Aliases for GKAP1 Gene
External Ids for GKAP1 Gene
Previous GeneCards Identifiers for GKAP1 Gene
This gene encodes a protein that is highly similar to the mouse cGMP-dependent protein kinase anchoring protein 42kDa. The mouse protein has been found to localize with the Golgi and recruit cGMP-dependent protein kinase I alpha to the Golgi in mouse testes. It is thought to play a role in germ cell development. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
GeneCards Summary for GKAP1 Gene
GKAP1 (G Kinase Anchoring Protein 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include kinase activity.
UniProtKB/Swiss-Prot Summary for GKAP1 Gene
Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.