Aliases for GFRAL Gene
External Ids for GFRAL Gene
Previous HGNC Symbols for GFRAL Gene
Previous GeneCards Identifiers for GFRAL Gene
GeneCards Summary for GFRAL Gene
GFRAL (GDNF Family Receptor Alpha Like) is a Protein Coding gene.
UniProtKB/Swiss-Prot for GFRAL Gene
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.