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The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] See more...
Aliases for GLYAT Gene
Aliases for GLYAT Gene
External Ids for GLYAT Gene
- HGNC: 13734
- Entrez Gene: 10249
- Ensembl: ENSG00000149124
- OMIM: 607424
- UniProtKB: Q6IB77
Previous GeneCards Identifiers for GLYAT Gene
- GC11M060871
- GC11M059990
- GC11M058727
- GC11M058252
- GC11M058251
- GC11M058232
- GC11M058476
- GC11M054824
- GC11M058728
- GC11M059023
- GC11M059800
Summaries for GLYAT Gene
-
The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for GLYAT Gene
GLYAT (Glycine-N-Acyltransferase) is a Protein Coding gene. Diseases associated with GLYAT include Hairy Tongue and Contractural Arachnodactyly, Congenital. Among its related pathways are Tyrosine metabolism and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring acyl groups and glycine N-benzoyltransferase activity. An important paralog of this gene is GLYATL2.
UniProtKB/Swiss-Prot Summary for GLYAT Gene
-
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Additional gene information for GLYAT Gene
- HGNC(13734)
- Entrez Gene(10249)
- Ensembl(ENSG00000149124)
- OMIM(607424)
- UniProtKB(Q6IB77)
- Open Targets Platform(ENSG00000149124)
- Search for GLYAT at DataMed
- Search for GLYAT at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GLYAT Gene
Genomics for GLYAT Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GLYAT Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH11J058731 | Promoter | 0.7 | EPDnew | 600.7 | +0.0 | 11 | 0.1 | REST SP1 ATF3 YY1 JUND RAD21 HNF4A RXRA MAX HNF4G | GLYAT lnc-GLYATL2-6 CNTF | |
| GH11J058787 | Enhancer | 0.9 | Ensembl ENCODE | 12 | -56.5 | -56472 | 1.3 | CTCF JUND ZNF143 REST RAD21 TRIM22 NFE2 E2F5 YY1 SMC3 | GLYAT GLYATL2 lnc-GLYATL2-3 HSALNG0084366 GLYATL1 | |
| GH11J058762 | Enhancer | 0.8 | ENCODE | 11.7 | -31.1 | -31112 | 1.2 | GATAD2A SOX13 RCOR2 RBFOX2 RXRB IRF2 SP1 CEBPA TCF7 ZKSCAN8 | GLYAT GLYATL2 ENSG00000254926 HSALNG0084366 GLYATL1 | |
| GH11J058675 | Enhancer | 0.6 | ENCODE | 11.6 | +56.2 | 56241 | 0.2 | CTCF ZNF143 REST RAD21 IRF2 TRIM22 ZNF600 RELA CTBP1 RUNX3 | GLYAT CNTF ENSG00000197254 lnc-CNTF-2 ENSG00000280010 | |
| GH11J058674 | Enhancer | 0.2 | ENCODE | 11.6 | +57.2 | 57171 | 0.2 | GLYAT CNTF ENSG00000197254 lnc-CNTF-2 ENSG00000280010 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GLYAT on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GLYAT
- Top Transcription factor binding sites by QIAGEN in the GLYAT gene promoter:
-
- ARP-1
- E47
- HOXA9B
- Meis-1
- Meis-1a
- p53
- POU6F1 (c2)
- RP58
- Tal-1beta
Genomic Locations for GLYAT Gene
Genomic Locations for GLYAT Gene
- chr11:58,640,426-58,731,974
- (GRCh38/hg38)
- Size:
- 91,549 bases
- Orientation:
- Minus strand
- chr11:58,407,899-58,499,447
- (GRCh37/hg19)
- Size:
- 91,549 bases
- Orientation:
- Minus strand
Genomic View for GLYAT Gene
Genes around GLYAT on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q12.1 by HGNC
- 11q12.1 by Entrez Gene
- 11q12.1 by Ensembl
GLYAT Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GLYAT Gene
Proteins for GLYAT Gene
-
Protein details for GLYAT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6IB77-GLYAT_HUMAN
- Recommended name:
- Glycine N-acyltransferase
- Protein Accession:
- Q6IB77
- H1AE11
- O14833
- Q96QK7
Protein attributes for GLYAT Gene
- Size:
- 296 amino acids
- Molecular mass:
- 33924 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAB81453.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAL43174.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
Protein Expression for GLYAT Gene
Selected DME Specific Peptides for GLYAT Gene
- Q6IB77:
-
- CLLGPEGTP
- WHFGGNE
- INWKQHLQIQSSQ
- QMLQMLE
Post-translational modifications for GLYAT Gene
