Aliases for GDPD3 Gene
External Ids for GDPD3 Gene
Previous GeneCards Identifiers for GDPD3 Gene
GeneCards Summary for GDPD3 Gene
GDPD3 (Glycerophosphodiester Phosphodiesterase Domain Containing 3) is a Protein Coding gene. Diseases associated with GDPD3 include Myopathy, Distal, 3 and Schizophrenia 3. Among its related pathways are Acyl chain remodelling of PE and PI Metabolism. Gene Ontology (GO) annotations related to this gene include phosphoric diester hydrolase activity and glycerophosphodiester phosphodiesterase activity. An important paralog of this gene is GDPD1.
UniProtKB/Swiss-Prot Summary for GDPD3 Gene
Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine.