Aliases for GK3P Gene

Aliases for GK3P Gene

  • Glycerol Kinase 3 Pseudogene 2 3 4 5
  • GKTB 2 3 4
  • Glycerol Kinase Pseudogene 3 2 3
  • EC 4 51
  • GKP3 3 4
  • ATP:Glycerol 3-Phosphotransferase 3 4
  • Glycerol Kinase, Testis Specific 1 4
  • Glycerol Kinase 3 4
  • Glycerokinase 3 4
  • GK3P 5
  • GK 3 4

External Ids for GK3P Gene

Previous HGNC Symbols for GK3P Gene

  • GKP3

Previous GeneCards Identifiers for GK3P Gene

  • GC04M166420
  • GC04M166198
  • GC04M161950

Summaries for GK3P Gene

GeneCards Summary for GK3P Gene

GK3P (Glycerol Kinase 3 Pseudogene) is a Pseudogene. Diseases associated with GK3P include Glycerol Kinase 3 Pseudogene. An important paralog of this gene is GK.

UniProtKB/Swiss-Prot Summary for GK3P Gene

Additional gene information for GK3P Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GK3P Gene

Genomics for GK3P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for GK3P Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J165279 Enhancer 0.2 Ensembl 600.7 -0.5 -478 0.6 GK3P RF00004-094 MSMO1 TMEM192 KLHL2
GH04J165273 Enhancer 0.3 Ensembl 0.4 +6.0 6022 0.8 TRIM28 KLHL2 piR-55194-282 GK3P MSMO1 TMEM192
GH04J165275 Enhancer 0.2 Ensembl 0.7 +4.7 4722 1 KLHL2 GK3P piR-55194-282 MSMO1 TMEM192
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GK3P on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the GK3P gene promoter:
  • AML1a
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • NRSF form 1
  • NRSF form 2
  • SRF (504 AA)

Genomic Locations for GK3P Gene

Genomic Locations for GK3P Gene
2,232 bases
Minus strand
2,232 bases
Minus strand

Genomic View for GK3P Gene

Genes around GK3P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GK3P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GK3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GK3P Gene

Proteins for GK3P Gene

  • Protein details for GK3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Glycerol kinase 3
    Protein Accession:
    Secondary Accessions:
    • Q6NXP9

    Protein attributes for GK3P Gene

    553 amino acids
    Molecular mass:
    60598 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GK3P Gene

Selected DME Specific Peptides for GK3P Gene


Post-translational modifications for GK3P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GK3P Gene

ENSEMBL proteins:

Domains & Families for GK3P Gene

Gene Families for GK3P Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Predicted membrane proteins

Protein Domains for GK3P Gene

Suggested Antigen Peptide Sequences for GK3P Gene

GenScript: Design optimal peptide antigens:
  • Glycerol kinase, testis specific 1 (GLPK3_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FGGY kinase family.
  • Belongs to the FGGY kinase family.
genes like me logo Genes that share domains with GK3P: view

Function for GK3P Gene

Molecular function for GK3P Gene

UniProtKB/Swiss-Prot Function:
Key enzyme in the regulation of glycerol uptake and metabolism.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate; Xref=Rhea:RHEA:21644, ChEBI:CHEBI:15378, ChEBI:CHEBI:17754, ChEBI:CHEBI:30616, ChEBI:CHEBI:57597, ChEBI:CHEBI:456216; EC=;.

Enzyme Numbers (IUBMB) for GK3P Gene

Gene Ontology (GO) - Molecular Function for GK3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0004370 glycerol kinase activity IBA --
GO:0005524 ATP binding IEA --
GO:0016301 kinase activity IEA --
GO:0016740 transferase activity IEA --
genes like me logo Genes that share ontologies with GK3P: view

Phenotypes for GK3P Gene

genes like me logo Genes that share phenotypes with GK3P: view

Animal Model Products

CRISPR Products

No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GK3P Gene

Localization for GK3P Gene

Subcellular locations from UniProtKB/Swiss-Prot for GK3P Gene

Mitochondrion outer membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm. Note=In sperm the majority of the enzyme is bound to mitochondria. {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for GK3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005739 mitochondrion IBA --
GO:0005741 mitochondrial outer membrane IEA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with GK3P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for GK3P Gene

Pathways & Interactions for GK3P Gene

PathCards logo

SuperPathways for GK3P Gene

No Data Available

UniProtKB/Swiss-Prot Q14409-GLPK3_HUMAN

  • Pathway: Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Interacting Proteins for GK3P Gene

Gene Ontology (GO) - Biological Process for GK3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005975 carbohydrate metabolic process IEA --
GO:0006071 glycerol metabolic process IBA --
GO:0006072 glycerol-3-phosphate metabolic process IEA --
GO:0006641 triglyceride metabolic process IBA --
GO:0016310 phosphorylation IBA --
genes like me logo Genes that share ontologies with GK3P: view

No data available for Pathways by source and SIGNOR curated interactions for GK3P Gene

Drugs & Compounds for GK3P Gene

(2) Drugs for GK3P Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Glycerol Approved, Investigational Pharma 197
ATP Investigational Nutra Agonist, Activator, Partial agonist, Antagonist, Full agonist, Gating inhibitor, Pore Blocker, Potentiation 0

(2) Additional Compounds for GK3P Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • 5'-Adenylphosphoric acid
  • Adenosine 5'-diphosphate
  • ADENOSINE-5'-diphosphATE
  • H3ADP
  • 5'-Adenylphosphate
Agonist, Full agonist, Partial agonist, Gating inhibitor, Antagonist 58-64-0
glycerol 3-phosphate
  • (R)-Glycerol 1-phosphate
  • D-(Glycerol 1-phosphate)
  • D-Glycerol 1-phosphate
  • Glycerol-3-phosphate
  • Glycerophosphoric acid
genes like me logo Genes that share compounds with GK3P: view

Transcripts for GK3P Gene

mRNA/cDNA for GK3P Gene

4 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for GK3P Gene

No ASD Table

Relevant External Links for GK3P Gene

GeneLoc Exon Structure for

Expression for GK3P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GK3P Gene

mRNA differential expression in normal tissues according to GTEx for GK3P Gene

This gene is overexpressed in Testis (x20.6), Whole Blood (x9.6), and Liver (x4.9).

Protein differential expression in normal tissues from HIPED for GK3P Gene

This gene is overexpressed in Peripheral blood mononuclear cells (47.4), Testis (10.7), and Heart (8.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GK3P Gene

Protein tissue co-expression partners for GK3P Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GK3P

SOURCE GeneReport for Unigene cluster for GK3P Gene:

genes like me logo Genes that share expression patterns with GK3P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GK3P Gene

Orthologs for GK3P Gene

Evolution for GK3P Gene

Gene Tree for GK3P (if available)
Gene Tree for GK3P (if available)

No data available for Orthologs for GK3P Gene

Paralogs for GK3P Gene

Paralogs for GK3P Gene

(3) SIMAP similar genes for GK3P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with GK3P: view

Variants for GK3P Gene

Structural Variations from Database of Genomic Variants (DGV) for GK3P Gene

Variant ID Type Subtype PubMed ID
nsv967810 CNV duplication 23825009
nsv967811 CNV duplication 23825009

Additional Variant Information for GK3P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for GK3P Gene

Disorders for GK3P Gene

MalaCards: The human disease database

(1) MalaCards diseases for GK3P Gene - From: GeneCards

Disorder Aliases PubMed IDs
glycerol kinase 3 pseudogene
  • gk3p
- elite association - COSMIC cancer census association via MalaCards
Search GK3P in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with GK3P: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GK3P Gene

Publications for GK3P Gene

  1. The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons. (PMID: 7987308) Sargent CA … Affara NA (Human molecular genetics 1994) 2 3 4
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for GK3P Gene

Sources for GK3P Gene