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This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
GIMAP7 (GTPase, IMAP Family Member 7) is a Protein Coding gene. Diseases associated with GIMAP7 include Epileptic Encephalopathy, Early Infantile, 4. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and GTPase activity. An important paralog of this gene is GIMAP1-GIMAP5.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000166 | nucleotide binding | IEA | -- |
GO:0003924 | GTPase activity | IDA | 23454188 |
GO:0005515 | protein binding | IPI | 23454188 |
GO:0005525 | GTP binding | IDA | 23454188 |
GO:0042802 | identical protein binding | IPI | 23454188 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IEA | -- |
GO:0005783 | endoplasmic reticulum | IEA | -- |
GO:0005794 | Golgi apparatus | IEA | -- |
GO:0005811 | lipid droplet | IEA,IDA | 23454188 |
GO:0005829 | cytosol | IBA,IDA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0046039 | GTP metabolic process | IDA | 23454188 |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Guanosine triphosphate | Experimental | Pharma | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
N1-acetylspermine |
|
25593-72-0 |
|
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | GIMAP7 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | GIMAP7 30 31 31 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Dog (Canis familiaris) |
Mammalia | GIMAP7 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Gimap7 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Gimap7 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Chicken (Gallus gallus) |
Aves | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Zebrafish (Danio rerio) |
Actinopterygii | CU550714.1 31 |
|
ManyToMany | |
si:ch211-254c8.3 31 |
|
ManyToMany | |||
CR933791.1 31 |
|
ManyToMany | |||
CR450842.1 31 |
|
ManyToMany | |||
BX323987.1 31 |
|
ManyToMany | |||
CR933791.3 31 |
|
ManyToMany | |||
si:dkeyp-67a8.4 31 31 |
|
ManyToMany | |||
zgc:172131 31 |
|
ManyToMany | |||
BX322792.2 31 |
|
ManyToMany | |||
CU695221.1 31 |
|
ManyToMany | |||
zgc:152753 31 |
|
ManyToMany | |||
BX005442.2 31 |
|
ManyToMany | |||
zgc:101806 31 |
|
ManyToMany | |||
si:ch211-280c16.1 31 |
|
ManyToMany | |||
zgc:165583 31 |
|
ManyToMany | |||
BX322792.1 31 |
|
ManyToMany | |||
zgc:195075 31 |
|
ManyToMany | |||
BX004816.3 31 |
|
ManyToMany | |||
BX004857.2 31 |
|
ManyToMany | |||
si:ch73-308m11.1 31 |
|
ManyToMany | |||
zgc:172090 31 |
|
ManyToMany | |||
CABZ01029902.1 31 |
|
ManyToMany | |||
si:dkey-30g5.1 31 |
|
ManyToMany | |||
si:ch1073-185p12.2 31 |
|
ManyToMany | |||
BX321875.5 31 31 |
|
ManyToMany |
SNP ID | Clinical significance and condition | Chr 07 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs3735080 | - | p.Arg83Cys |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv3695n106 | OTHER | inversion | 24896259 |
nsv1015582 | CNV | gain | 25217958 |
nsv1031309 | CNV | loss | 25217958 |
nsv1034409 | CNV | gain | 25217958 |
nsv1067934 | OTHER | inversion | 25765185 |
nsv1151906 | OTHER | inversion | 26484159 |
nsv608990 | CNV | gain | 21841781 |
Disorder | Aliases | PubMed IDs |
---|---|---|
epileptic encephalopathy, early infantile, 4 |
|
|