Aliases for GK5 Gene
Aliases for GK5 Gene
External Ids for GK5 Gene
- HGNC: 28635
- Entrez Gene: 256356
- Ensembl: ENSG00000175066
- UniProtKB: Q6ZS86
Previous GeneCards Identifiers for GK5 Gene
- GC03M143359
- GC03M141876
- GC03M139249
Summaries for GK5 Gene
GeneCards Summary for GK5 Gene
GK5 (Glycerol Kinase 5 (Putative)) is a Protein Coding gene. Among its related pathways are triacylglycerol biosynthesis and glycerol degradation. Gene Ontology (GO) annotations related to this gene include phosphotransferase activity, alcohol group as acceptor and glycerol kinase activity. An important paralog of this gene is GK3P.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GK5 Gene
Genomics for GK5 Gene
GeneHancer (GH) Regulatory Elements for GK5 Gene
Promoters and enhancers for GK5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around GK5 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for GK5 Gene
Genomic Locations for GK5 Gene
- chr3:142,157,527-142,225,607
- (GRCh38/hg38)
- Size:
- 68,081 bases
- Orientation:
- Minus strand
- chr3:141,876,369-141,944,449
- (GRCh37/hg19)
Genomic View for GK5 Gene
Genes around GK5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q23 by Ensembl
- 3q23 by Entrez Gene
- 3q23 by HGNC
GK5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GK5 Gene
Proteins for GK5 Gene
-
Protein details for GK5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6ZS86-GLPK5_HUMAN
- Recommended name:
- Putative glycerol kinase 5
- Protein Accession:
- Q6ZS86
- B2R9I2
- D3DNG2
- Q8N2A7
- Q8N5E6
Protein attributes for GK5 Gene
- Size:
- 529 amino acids
- Molecular mass:
- 59156 Da
- Quaternary structure:
- No Data Available
Protein Expression for GK5 Gene
Selected DME Specific Peptides for GK5 Gene
- Q6ZS86:
-
- AFRNKQL
- GLAVGFW
- AVKRSMNW
- FGTIDTW
- VPSFSGLQAP
- IRCHVYD
- AMFGECCF
- FHNFISWQDLR
- IFGVPIP
Post-translational modifications for GK5 Gene
Other Protein References for GK5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for GK5
- Novus Biologicals Antibodies for GK5
- Invitrogen Antibodies for GK5
- antibodies-online: Search results for available GK5 related products ranked by validation data
- GeneTex GK5 antibody for GK5
Protein Products
-
OriGene Purified Proteins for GK5
- Search Origene for MassSpec and Protein Over-expression Lysates for GK5
- Origene Custom Protein Services for GK5
- antibodies-online: Search results for available GK5 related products ranked by validation data
- Search GeneTex for Proteins for GK5
-
Abcam proteins for GK5
Assay Products
- antibodies-online: Search results for available GK5 related products ranked by validation data
Domains & Families for GK5 Gene
Gene Families for GK5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for GK5 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for GK5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6ZS86- Family:
-
- Belongs to the FGGY kinase family.
Function for GK5 Gene
Molecular function for GK5 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + glycerol = ADP + sn-glycerol 3-phosphate.
Enzyme Numbers (IUBMB) for GK5 Gene
Phenotypes From GWAS Catalog for GK5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004370 | glycerol kinase activity | IBA | -- |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0016301 | kinase activity | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | IEA | -- |
Phenotypes for GK5 Gene
- GenomeRNAi human phenotypes for GK5:
Animal Model Products
-
Taconic Biosciences Mouse Models for GK5
- Cyagen custom Knockout/knockin (KOKI) mouse models for GK5
-
-
ViGene Biosciences lentiviral particle packaged cDNA for GK5 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for GK5 gene
- Search ViGene Biosciences for GK5
CRISPR Products
-
OriGene CRISPR knockouts for GK5
- genomics-online: gRNA clones - Search results for 83 available GK5 gene related products
- Overview of 83 available GK5 gene related products
- Applied Biological Materials CRISPR for GK5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for GK5
- GenScript: Design CRISPR guide RNA sequences for GK5
miRNA for GK5 Gene
- miRTarBase miRNAs that target GK5
-
- hsa-mir-340-5p (MIRT019547)
- hsa-mir-124-3p (MIRT022437)
- hsa-mir-21-5p (MIRT090589)
- hsa-mir-4279 (MIRT161216)
- hsa-mir-5571-5p (MIRT400471)
- hsa-mir-374a-5p (MIRT440567)
- hsa-mir-6809-3p (MIRT613735)
- hsa-mir-6833-3p (MIRT613736)
- hsa-mir-4768-5p (MIRT613737)
- hsa-mir-6873-3p (MIRT613738)
- hsa-mir-4753-3p (MIRT613739)
- hsa-mir-130b-5p (MIRT613740)
- hsa-mir-7110-3p (MIRT613741)
- hsa-mir-6817-3p (MIRT613742)
- hsa-mir-3160-5p (MIRT616290)
- hsa-mir-4668-5p (MIRT623788)
- hsa-mir-145-3p (MIRT623789)
- hsa-mir-5572 (MIRT623790)
- hsa-mir-4260 (MIRT623791)
- hsa-mir-450a-2-3p (MIRT623792)
- hsa-mir-1227-5p (MIRT623793)
- hsa-mir-185-3p (MIRT623794)
- hsa-mir-4283 (MIRT623795)
- hsa-mir-4489 (MIRT623796)
- hsa-mir-3649 (MIRT623797)
- hsa-mir-6778-3p (MIRT623798)
- hsa-mir-150-5p (MIRT623799)
- hsa-mir-6787-3p (MIRT623800)
- hsa-mir-6814-5p (MIRT623801)
- hsa-mir-3691-3p (MIRT623802)
- hsa-mir-6740-5p (MIRT632883)
- hsa-mir-7703 (MIRT635270)
- hsa-mir-6720-5p (MIRT635271)
- hsa-mir-6512-3p (MIRT635272)
- hsa-mir-196a-3p (MIRT635273)
- hsa-mir-661 (MIRT635274)
- hsa-mir-4252 (MIRT635275)
- hsa-mir-6076 (MIRT635276)
- hsa-mir-6797-3p (MIRT635277)
- hsa-mir-6860 (MIRT635278)
- hsa-mir-612 (MIRT635279)
- hsa-mir-5189-5p (MIRT635280)
- hsa-mir-3187-5p (MIRT635281)
- hsa-mir-1285-3p (MIRT635282)
- hsa-mir-4793-3p (MIRT635283)
- hsa-mir-766-3p (MIRT635284)
- hsa-mir-939-3p (MIRT635285)
- hsa-mir-6849-3p (MIRT635286)
- hsa-mir-1273g-3p (MIRT635287)
- hsa-mir-6501-3p (MIRT635288)
- hsa-mir-508-5p (MIRT635289)
- hsa-mir-6084 (MIRT638645)
- hsa-mir-3194-5p (MIRT638646)
- hsa-mir-6821-3p (MIRT638647)
- hsa-mir-4454 (MIRT638648)
- hsa-mir-6790-3p (MIRT638649)
- hsa-mir-1976 (MIRT638650)
- hsa-mir-3653-5p (MIRT638651)
- hsa-mir-498 (MIRT657787)
- hsa-mir-5699-3p (MIRT657788)
- hsa-mir-4421 (MIRT657789)
- hsa-mir-6748-3p (MIRT657790)
- hsa-mir-6845-3p (MIRT657791)
- hsa-mir-4685-3p (MIRT657792)
- hsa-mir-4287 (MIRT657793)
- hsa-mir-5088-3p (MIRT657794)
- hsa-mir-1207-3p (MIRT657795)
- hsa-mir-4639-3p (MIRT657796)
- hsa-mir-3617-3p (MIRT657797)
- hsa-mir-603 (MIRT657798)
- hsa-mir-182-5p (MIRT668093)
- hsa-mir-4470 (MIRT668094)
- hsa-mir-6747-3p (MIRT668095)
- hsa-mir-6727-3p (MIRT668096)
- hsa-mir-4722-3p (MIRT668097)
- hsa-mir-890 (MIRT668098)
- hsa-mir-4449 (MIRT668099)
- hsa-mir-4284 (MIRT668100)
- hsa-mir-4772-3p (MIRT668101)
- hsa-mir-4638-5p (MIRT668102)
- hsa-mir-1307-3p (MIRT668103)
- hsa-mir-1304-3p (MIRT668104)
- hsa-mir-6741-3p (MIRT668105)
- hsa-mir-4532 (MIRT668106)
- hsa-mir-1247-3p (MIRT668107)
- hsa-mir-6890-3p (MIRT668108)
- hsa-mir-5698 (MIRT668109)
- hsa-mir-744-3p (MIRT668110)
- hsa-mir-874-3p (MIRT668111)
- hsa-mir-3157-3p (MIRT668112)
- hsa-mir-4423-5p (MIRT668113)
- hsa-mir-6501-5p (MIRT668114)
- hsa-mir-891a-3p (MIRT668115)
- hsa-mir-143-5p (MIRT668116)
- hsa-mir-4430 (MIRT668117)
- hsa-mir-3652 (MIRT668118)
- hsa-mir-122-5p (MIRT668119)
- hsa-mir-504-3p (MIRT668120)
- hsa-mir-3135b (MIRT668121)
- hsa-mir-146b-3p (MIRT668122)
- hsa-mir-6799-3p (MIRT668123)
- hsa-mir-3173-5p (MIRT668124)
- hsa-mir-7976 (MIRT668125)
- hsa-mir-6499-3p (MIRT668126)
- hsa-mir-367-5p (MIRT668127)
- hsa-mir-1915-5p (MIRT668128)
- hsa-mir-5693 (MIRT668129)
- hsa-mir-6749-3p (MIRT668130)
- hsa-mir-5089-5p (MIRT688097)
- hsa-mir-6878-3p (MIRT688098)
- hsa-mir-6807-5p (MIRT688099)
- hsa-mir-7151-3p (MIRT688100)
- hsa-mir-5095 (MIRT688101)
- hsa-mir-6744-3p (MIRT688102)
- hsa-mir-4757-5p (MIRT688103)
- hsa-mir-5589-5p (MIRT688104)
- hsa-mir-4731-5p (MIRT688105)
- hsa-mir-6506-5p (MIRT688106)
- hsa-mir-619-5p (MIRT688107)
- hsa-mir-186-3p (MIRT688108)
- hsa-mir-520h (MIRT688109)
- hsa-mir-520g-3p (MIRT688110)
- hsa-mir-6504-3p (MIRT688111)
- hsa-mir-512-3p (MIRT688112)
- hsa-mir-4438 (MIRT688113)
- hsa-mir-6818-3p (MIRT708125)
- hsa-mir-4684-5p (MIRT708126)
- hsa-mir-593-3p (MIRT708127)
- hsa-mir-6895-3p (MIRT708128)
- hsa-mir-339-5p (MIRT708129)
- hsa-mir-10b-5p (MIRT708130)
- hsa-mir-10a-5p (MIRT708131)
- hsa-mir-6732-3p (MIRT708132)
- hsa-mir-548ay-3p (MIRT708133)
- hsa-mir-548at-3p (MIRT708134)
- hsa-mir-548as-3p (MIRT708135)
- hsa-mir-548t-3p (MIRT708136)
- hsa-mir-548ap-3p (MIRT708137)
- hsa-mir-548aa (MIRT708138)
- hsa-mir-548c-3p (MIRT708139)
- hsa-mir-181c-5p (MIRT727575)
- hsa-mir-181d-5p (MIRT727576)
- hsa-mir-181b-5p (MIRT727577)
- hsa-mir-181a-5p (MIRT727578)
miRNA Products
- Search ViGene Biosciences for GK5
Inhibitory RNA Products
- Origene sirna and shrna products in human, mouse, rat for GK5
- Browse OriGene Inhibitory RNA Products For GK5
- genomics-online: shRNA clones - Search results for 83 available GK5 gene related products
- Overview of 83 available GK5 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for GK5 gene