Other Protein References for GLYAT Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-GLYAT monoclonal antibody, clone 2B20
- Creative Biolabs Mouse Anti-GLYAT Recombinant Antibody (1A10)
-
Custom Antibody ServicesOriGene Antibodies for GLYAT
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-
Abcam antibodies for GLYAT
- Invitrogen Antibodies for GLYAT (AFLGC-GLYAT)
-
Biorbyt antibodies for GLYAT
- Sino Biological Antibodies for GLYAT
Protein Products
- Creative Biomart Recombinant Human GLYAT, His-tagged
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- ProSpec Recombinant Proteins for GLYAT
- antibodies-online: Show 10 available GLYAT Proteins ranked by validation data
- Compare Top GLYAT Proteins
-
Quality Products:
-
Signalway Proteins for GLYAT
-
Abcam proteins for GLYAT
Assay Products
- antibodies-online: Show 7 available GLYAT Elisa Kits ranked by validation data
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-
Quality Products:
Domains & Families for GLYAT Gene
Gene Families for GLYAT Gene
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for GLYAT Gene
Suggested Antigen Peptide Sequences for GLYAT Gene
- GenScript: Design optimal peptide antigens:
-
- HRP-1(CLP) (GLYAT_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q6IB77- Family:
-
- Belongs to the glycine N-acyltransferase family.
Function for GLYAT Gene
Molecular function for GLYAT Gene
- UniProtKB/Swiss-Prot Function:
- Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=an acyl-CoA + glycine = an N-acylglycine + CoA + H(+); Xref=Rhea:RHEA:19869, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287, ChEBI:CHEBI:57305, ChEBI:CHEBI:57670, ChEBI:CHEBI:58342; EC=2.3.1.13; Evidence={ECO:0000303|PubMed:22475485, ECO:0000303|PubMed:7802672};.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=benzoyl-CoA + glycine = CoA + H(+) + N-benzoylglycine; Xref=Rhea:RHEA:18493, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287, ChEBI:CHEBI:57305, ChEBI:CHEBI:57369, ChEBI:CHEBI:606565; EC=2.3.1.71; Evidence={ECO:0000303|PubMed:22475485, ECO:0000303|PubMed:7802672};.
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=57.9 mM for benzoyl-CoA {ECO:0000269|PubMed:7802672}; KM=83.7 mM for salicyl-CoA {ECO:0000269|PubMed:7802672}; KM=124 mM for isovaleryl-CoA {ECO:0000269|PubMed:7802672}; KM=198 mM for octanoyl-CoA {ECO:0000269|PubMed:7802672}; Vmax=17.1 umol/min/mg enzyme with benzoyl-CoA as substrate {ECO:0000269|PubMed:7802672}; Vmax=10.1 umol/min/mg enzyme with salicyl-CoA as substrate {ECO:0000269|PubMed:7802672}; Vmax=7.64 umol/min/mg enzyme with isovaleryl-CoA as substrate {ECO:0000269|PubMed:7802672}; Vmax=3.3 umol/min/mg enzyme with octanoyl-CoA as substrate {ECO:0000269|PubMed:7802672};
Enzyme Numbers (IUBMB) for GLYAT Gene
Phenotypes From GWAS Catalog for GLYAT Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0016410 | N-acyltransferase activity | IBA | 21873635 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016746 | transferase activity, transferring acyl groups | TAS | 9202629 |
| GO:0047961 | glycine N-acyltransferase activity | IDA | 22475485 |
Phenotypes for GLYAT Gene
Animal Model Products
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CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for GLYAT - Select products 50% OFF >
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-
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miRNA for GLYAT Gene
- miRTarBase miRNAs that target GLYAT
-
- hsa-miR-498 (MIRT678450)
- hsa-miR-4284 (MIRT678451)
- hsa-miR-6829-3p (MIRT678452)
- hsa-miR-6791-3p (MIRT678453)
- hsa-miR-4772-3p (MIRT678454)
- hsa-miR-4638-5p (MIRT678455)
- hsa-miR-1307-3p (MIRT678456)
- hsa-miR-1976 (MIRT678457)
- hsa-miR-1304-3p (MIRT678458)
