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Aliases for GGA1 Gene

Aliases for GGA1 Gene

  • Golgi Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 1 2 3 5
  • Golgi-Localized, Gamma Ear-Containing, ARF-Binding Protein 1 3 4
  • ADP-Ribosylation Factor-Binding Protein GGA1 3
  • ADP-Ribosylation Factor Binding Protein 1 3
  • Gamma-Adaptin Related Protein 1 3
  • Gamma-Adaptin-Related Protein 1 4

External Ids for GGA1 Gene

Previous GeneCards Identifiers for GGA1 Gene

  • GC22P034619
  • GC22P036247
  • GC22P036329
  • GC22P038004
  • GC22P020971

Summaries for GGA1 Gene

Entrez Gene Summary for GGA1 Gene

  • This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for GGA1 Gene

GGA1 (Golgi Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 1) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Vesicle-mediated transport. An important paralog of this gene is GGA3.

UniProtKB/Swiss-Prot for GGA1 Gene

  • Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.

Gene Wiki entry for GGA1 Gene

Additional gene information for GGA1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GGA1 Gene

Genomics for GGA1 Gene

GeneHancer (GH) Regulatory Elements for GGA1 Gene

Promoters and enhancers for GGA1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J037606 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 679 +2.1 2123 5 FEZF1 DMAP1 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC ZNF610 GLIS1 GGA1 DDX17 SH3BP1 EIF3L H1F0 PLA2G6 GC22P037617 PIR36618
GH22J037558 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 26.2 -41.7 -41713 13.7 MLX DMAP1 YY1 SLC30A9 ZNF213 ZNF143 SP3 SSRP1 ZNF610 GLIS1 CDC42EP1 LGALS2 GGA1 ANKRD54 EIF3L IFT27 DDX17 TRIOBP GCAT H1F0
GH22J038174 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 23.6 +571.6 571574 8.7 MLX DMAP1 YBX1 IRF4 YY1 SLC30A9 E2F8 ZNF143 MCM3 SP3 PLA2G6 DDX17 MAFF ENSG00000228274 PRDX3P1 CSNK1E ANKRD54 CBY1 ENSG00000230912 TRIOBP
GH22J037841 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 24.8 +236.3 236334 3.3 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A ZNF2 YY1 SLC30A9 POLR2B ANKRD54 MIR658 GGA1 DDX17 LL22NC01-81G9.3 EIF3L PLA2G6 PIR42346
GH22J037541 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 31 -64.9 -64897 1.8 INSM2 FEZF1 ZNF2 ZNF335 ZNF366 ATF7 FOS IKZF2 ZNF362 SP3 GGA1 LGALS2 PLA2G6 CDC42EP1 SH3BP1 ENSG00000225867 GC22P037518 CARD10 GC22M043058
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around GGA1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the GGA1 gene promoter:

Genomic Locations for GGA1 Gene

Genomic Locations for GGA1 Gene
chr22:37,607,235-37,633,564
(GRCh38/hg38)
Size:
26,330 bases
Orientation:
Plus strand
chr22:38,004,481-38,029,571
(GRCh37/hg19)

Genomic View for GGA1 Gene

Genes around GGA1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GGA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GGA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GGA1 Gene

Proteins for GGA1 Gene

  • Protein details for GGA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UJY5-GGA1_HUMAN
    Recommended name:
    ADP-ribosylation factor-binding protein GGA1
    Protein Accession:
    Q9UJY5
    Secondary Accessions:
    • A8K3D3
    • B0QYR7
    • Q5R3N1
    • Q5TG07
    • Q6IC75
    • Q86YA9
    • Q8NCS6
    • Q9BW94
    • Q9UG00
    • Q9UGW0
    • Q9UGW1

    Protein attributes for GGA1 Gene

    Size:
    639 amino acids
    Molecular mass:
    70384 Da
    Quaternary structure:
    • Monomer. Interacts with NECAP1. Interacts with CNST (By similarity). Interacts with GGA2 and GGA3. Binds to clathrin and activated ARFs, including ARF1 and ARF6. Interacts with RABEP1 and RABGEF1. Interacts with the type-I membrane proteins SORT1, SORL1, LRP3, M6PR/CD-MPR, IGF2R/CI-MPR and BACE1. Binds CCDC91, P200, SYNRG, EPN4, NECAP2 and AFTPH/aftiphilin. Interacts with TSG101 and UBC. Interacts with RNF11.

