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Aliases for GHET1 Gene

Subcategory (RNA class) for GHET1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for GHET1 Gene

  • Gastric Carcinoma Proliferation Enhancing Transcript 1 2 3 5
  • Gastric Carcinoma High Expressed Transcript 1 2 3
  • LncRNA-GHET1 3

External Ids for GHET1 Gene

Previous GeneCards Identifiers for GHET1 Gene

  • GC07U903701
  • GC07P148996
  • GC07P149018
  • GC07P148998
  • GC07P149000
  • GC07P149002
  • GC07P149005
  • GC07P149010
  • GC07P149012
  • GC07P149014
  • GC07P149016

Summaries for GHET1 Gene

Entrez Gene Summary for GHET1 Gene

  • This gene encodes an unspliced long non-coding RNA that has been suggested to promote the proliferation of gastric carcinoma cells and bladder cancer cells. [provided by RefSeq, Dec 2014]

GeneCards Summary for GHET1 Gene

GHET1 (Gastric Carcinoma Proliferation Enhancing Transcript 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with GHET1 include Bladder Cancer and Gastric Cancer.

Additional gene information for GHET1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GHET1 Gene

Genomics for GHET1 Gene

GeneHancer (GH) Regulatory Elements for GHET1 Gene

Promoters and enhancers for GHET1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J148985 Promoter/Enhancer 1.6 Ensembl ENCODE 600.7 -0.4 -426 3.4 SP1 CC2D1A ELF3 ZKSCAN8 MLLT1 CEBPG GTF2F1 CSDE1 ZNF384 ZSCAN21 RNY1 GHET1 GC07M148988 ZNF783 LOC155060 ZNF777 ZNF398 ZNF212 ENSG00000271664 ZNF767P
GH07J149026 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.3 +40.6 40581 3.8 HDGF SP1 CC2D1A ELF3 ZFX MNT NKRF POLR2A ZNF121 GTF2F1 PDIA4 ZNF783 LOC155060 ZNF767P ENSG00000271664 ZNF777 ZNF212 ZNF398 GHET1
GH07J149005 Enhancer 1 Ensembl ENCODE 0.4 +18.4 18437 1.2 CTCF MLLT1 RAD21 EGR1 GLIS2 GMEB1 ZBTB33 ZNF143 REST TRIM22 PDIA4 GHET1
GH07J149007 Enhancer 0.4 ENCODE 0.3 +20.2 20207 0.3 RAD21 CTCF ZNF2 PDIA4 RNU6-650P GHET1
GH07J148992 Enhancer 0.2 Ensembl 0.7 +4.9 4874 0.4 PDIA4 GHET1 GC07P149021
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GHET1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for GHET1 Gene

Genomic Locations for GHET1 Gene
chr7:148,987,527-148,989,432
(GRCh38/hg38)
Size:
1,906 bases
Orientation:
Plus strand

Genomic View for GHET1 Gene

Genes around GHET1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GHET1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GHET1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GHET1 Gene

Proteins for GHET1 Gene

No data available for DME Specific Peptides for GHET1 Gene

Domains & Families for GHET1 Gene

Gene Families for GHET1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GHET1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GHET1 Gene

Function for GHET1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GHET1 Gene

Localization for GHET1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GHET1 gene
Compartment Confidence
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GHET1 Gene

Pathways & Interactions for GHET1 Gene

PathCards logo

SuperPathways for GHET1 Gene

No Data Available

Interacting Proteins for GHET1 Gene

Gene Ontology (GO) - Biological Process for GHET1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GHET1 Gene

Drugs & Compounds for GHET1 Gene

No Compound Related Data Available

Transcripts for GHET1 Gene

mRNA/cDNA for GHET1 Gene

(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for GHET1 Gene

No ASD Table

Relevant External Links for GHET1 Gene

GeneLoc Exon Structure for
GHET1
ECgene alternative splicing isoforms for
GHET1

Expression for GHET1 Gene

NURSA nuclear receptor signaling pathways regulating expression of GHET1 Gene:

GHET1
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GHET1 Gene

Orthologs for GHET1 Gene

Evolution for GHET1 Gene

ENSEMBL:
Gene Tree for GHET1 (if available)
TreeFam:
Gene Tree for GHET1 (if available)

No data available for Orthologs for GHET1 Gene

Paralogs for GHET1 Gene

No data available for Paralogs for GHET1 Gene

Variants for GHET1 Gene

Sequence variations from dbSNP and Humsavar for GHET1 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000809182 -- 148,986,181(+) G/T upstream_transcript_variant
rs1000882778 -- 148,985,871(+) G/A upstream_transcript_variant
rs1001158920 -- 148,989,673(+) T/C downstream_transcript_variant
rs1001427014 -- 148,987,141(+) A/C/G upstream_transcript_variant
rs1001427704 -- 148,989,526(+) A/T downstream_transcript_variant

Additional Variant Information for GHET1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GHET1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for GHET1 Gene

Disorders for GHET1 Gene

MalaCards: The human disease database

(6) MalaCards diseases for GHET1 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
bladder cancer
  • bladder cancer, somatic
gastric cancer
  • gastric cancer, somatic
pancreatic cancer
  • pancreatic carcinoma
hepatocellular carcinoma
  • hcc
colorectal cancer
  • crc
- elite association - COSMIC cancer census association via MalaCards
Search GHET1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for GHET1

genes like me logo Genes that share disorders with GHET1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GHET1 Gene

Publications for GHET1 Gene

  1. Long non-coding RNA GHET1 promotes gastric carcinoma cell proliferation by increasing c-Myc mRNA stability. (PMID: 24397586) Yang F … Fang G (The FEBS journal 2014) 2 3 58
  2. Long noncoding RNA GHET1 in human cancer. (PMID: 30399371) Li J … Cui Y (Clinica chimica acta; international journal of clinical chemistry 2019) 3 58
  3. LncRNA GHET1 predicts poor prognosis in hepatocellular carcinoma and promotes cell proliferation by silencing KLF2. (PMID: 29139562) Jin L … Huang S (Journal of cellular physiology 2018) 3 58
  4. Knockdown of lncRNA GHET1 suppresses cell proliferation, invasion and LATS1/YAP pathway in non small cell lung cancer. (PMID: 29286919) Guan ZB … Zhuo AS (Cancer biomarkers : section A of Disease markers 2018) 3 58
  5. Long non-coding RNA GHET1 promotes human breast cancer cell proliferation, invasion and migration via affecting epithelial mesenchymal transition. (PMID: 29843220) Song R … Hai T (Cancer biomarkers : section A of Disease markers 2018) 3 58

Products for GHET1 Gene

Sources for GHET1 Gene

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