target clone products for GNG4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GNG4
- Boster Bio Antibodies for GNG4
- Browse Boster Bio ELISA Kits
Sources for GNG4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt