Aliases for GLUD2 Gene
External Ids for GLUD2 Gene
Previous HGNC Symbols for GLUD2 Gene
Previous GeneCards Identifiers for GLUD2 Gene
The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.[provided by RefSeq, Jan 2010]
GeneCards Summary for GLUD2 Gene
GLUD2 (Glutamate Dehydrogenase 2) is a Protein Coding gene. Diseases associated with GLUD2 include Parkinson Disease, Late-Onset and Depersonalization Disorder. Among its related pathways are Proximal tubule bicarbonate reclamation and Carbon metabolism. Gene Ontology (GO) annotations related to this gene include GTP binding and ADP binding. An important paralog of this gene is GLUD1.
UniProtKB/Swiss-Prot Summary for GLUD2 Gene
Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission.