Aliases for GDPD2 Gene
- Glycerophosphodiester Phosphodiesterase Domain Containing 2 2 3 5
- Osteoblast Differentiation Promoting Factor 2 3 4
- Glycerophosphodiester Phosphodiesterase Domain-Containing Protein 2 3 4
- Glycerophosphoinositol Inositolphosphodiesterase GDPD2 3 4
- Glycerophosphodiester Phosphodiesterase 3 3 4
- OBDPF 3 4
- GDE3 3 4
- EC 18.104.22.168 4
External Ids for GDPD2 Gene
Previous GeneCards Identifiers for GDPD2 Gene
This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
GeneCards Summary for GDPD2 Gene
GDPD2 (Glycerophosphodiester Phosphodiesterase Domain Containing 2) is a Protein Coding gene. Diseases associated with GDPD2 include Epidermolysis Bullosa, Junctional, Non-Herlitz Type. Gene Ontology (GO) annotations related to this gene include phosphoric diester hydrolase activity and glycerophosphoinositol inositolphosphodiesterase activity. An important paralog of this gene is GDPD5.
UniProtKB/Swiss-Prot Summary for GDPD2 Gene
Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity).