External Ids for GMIP Gene
Previous GeneCards Identifiers for GMIP Gene
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
GeneCards Summary for GMIP Gene
GMIP (GEM Interacting Protein) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by Rho GTPases. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP29.
UniProtKB/Swiss-Prot Summary for GMIP Gene
Stimulates, in vitro and in vivo, the GTPase activity of RhoA.