Clone Products
- Sino Biological Human cDNA Clone for GK5
- VectorBuilder custom plasmid, inducible vectors for GK5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GK5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for GK5
- Applied Biological Materials Clones for GK5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for GK5
-
ViGene Biosciences adenoviral particle packaged cDNA for GK5 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for GK5 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for GK5 gene
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GK5 Gene
Localization for GK5 Gene
| Compartment | Confidence |
|---|---|
| mitochondrion | 3 |
| nucleus | 3 |
| cytosol | 3 |
| peroxisome | 2 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IBA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for GK5 Gene
Pathways & Interactions for GK5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | triacylglycerol biosynthesis | ||
| 2 | glycerol degradation | ||
Pathways by source for GK5 Gene
2 BioSystems pathways for GK5 Gene
UniProtKB/Swiss-Prot Q6ZS86-GLPK5_HUMAN
- Pathway: Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
Interacting Proteins for GK5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005975 | carbohydrate metabolic process | IEA | -- |
| GO:0006071 | glycerol metabolic process | IBA | -- |
| GO:0006641 | triglyceride metabolic process | IBA | -- |
| GO:0016310 | phosphorylation | IEA | -- |
| GO:0019563 | glycerol catabolic process | IEA | -- |
No data available for SIGNOR curated interactions for GK5 Gene
Drugs & Compounds for GK5 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| ADP |
|
Full agonist, Agonist | 58-64-0 |
|
||
| glycerol 3-phosphate |
|
57-03-4 |
|
Transcripts for GK5 Gene
mRNA/cDNA for GK5 Gene
- (6) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (64) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for GK5 Gene
CRISPR Products
-
OriGene CRISPR knockouts for GK5
- genomics-online: gRNA clones - Search results for 83 available GK5 gene related products
- Overview of 83 available GK5 gene related products
- Applied Biological Materials CRISPR for GK5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for GK5
- GenScript: Design CRISPR guide RNA sequences for GK5
miRNA Products
- Search ViGene Biosciences for GK5
Inhibitory RNA Products
- Origene sirna and shrna products in human, mouse, rat for GK5
- Browse OriGene Inhibitory RNA Products For GK5
- genomics-online: shRNA clones - Search results for 83 available GK5 gene related products
- Overview of 83 available GK5 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for GK5 gene
Clone Products
- Sino Biological Human cDNA Clone for GK5
- VectorBuilder custom plasmid, inducible vectors for GK5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GK5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for GK5
- Applied Biological Materials Clones for GK5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP3: |
Expression for GK5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Ovary (Reproductive System)
- Mature Granulosa Cells Antral Follicle
-
Blood (Hematopoietic System)
- Natural Killer Cells Peripheral Blood
This gene is overexpressed in Fetal gut (62.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for GK5 Gene
NURSA nuclear receptor signaling pathways regulating expression of GK5 Gene:
GK5SOURCE GeneReport for Unigene cluster for GK5 Gene:
Hs.135904Evidence on tissue expression from TISSUES for GK5 Gene
- Nervous system(4.2)
- Kidney(4.1)
- Blood(4)
Primer Products
-
OriGene qPCR primer pairs for GK5
- genomics-online: primer clones - Search results for 83 available GK5 gene related products
- Overview of 83 available GK5 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GK5 Gene
Orthologs for GK5 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | GK5 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | GK5 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | GK5 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Gk5 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Gk5 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | GK5 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | GK5 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | GK5 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | GK5 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | gk5 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | gk5 33 34 |
