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Aliases for GHRLOS Gene

Subcategory (RNA class) for GHRLOS Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for GHRLOS Gene

  • Ghrelin Opposite Strand/Antisense RNA 2 3 5
  • GHRL Antisense RNA 1 (Non-Protein Coding) 2 3
  • Ghrelin Opposite Strand/Antisense RNA (Non-Protein Coding) 2
  • Ghrelin Opposite Strand RNA (Non-Protein Coding) 2
  • Non-Protein Coding RNA 68 2
  • NCRNA00068 3
  • GHRL-AS1 3
  • GHRLAS 3

External Ids for GHRLOS Gene

Previous GeneCards Identifiers for GHRLOS Gene

  • GC03U900879
  • GC03P010327
  • GC03P010284
  • GC03P010428
  • GC03P010452
  • GC03P010478
  • GC03P010506
  • GC03P010535
  • GC03P010563
  • GC03P010591

Summaries for GHRLOS Gene

Entrez Gene Summary for GHRLOS Gene

  • This gene is an antisense gene of the ghrelin/obestatin prepropeptide gene. Alternatively spliced transcript variants have been identified and they may function as non-coding regulatory RNAs. [provided by RefSeq, Jan 2013]

GeneCards Summary for GHRLOS Gene

GHRLOS (Ghrelin Opposite Strand/Antisense RNA) is an RNA Gene, and is affiliated with the non-coding RNA class.

Gene Wiki entry for GHRLOS Gene

Additional gene information for GHRLOS Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GHRLOS Gene

Genomics for GHRLOS Gene

GeneHancer (GH) Regulatory Elements for GHRLOS Gene

Promoters and enhancers for GHRLOS Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J010279 Promoter 0.5 EPDnew 650.7 -1.6 -1591 0.1 GC03P010636 GHRLOS PIR38232 PIR46498 PIR32303 PIR50872 TATDN2 ENSG00000272410
GH03J010280 Promoter 0.5 EPDnew 650.7 -0.2 -188 0.1 GHRLOS PIR50872 PIR32303 PIR46498 TATDN2 ENSG00000272410
GH03J010188 Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 48.1 -86.1 -86107 12.1 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A ZNF2 ZBTB7B YY1 POLR2B BRPF1 SETD5 IRAK2 GHRLOS LINC00852 TATDN2 FANCD2 GHRL TTLL3 SEC13
GH03J009394 Promoter/Enhancer 1.8 Ensembl ENCODE dbSUPER 41 -882.0 -881961 9.8 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SETD5 THUMPD3-AS1 GC03P009403 BRPF1 RAD18 TTLL3 GHRLOS FANCD2 SRGAP3-AS3 JAGN1
GH03J009889 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 31.1 -390.1 -390134 2.4 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 POLR2B JAGN1 CIDEC BRPF1 RAD18 SETD5 FANCD2 LINC00852 TTLL3 GHRLOS SEC13
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GHRLOS on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the GHRLOS gene promoter:
  • AP-1
  • c-Jun
  • ATF-2
  • deltaCREB
  • CREB
  • c-Fos
  • PPAR-gamma2

Genomic Locations for GHRLOS Gene

Genomic Locations for GHRLOS Gene
chr3:10,280,952-10,293,449
(GRCh38/hg38)
Size:
12,498 bases
Orientation:
Plus strand
chr3:10,327,438-10,335,133
(GRCh37/hg19)
Size:
7,696 bases
Orientation:
Plus strand

Genomic View for GHRLOS Gene

Genes around GHRLOS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GHRLOS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GHRLOS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GHRLOS Gene

Proteins for GHRLOS Gene

Post-translational modifications for GHRLOS Gene

No Post-translational modifications

No data available for DME Specific Peptides for GHRLOS Gene

Domains & Families for GHRLOS Gene

Gene Families for GHRLOS Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GHRLOS: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GHRLOS Gene

Function for GHRLOS Gene

Phenotypes From GWAS Catalog for GHRLOS Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GHRLOS Gene

Localization for GHRLOS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GHRLOS Gene

Pathways & Interactions for GHRLOS Gene

SuperPathways for GHRLOS Gene

No Data Available

Interacting Proteins for GHRLOS Gene

Gene Ontology (GO) - Biological Process for GHRLOS Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GHRLOS Gene

Drugs & Compounds for GHRLOS Gene

No Compound Related Data Available

Transcripts for GHRLOS Gene

mRNA/cDNA for GHRLOS Gene

(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(10) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for GHRLOS Gene

No ASD Table

Relevant External Links for GHRLOS Gene

GeneLoc Exon Structure for
GHRLOS
ECgene alternative splicing isoforms for
GHRLOS

Expression for GHRLOS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GHRLOS Gene

mRNA differential expression in normal tissues according to GTEx for GHRLOS Gene

This gene is overexpressed in Stomach (x6.6).

NURSA nuclear receptor signaling pathways regulating expression of GHRLOS Gene:

GHRLOS
genes like me logo Genes that share expression patterns with GHRLOS: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GHRLOS Gene

Orthologs for GHRLOS Gene

Evolution for GHRLOS Gene

ENSEMBL:
Gene Tree for GHRLOS (if available)
TreeFam:
Gene Tree for GHRLOS (if available)

No data available for Orthologs for GHRLOS Gene

Paralogs for GHRLOS Gene

No data available for Paralogs for GHRLOS Gene

Variants for GHRLOS Gene

Sequence variations from dbSNP and Humsavar for GHRLOS Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs34911341 risk-factor, Metabolic syndrome, susceptibility to, Obesity 10,289,835(+) C/T intron_variant
rs4684677 risk-factor, Obesity 10,286,769(+) T/A intron_variant
rs696217 pathogenic, risk-factor, Obesity, age at onset of, Metabolic syndrome, susceptibility to 10,289,773(+) G/T intron_variant
rs1000183653 -- 10,288,125(+) C/T intron_variant
rs1000408195 -- 10,291,645(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for GHRLOS Gene

Variant ID Type Subtype PubMed ID
dgv762e201 CNV deletion 23290073
esv4117 OTHER complex 18987735
nsv1073204 CNV deletion 25765185
nsv1121603 CNV deletion 24896259
nsv436362 CNV deletion 17901297
nsv436869 CNV insertion 17901297
nsv460420 CNV loss 19166990
nsv508903 CNV insertion 20534489
nsv589650 CNV loss 21841781

Additional Variant Information for GHRLOS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GHRLOS

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for GHRLOS Gene

Disorders for GHRLOS Gene

Additional Disease Information for GHRLOS

No disorders were found for GHRLOS Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GHRLOS Gene

Publications for GHRLOS Gene

  1. Complex organisation and structure of the ghrelin antisense strand gene GHRLOS, a candidate non-coding RNA gene. (PMID: 18954468) Seim I … Chopin LK (BMC molecular biology 2008) 2 3 58
  2. Revised genomic structure of the human ghrelin gene and identification of novel exons, alternative splice variants and natural antisense transcripts. (PMID: 17727735) Seim I … Chopin LK (BMC genomics 2007) 2 3 58

Products for GHRLOS Gene

Sources for GHRLOS Gene

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