Aliases for GMEB2 Gene
External Ids for GMEB2 Gene
Previous GeneCards Identifiers for GMEB2 Gene
This gene is a member of KDWK gene family. The product of this gene associates with GMEB1 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation by the glucocorticoid receptor bound to glucocorticoid response elements. This gene appears to use multiple polyadenylation sites. [provided by RefSeq, Jul 2008]
GeneCards Summary for GMEB2 Gene
GMEB2 (Glucocorticoid Modulatory Element Binding Protein 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and transcription coactivator activity. An important paralog of this gene is GMEB1.
UniProtKB/Swiss-Prot Summary for GMEB2 Gene
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.