    Three dimensional structures from OCA and Proteopedia for GGA1 Gene

    Alternative splice isoforms for GGA1 Gene

neXtProt entry for GGA1 Gene

Post-translational modifications for GGA1 Gene

  • Phosphorylated by CK2 and dephosphorylated by PP2A. Phosphorylation of GGA1 allows the internal AC-LL motif to bind the VHS domain and to inhibit the recognition of cargo signals.
  • Ubiquitinated.
  • Ubiquitination at isoforms=2, 3, 4, 6206, isoforms=2, 3, 4, 6198, isoforms=2, 3, 4, 6165, isoforms=3, 4, 6101, and Lys23
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for GGA1 Gene

Domains & Families for GGA1 Gene

Gene Families for GGA1 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UJY5

UniProtKB/Swiss-Prot:

GGA1_HUMAN :
  • The VHS domain functions as a recognition module for sorting signals composed of an acidic cluster followed by two leucines (AC-LL motif).
  • Belongs to the GGA protein family.
Domain:
  • The VHS domain functions as a recognition module for sorting signals composed of an acidic cluster followed by two leucines (AC-LL motif).
  • The GAT domain is responsible for interaction with ARF-GTP, UBC and RABEP1. Required for recruitment to the TGN it prevents ARF-GTP hydrolysis.
  • The unstructured hinge region contains clathrin-binding but no autoinhibitory (AC-LL) motifs.
  • The GAE domain binds accessory proteins regulating GGAs function.
Family:
  • Belongs to the GGA protein family.
genes like me logo Genes that share domains with GGA1: view

Function for GGA1 Gene

Molecular function for GGA1 Gene

UniProtKB/Swiss-Prot Function:
Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.

Phenotypes From GWAS Catalog for GGA1 Gene

Gene Ontology (GO) - Molecular Function for GGA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding IPI 10747089
GO:0030306 ADP-ribosylation factor binding IPI 12668765
GO:0046982 protein heterodimerization activity IMP 12668765
genes like me logo Genes that share ontologies with GGA1: view
genes like me logo Genes that share phenotypes with GGA1: view

Animal Models for GGA1 Gene

MGI Knock Outs for GGA1:
  • Gga1 Gga1<tm1.1(KOMP)Vlcg>

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GGA1

Clone Products

  • Addgene plasmids for GGA1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GGA1 Gene

Localization for GGA1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GGA1 Gene

Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GGA1 gene
Compartment Confidence
nucleus 5
golgi apparatus 5
endosome 5
cytosol 2
lysosome 2
plasma membrane 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
  • Vesicles (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for GGA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005654 nucleoplasm IDA --
GO:0005768 endosome IEA --
GO:0005794 Golgi apparatus TAS 20214818
GO:0010008 endosome membrane IEA,TAS --
genes like me logo Genes that share ontologies with GGA1: view

Pathways & Interactions for GGA1 Gene

genes like me logo Genes that share pathways with GGA1: view

Pathways by source for GGA1 Gene

Gene Ontology (GO) - Biological Process for GGA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport IEA,TAS 20211637
GO:0015031 protein transport IEA --
GO:0016192 vesicle-mediated transport IEA --
GO:0044267 cellular protein metabolic process TAS --
GO:0045732 positive regulation of protein catabolic process IEA --
genes like me logo Genes that share ontologies with GGA1: view

No data available for SIGNOR curated interactions for GGA1 Gene

Drugs & Compounds for GGA1 Gene

(3) Drugs for GGA1 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Guanosine triphosphate Experimental Pharma 0

