Aliases for GDPD5 Gene
External Ids for GDPD5 Gene
Previous GeneCards Identifiers for GDPD5 Gene
Glycerophosphodiester phosphodiesterases (GDPDs; EC 188.8.131.52), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010]
GeneCards Summary for GDPD5 Gene
GDPD5 (Glycerophosphodiester Phosphodiesterase Domain Containing 5) is a Protein Coding gene. Among its related pathways are PI Metabolism and Glycerophospholipid biosynthesis. Gene Ontology (GO) annotations related to this gene include phosphoric diester hydrolase activity and glycerophosphodiester phosphodiesterase activity. An important paralog of this gene is GDPD2.
UniProtKB/Swiss-Prot Summary for GDPD5 Gene
Glycerophosphodiester phosphodiesterase that promotes neurite formation and drives spinal motor neuron differentiation (By similarity). Mediates the cleavage of glycosylphosphatidylinositol (GPI) anchor of target proteins: removes the GPI-anchor of RECK, leading to release RECK from the plasma membrane (By similarity). May contribute to the osmotic regulation of cellular glycerophosphocholine (By similarity).