|
||
| wufc06f04 33 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007581 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG1271 33 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | C55B6.1 33 34 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | GUT1 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.533 33 |
|
- Species where no ortholog for GK5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for GK5 Gene
(3) SIMAP similar genes for GK5 Gene using alignment to 4 proteins:
Variants for GK5 Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000004815 | -- | 142,182,069(-) | G/A | intron_variant | |
| rs1000067798 | -- | 142,188,284(-) | C/T | intron_variant | |
| rs1000087489 | -- | 142,195,213(-) | T/C | intron_variant | |
| rs1000197648 | -- | 142,218,847(-) | T/C | intron_variant | |
| rs1000210995 | -- | 142,220,850(-) | A/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1412e212 | CNV | gain | 25503493 |
| dgv299n21 | CNV | gain | 19592680 |
| dgv4912n100 | CNV | gain | 25217958 |
| dgv619n27 | CNV | gain | 19166990 |
| dgv8625n54 | CNV | gain | 21841781 |
| dgv8626n54 | CNV | gain | 21841781 |
| esv2751979 | CNV | gain | 17911159 |
| esv2759182 | CNV | gain | 17122850 |
| esv2763767 | CNV | gain | 21179565 |
| esv34483 | CNV | gain | 17911159 |
| esv3597995 | CNV | gain | 21293372 |
| esv3597996 | CNV | gain | 21293372 |
| esv3598001 | CNV | gain | 21293372 |
| nsv1002953 | CNV | loss | 25217958 |
| nsv1008873 | CNV | gain | 25217958 |
| nsv1011175 | CNV | gain | 25217958 |
| nsv523945 | CNV | gain | 19592680 |
Residual Variation Intolerance Score:
14.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.82;
17.26% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GK5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- GK5
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GK5 Gene
Disorders for GK5 Gene
Additional Disease Information for GK5
No disorders were found for GK5 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GK5 Gene
Publications for GK5 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
- MicroRNA-135b exerts oncogenic activity in glioblastoma via the inhibition of glycerol kinase 5 expression. (PMID: 25936394) Yu Y … Zhang BZ (Molecular medicine reports 2015) 3 58
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K … Gorospe M (The EMBO journal 2009) 3 58
- The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 4 58
Products for GK5 Gene
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- Custom Antibody ServicesOriGene Antibodies for GK5
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- Taconic Biosciences Mouse Models for GK5
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- VectorBuilder custom plasmid, inducible vectors for GK5
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for GK5
- antibodies-online: Search results for available GK5 related products ranked by validation data
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- GeneTex GK5 antibody for GK5
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- ViGene Biosciences adenoviral particle packaged cDNA for GK5 gene
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- Horizon Cell Lines for GK5
- genomics-online: cdna clones - Search results for 83 available GK5 gene related products
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- Overview of 83 available GK5 gene related products
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- Overview of 83 available GK5 gene related products
- genomics-online: shRNA clones - Search results for 83 available GK5 gene related products
- Overview of 83 available GK5 gene related products
Sources for GK5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
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- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
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- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
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- (114) diseasecard
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- (135) Horizon
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- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
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- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
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- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
