External Ids for GMIP Gene
Previous GeneCards Identifiers for GMIP Gene
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
GeneCards Summary for GMIP Gene
GMIP (GEM Interacting Protein) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP45.
UniProtKB/Swiss-Prot Summary for GMIP Gene
Stimulates, in vitro and in vivo, the GTPase activity of RhoA.