(1) Additional Compounds for GGA1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with GGA1: view

Transcripts for GGA1 Gene

Unigene Clusters for GGA1 Gene

Golgi-associated, gamma adaptin ear containing, ARF binding protein 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GGA1

Clone Products

  • Addgene plasmids for GGA1

Alternative Splicing Database (ASD) splice patterns (SP) for GGA1 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f · 9g ^ 10a · 10b ^
SP1: - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - - - - - -
SP4: - - - - - - - - - - - - - - - - - - -
SP5: - - - - - - - - - - - - - - -
SP6: - - - - - - - - - - - - -
SP7: - - - - - - - - - - -
SP8: - - - - -
SP9: - - - - - - - - - - - -
SP10:
SP11:
SP12:
SP13:
SP14: - - - - - - - - - - - - - - - - - - -
SP15: - - - - - - - - - -
SP16: - - - - -
SP17: - - - - - - - - - - - - - - - - - - - - -
SP18: - - - - - - - - - - -
SP19: - - - - - - - - - - - - - -
SP20: - - - - - - - - -
SP21: - - -
SP22:
SP23:
SP24: - - - - - - - - - - - - - -
SP25: - - - - - - - - - - -
SP26: - - - - - - - -
SP27: - - - - - - - - -
SP28: - - - - -
SP29:
SP30:
SP31:

ExUns: 11 ^ 12a · 12b · 12c · 12d · 12e · 12f · 12g ^ 13a · 13b ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b · 18c ^ 19a · 19b · 19c ^ 20a · 20b ^ 21a · 21b · 21c ^
SP1: - - - - - -
SP2: - - - - - -
SP3: - - - - - -
SP4: - - - - - - - - -
SP5: -
SP6: -
SP7: -
SP8: - - - - - - - - - - - - - - - - - - - - - -
SP9: -
SP10: - -
SP11: - -
SP12: - - - -
SP13:
SP14:
SP15: -
SP16: -
SP17: - - - - - - - - - - - - - - - - - - - - - - - -
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:
SP24:
SP25:
SP26:
SP27:
SP28:
SP29:
SP30:
SP31:

ExUns: 22a · 22b ^ 23a · 23b · 23c · 23d ^ 24a · 24b ^ 25a · 25b ^ 26a · 26b
SP1: -
SP2: -
SP3: -
SP4: -
SP5:
SP6:
SP7:
SP8: -
SP9:
SP10:
SP11:
SP12:
SP13: - -
SP14:
SP15:
SP16:
SP17: -
SP18:
SP19:
SP20:
SP21:
SP22: -
SP23:
SP24:
SP25:
SP26:
SP27:
SP28:
SP29:
SP30:
SP31:

Relevant External Links for GGA1 Gene

GeneLoc Exon Structure for
GGA1
ECgene alternative splicing isoforms for
GGA1

Expression for GGA1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GGA1 Gene

mRNA differential expression in normal tissues according to GTEx for GGA1 Gene

This gene is overexpressed in Testis (x4.7).

Protein differential expression in normal tissues from HIPED for GGA1 Gene

This gene is overexpressed in Brain (11.5) and Lymph node (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GGA1 Gene



Protein tissue co-expression partners for GGA1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of GGA1 Gene:

GGA1

SOURCE GeneReport for Unigene cluster for GGA1 Gene:

Hs.499158

mRNA Expression by UniProt/SwissProt for GGA1 Gene:

Q9UJY5-GGA1_HUMAN
Tissue specificity: Ubiquitously expressed.

