Aliases for GK Gene
External Ids for GK Gene
Previous GeneCards Identifiers for GK Gene
The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
GeneCards Summary for GK Gene
GK (Glycerol Kinase) is a Protein Coding gene. Diseases associated with GK include Glycerol Kinase Deficiency and Adrenal Hypoplasia, Congenital. Among its related pathways are Mitochondrial LC-Fatty Acid Beta-Oxidation and triacylglycerol biosynthesis. Gene Ontology (GO) annotations related to this gene include kinase activity and glycerol kinase activity. An important paralog of this gene is GK3P.
UniProtKB/Swiss-Prot Summary for GK Gene
Key enzyme in the regulation of glycerol uptake and metabolism.