Aliases for GK Gene
External Ids for GK Gene
Previous GeneCards Identifiers for GK Gene
The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
GeneCards Summary for GK Gene
GK (Glycerol Kinase) is a Protein Coding gene. Diseases associated with GK include Glycerol Kinase Deficiency and Adrenal Hypoplasia, Congenital. Among its related pathways are triacylglycerol biosynthesis and glycerol degradation. Gene Ontology (GO) annotations related to this gene include kinase activity and glycerol kinase activity. An important paralog of this gene is GK3P.
UniProtKB/Swiss-Prot Summary for GK Gene
Key enzyme in the regulation of glycerol uptake and metabolism.