- hsa-miR-6741-3p (MIRT678459)
- hsa-miR-1281 (MIRT678460)
- hsa-miR-3193 (MIRT678461)
- hsa-miR-1539 (MIRT678462)
- hsa-miR-660-3p (MIRT678463)
- hsa-miR-4485-5p (MIRT678464)
- hsa-miR-6890-3p (MIRT678465)
- hsa-miR-891a-3p (MIRT679249)
- hsa-miR-5693 (MIRT679250)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GLYAT
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Clone Products
- Applied Biological Materials (abm): Clones for GLYAT - Select products 50% OFF >
- * GLYAT as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for GLYAT
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Cell Line Products
-
Horizon Cell Lines for GLYAT
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GLYAT Gene
Localization for GLYAT Gene
Subcellular locations from UniProtKB/Swiss-Prot for GLYAT Gene
- Mitochondrion.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| nucleus | 3 |
| cytosol | 3 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytoskeleton | 2 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | TAS,ISS | -- |
| GO:0005759 | mitochondrial matrix | TAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for GLYAT Gene
Pathways & Interactions for GLYAT Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Amino Acid conjugation | ||
| 2 | Cytochrome P450 - arranged by substrate type | ||
| 3 | Metabolism |
.40
|
|
| 4 | Tyrosine metabolism | ||
Pathways by source for GLYAT Gene
2 BioSystems pathways for GLYAT Gene
7 Reactome pathways for GLYAT Gene
2 KEGG pathways for GLYAT Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006544 | glycine metabolic process | ISS | -- |
| GO:0006637 | acyl-CoA metabolic process | TAS | 7802672 |
| GO:0006805 | xenobiotic metabolic process | TAS | -- |
| GO:0009636 | response to toxic substance | TAS,IEA | -- |
| GO:0032787 | monocarboxylic acid metabolic process | ISS | -- |
No data available for SIGNOR curated interactions for GLYAT Gene
Drugs & Compounds for GLYAT Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Glycine | Approved, Vet_approved | Nutra | Agonist, Full agonist, Target, substrate | 196 | ||
| Acetylcysteine | Approved, Investigational | Pharma | Antioxidant;mucolytic agent | 427 | ||
| Aminohippuric acid | Approved, Investigational | Pharma | 0 | |||
| Benzoic acid | Approved, Investigational | Pharma | 11 | |||
| n-acetyltyrosine | Approved | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| benzoyl-coa |
|
6756-74-7 | ||||
| (2E)-Decenoyl-CoA |
|
10018-95-8 |
|
|||
| (2E)-Dodecenoyl-CoA |
|
1066-12-2 |
|
|||
| (2E)-Hexadecenoyl-CoA |
|
4460-95-1 |
|
|||
| (2E)-Octenoyl-CoA |
|
10018-94-7 |
|
Drug Products
- Creative Biomart Recombinant Human GLYAT, His-tagged
Transcripts for GLYAT Gene
mRNA/cDNA for GLYAT Gene
- 2 REFSEQ mRNAs :
- 15 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000278400 1150 nts (view in UCSC)
- ENST00000344743 2024 nts (view in UCSC)
- ENST00000529732 1070 nts (view in UCSC)
- ENST00000531084 371 nts (view in UCSC)
- ENST00000586098 482 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for GLYAT - Select products 50% OFF >
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-
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GLYAT
-
Santa Cruz Biotechnology (SCBT) CRISPR for GLYAT
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for GLYAT - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for GLYAT
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GLYAT
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||
| SP3: | - | ||||||||||||||||||||
| SP4: | - |
Relevant External Links for GLYAT Gene
- GeneLoc Exon Structure for
- GLYAT
Expression for GLYAT Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for GLYAT Gene
This gene is overexpressed in Liver (x28.3) and Kidney - Cortex (x21.4).
