External Ids for GLIS1 Gene
Previous GeneCards Identifiers for GLIS1 Gene
GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).[supplied by OMIM, Mar 2008]
GeneCards Summary for GLIS1 Gene
GLIS1 (GLIS Family Zinc Finger 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include RNA polymerase II regulatory region sequence-specific DNA binding and transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding. An important paralog of this gene is GLIS3.
UniProtKB/Swiss-Prot for GLIS1 Gene
Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5-GACCACCCAC-3 (By similarity).