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Aliases for GNG14 Gene

Aliases for GNG14 Gene

  • G Protein Subunit Gamma 14 2 3 5

External Ids for GNG14 Gene

Summaries for GNG14 Gene

GeneCards Summary for GNG14 Gene

GNG14 (G Protein Subunit Gamma 14) is a Protein Coding gene. An important paralog of this gene is GNG7.

UniProtKB/Swiss-Prot for GNG14 Gene

  • Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Additional gene information for GNG14 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GNG14 Gene

Genomics for GNG14 Gene

Genomic Locations for GNG14 Gene

Genomic Locations for GNG14 Gene
chr19:12,687,444-12,688,820
(GRCh38/hg38)
Size:
1,377 bases
Orientation:
Minus strand

Genomic View for GNG14 Gene

Genes around GNG14 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GNG14 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GNG14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GNG14 Gene

No data available for GeneHancer (GH) Regulatory Elements for GNG14 Gene

Proteins for GNG14 Gene

  • Protein details for GNG14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A1W2PPG7-GBG14_HUMAN
    Recommended name:
    Putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
    Protein Accession:
    A0A1W2PPG7

    Protein attributes for GNG14 Gene

    Size:
    69 amino acids
    Molecular mass:
    7528 Da
    Quaternary structure:
    • G proteins are composed of 3 units; alpha, beta and gamma.

neXtProt entry for GNG14 Gene

Post-translational modifications for GNG14 Gene

No Post-translational modifications

Other Protein References for GNG14 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GNG14 Gene

Domains & Families for GNG14 Gene

Gene Families for GNG14 Gene

Protein Domains for GNG14 Gene

Graphical View of Domain Structure for InterPro Entry

A0A1W2PPG7

UniProtKB/Swiss-Prot:

GBG14_HUMAN :
  • Belongs to the G protein gamma family.
Family:
  • Belongs to the G protein gamma family.
genes like me logo Genes that share domains with GNG14: view

No data available for Suggested Antigen Peptide Sequences for GNG14 Gene

Function for GNG14 Gene

Molecular function for GNG14 Gene

UniProtKB/Swiss-Prot Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Gene Ontology (GO) - Molecular Function for GNG14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004871 signal transducer activity IEA --
genes like me logo Genes that share ontologies with GNG14: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GNG14 Gene

Localization for GNG14 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GNG14 Gene

Cell membrane.

Gene Ontology (GO) - Cellular Components for GNG14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005834 heterotrimeric G-protein complex IEA --
GO:0005886 plasma membrane IEA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with GNG14: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for GNG14 Gene

Pathways & Interactions for GNG14 Gene

SuperPathways for GNG14 Gene

No Data Available

Interacting Proteins for GNG14 Gene

Gene Ontology (GO) - Biological Process for GNG14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with GNG14: view

No data available for Pathways by source and SIGNOR curated interactions for GNG14 Gene

Drugs & Compounds for GNG14 Gene

No Compound Related Data Available

Transcripts for GNG14 Gene

mRNA/cDNA for GNG14 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for GNG14 Gene

No ASD Table

Relevant External Links for GNG14 Gene

GeneLoc Exon Structure for
GNG14
ECgene alternative splicing isoforms for
GNG14

Expression for GNG14 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GNG14 Gene

Orthologs for GNG14 Gene

Evolution for GNG14 Gene

ENSEMBL:
Gene Tree for GNG14 (if available)
TreeFam:
Gene Tree for GNG14 (if available)

No data available for Orthologs for GNG14 Gene

Paralogs for GNG14 Gene

Paralogs for GNG14 Gene

genes like me logo Genes that share paralogs with GNG14: view

Variants for GNG14 Gene

Sequence variations from dbSNP and Humsavar for GNG14 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000454114 -- 12,687,597(+) C/A upstream_transcript_variant
rs1000740503 -- 12,687,190(+) G/A upstream_transcript_variant
rs1001326994 -- 12,686,677(+) G/A upstream_transcript_variant
rs1002010236 -- 12,688,306(+) C/A coding_sequence_variant, synonymous_variant
rs1002194606 -- 12,687,677(+) G/A upstream_transcript_variant

Additional Variant Information for GNG14 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GNG14

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for GNG14 Gene

Disorders for GNG14 Gene

Additional Disease Information for GNG14

No disorders were found for GNG14 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GNG14 Gene

Publications for GNG14 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58
  2. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 58

Products for GNG14 Gene

Sources for GNG14 Gene

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