This gene is overexpressed in Liver (25.1), Liver, secretome (20.3), and Kidney (16.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GLYAT Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GLYAT
SOURCE GeneReport for Unigene cluster for GLYAT Gene:
Hs.145384mRNA Expression by UniProt/SwissProt for GLYAT Gene:
Q6IB77-GLYAT_HUMAN
Tissue specificity:
Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers.
Evidence on tissue expression from TISSUES for GLYAT Gene
- Kidney(4.7)
- Liver(4.7)
- Lung(2.6)
Primer Products
-
OriGene qPCR primer pairs for GLYAT
-
OriGene qPCR primer pairs and template standards for GLYAT
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for GLYAT Gene
Orthologs for GLYAT Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GLYAT 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | GLYAT 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Glyat 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Glyat 30 17 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | GLYAT 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | GLYAT 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100490041 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | si:ch73-106k19.2 31 |
|
ManyToMany |
- Species where no ortholog for GLYAT was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for GLYAT Gene
- ENSEMBL:
- Gene Tree for GLYAT (if available)
- TreeFam:
- Gene Tree for GLYAT (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GLYAT: view image
Paralogs for GLYAT Gene
(4) SIMAP similar genes for GLYAT Gene using alignment to 2 proteins:
- GLYAT_HUMAN
- K7ES21_HUMAN
Pseudogenes.org Pseudogenes for GLYAT Gene
Variants for GLYAT Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GLYAT Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs10896818 | - | p.Ser17Thr | |||
| rs675815 | - | p.Asn156Ser |
Residual Variation Intolerance Score:
88.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.71;
46.43% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GLYAT Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GLYAT Gene
Disorders for GLYAT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hairy tongue |
|
|
| contractural arachnodactyly, congenital |
|
|
| osteogenesis imperfecta, type i |
|
|
| auditory agnosia |
|
|
| isovaleric acidemia |
|
|
Search GLYAT in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for GLYAT
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for GLYAT Gene
Publications for GLYAT Gene
- Genetic polymorphisms of glycine N-acyltransferase in Japanese individuals. (PMID: 19252341) Yamamoto A … Azuma J (Drug metabolism and pharmacokinetics 2009) 3 23 41
- The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase. (PMID: 10630424) van der Westhuizen FH … Erasmus E (Journal of biochemical and molecular toxicology 2000) 3 4 23
- Purification to homogeneity of mitochondrial acyl coa:glycine n-acyltransferase from human liver. (PMID: 7802672) Mawal YR … Qureshi IA (Biochemical and biophysical research communications 1994) 3 4 23
- Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma. (PMID: 22475485) Matsuo M … Kishimoto T (Biochemical and biophysical research communications 2012) 3 4
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 41
ExternalLinks
Products for GLYAT Gene
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- OriGene qPCR primer pairs for GLYAT
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- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for GLYAT
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- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals Antibodies for GLYAT
- Novus Biologicals proteins and lysates for GLYAT
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- Abcam antibodies for GLYAT
- Abcam proteins for GLYAT
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- VectorBuilder Custom and pre-made DNA vectors for GLYAT (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for GLYAT (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for GLYAT (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for GLYAT CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for GLYAT
- antibodies-online: Show 17 available GLYAT Antibodies ranked by validation data
- Compare Top GLYAT Antibodies
- antibodies-online: Show 7 available GLYAT Elisa Kits ranked by validation data
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- antibodies-online: Show 10 available GLYAT Proteins ranked by validation data
- Compare Top GLYAT Proteins
- Quality Products:
- Horizon Cell Lines for GLYAT
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GLYAT
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GLYAT
- Search GeneCopoeia for miRNA 3'UTR Target clone products for GLYAT
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GLYAT
- Biorbyt antibodies for GLYAT
- Signalway Proteins for GLYAT
Sources for GLYAT Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB