Aliases for GINS3 Gene
External Ids for GINS3 Gene
Previous GeneCards Identifiers for GINS3 Gene
This gene encodes a protein subunit of the GINS heterotetrameric complex, which is essential for the initiation of DNA replication and replisome progression in eukaryotes. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for GINS3 Gene
GINS3 (GINS Complex Subunit 3) is a Protein Coding gene. Diseases associated with GINS3 include Nk Cell Deficiency. Among its related pathways are Cell Cycle, Mitotic and Telomere C-strand (Lagging Strand) Synthesis.
UniProtKB/Swiss-Prot Summary for GINS3 Gene
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.