Aliases for GGTLC1 Gene
External Ids for GGTLC1 Gene
Previous HGNC Symbols for GGTLC1 Gene
Previous GeneCards Identifiers for GGTLC1 Gene
This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008]
GeneCards Summary for GGTLC1 Gene
GGTLC1 (Gamma-Glutamyltransferase Light Chain 1) is a Protein Coding gene. Diseases associated with GGTLC1 include Bladder Sarcoma. Among its related pathways are Folate Metabolism and Eicosanoid Synthesis. Gene Ontology (GO) annotations related to this gene include obsolete gamma-glutamyltransferase activity. An important paralog of this gene is GGT1.