Aliases for GLIPR1 Gene
External Ids for GLIPR1 Gene
Previous GeneCards Identifiers for GLIPR1 Gene
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
GeneCards Summary for GLIPR1 Gene
GLIPR1 (GLI Pathogenesis Related 1) is a Protein Coding gene. Diseases associated with GLIPR1 include Nervous System Cancer and Glioma. Among its related pathways are Innate Immune System and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). An important paralog of this gene is GLIPR1L2.