Evidence on tissue expression from TISSUES for GGA1 Gene

  • Nervous system(4.9)
  • Heart(4.2)
  • Liver(4.2)
  • Intestine(2.1)
genes like me logo Genes that share expression patterns with GGA1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for GGA1 Gene

Orthologs for GGA1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for GGA1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GGA1 33
  • 99.15 (n)
cow
(Bos Taurus)
Mammalia GGA1 34
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GGA1 34 33
  • 89.57 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Gga1 16 34 33
  • 88.45 (n)
rat
(Rattus norvegicus)
Mammalia Gga1 33
  • 87.66 (n)
oppossum
(Monodelphis domestica)
Mammalia GGA1 34
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GGA1 34
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC100857525 33
  • 76.8 (n)
-- 34
  • 75 (a)
OneToMany
-- 34
  • 72 (a)
OneToMany
-- 34
  • 72 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia GGA1 34
  • 66 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gga1 33
  • 65.81 (n)
zebrafish
(Danio rerio)
Actinopterygii gga1 34 33
  • 63.93 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011568 33
  • 50.75 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG3002 35
  • 26 (a)
Gga 34
  • 23 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea apt-9 34
  • 22 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes GGA2 34
  • 21 (a)
ManyToMany
GGA1 34
  • 17 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 39 (a)
OneToMany
Species where no ortholog for GGA1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GGA1 Gene

ENSEMBL:
Gene Tree for GGA1 (if available)
TreeFam:
Gene Tree for GGA1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GGA1: view image

Paralogs for GGA1 Gene

Paralogs for GGA1 Gene

(6) SIMAP similar genes for GGA1 Gene using alignment to 12 proteins:

  • GGA1_HUMAN
  • B0QYR5_HUMAN
  • B0QYR6_HUMAN
  • B0QYR8_HUMAN
  • B0QYR9_HUMAN
  • B0QYS0_HUMAN
  • B0QYS1_HUMAN
  • B0QYS2_HUMAN
  • B0QYS3_HUMAN
  • B0QYS4_HUMAN
  • B0QYS5_HUMAN
  • Q6IC75_HUMAN
genes like me logo Genes that share paralogs with GGA1: view

Variants for GGA1 Gene

Sequence variations from dbSNP and Humsavar for GGA1 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs765255006 A breast cancer sample 37,623,432(+) G/A 5_prime_UTR_variant, coding_sequence_variant, missense_variant, non_coding_transcript_variant
VAR_036523 A breast cancer sample p.Pro484Ala
rs1000122470 -- 37,624,649(+) T/C intron_variant
rs1000175141 -- 37,607,516(+) C/A genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000281879 -- 37,608,866(+) G/T 5_prime_UTR_variant, coding_sequence_variant, genic_upstream_transcript_variant, missense_variant, non_coding_transcript_variant, upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for GGA1 Gene

Variant ID Type Subtype PubMed ID
esv2758838 CNV loss 17122850
esv3558150 CNV deletion 23714750
nsv1057617 CNV gain 25217958
nsv1116957 CNV deletion 24896259
nsv471197 CNV loss 18288195
nsv829203 CNV loss 20364138
nsv834191 CNV loss 17160897

Variation tolerance for GGA1 Gene

Residual Variation Intolerance Score: 3.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.94; 36.01% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GGA1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GGA1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GGA1 Gene

Disorders for GGA1 Gene

Additional Disease Information for GGA1

No disorders were found for GGA1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GGA1 Gene

Publications for GGA1 Gene

  1. Intracellular trafficking and secretion of adiponectin is dependent on GGA-coated vesicles. (PMID: 16407204) Xie L … Mora S (The Journal of biological chemistry 2006) 2 3 22 58
  2. Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins. (PMID: 14567678) He X … Tang J (Biochemistry 2003) 3 4 22 58
  3. Phosphorylation-induced conformational changes regulate GGAs 1 and 3 function at the trans-Golgi network. (PMID: 12578827) Ghosh P … Kornfeld S (The Journal of biological chemistry 2003) 3 4 22 58
  4. GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex. (PMID: 10747089) Dell'Angelica EC … Bonifacino JS (The Journal of cell biology 2000) 2 3 4 58
  5. A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome. (PMID: 10747088) Hirst J … Robinson MS (The Journal of cell biology 2000) 2 3 4 58

Products for GGA1 Gene

  • Addgene plasmids for GGA1