Aliases for GDNF-AS1 Gene

Subcategory (RNA class) for GDNF-AS1 Gene

lncRNA

Number of RNA Genes sources:

4 / 14

Aliases for GDNF-AS1 Gene

  • GDNF Antisense RNA 1 2 3 5
  • GDNF Antisense RNA 1 (Head To Head) 2 3
  • GDNF Opposite Strand 2 3
  • GDNF Antisense RNA 1 (Non-Protein Coding) 2
  • HSALNG0041258 167
  • HSALNG0041256 167
  • HSALNG0041262 167
  • NONHSAG040216 92
  • NONHSAG040212 92
  • NONHSAG040215 92
  • Lnc-WDR70-7 168
  • GDNF-AS1 2
  • GDNFOS 3

External Ids for GDNF-AS1 Gene

Summaries for GDNF-AS1 Gene

GeneCards Summary for GDNF-AS1 Gene

GDNF-AS1 (GDNF Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with GDNF-AS1 include Astrocytoma.

Additional gene information for GDNF-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GDNF-AS1 Gene

Genomics for GDNF-AS1 Gene

GeneHancer (GH) Regulatory Elements for GDNF-AS1 Gene

Promoters and enhancers for GDNF-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05J037809 Enhancer 1 Ensembl ENCODE 500.7 -0.6 -645 2.1 SP1 JUND FOS EP300 RELA MEF2C TRIM22 BCL11A TCF12 USF1 GDNF-AS1 RF01045-118
GH05J037735 Enhancer 1.3 Ensembl ENCODE dbSUPER 10.9 -72.6 -72588 7.2 EP300 JUND ZNF639 ZNF10 REST ZNF623 TRIM28 MEF2C ZEB1 OSR2 CPLANE1 WDR70 GDNF-AS1 GDNF piR-32810-097 RF00026-859 RNU6-484P
GH05J037874 Enhancer 0.8 Ensembl ENCODE 15.6 +63.8 63806 1.6 JUND FOS ZIC2 BATF MAFK FOSL2 ATF2 JUNB ATF7 CTCF GDNF-AS1 GDNF lnc-WDR70-6
GH05J037888 Enhancer 0.8 Ensembl ENCODE 11.2 +78.0 78007 2.5 FOXA2 GABPA FOS ZBTB33 USF1 JUND TCF7L2 USF2 RXRA MAX GDNF GDNF-AS1 lnc-WDR70-6
GH05J037497 Enhancer 0.8 Ensembl ENCODE 10.8 -316.3 -316288 2.2 CTCF REST KLF4 NFYB FOS SMARCA4 PBX2 RAD21 SMC3 STAT1 GDNF-AS1 GDNF ENSG00000250155 piR-41195-007 piR-38605-010 WDR70
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GDNF-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for GDNF-AS1 Gene

Genomic Locations for GDNF-AS1 Gene
chr5:37,811,589-37,953,827
(GRCh38/hg38)
Size:
142,239 bases
Orientation:
Plus strand
chr5:37,840,540-37,875,901
(GRCh37/hg19)
Size:
35,362 bases
Orientation:
Plus strand

Genomic View for GDNF-AS1 Gene

Genes around GDNF-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GDNF-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GDNF-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GDNF-AS1 Gene

Proteins for GDNF-AS1 Gene

Post-translational modifications for GDNF-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GDNF-AS1 Gene

Domains & Families for GDNF-AS1 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for GDNF-AS1 Gene

Function for GDNF-AS1 Gene

Phenotypes From GWAS Catalog for GDNF-AS1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GDNF-AS1 Gene

Localization for GDNF-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GDNF-AS1 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GDNF-AS1 Gene

Pathways & Interactions for GDNF-AS1 Gene

PathCards logo

SuperPathways for GDNF-AS1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for GDNF-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for GDNF-AS1 Gene

Drugs & Compounds for GDNF-AS1 Gene

No Compound Related Data Available

Transcripts for GDNF-AS1 Gene

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for GDNF-AS1 Gene

No ASD Table

Relevant External Links for GDNF-AS1 Gene

GeneLoc Exon Structure for
GDNF-AS1

Expression for GDNF-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GDNF-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for GDNF-AS1 Gene

This gene is overexpressed in Brain - Cerebellum (x6.4) and Brain - Cerebellar Hemisphere (x6.0).

SOURCE GeneReport for Unigene cluster for GDNF-AS1 Gene:

Hs.536820
genes like me logo Genes that share expression patterns with GDNF-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GDNF-AS1 Gene

Orthologs for GDNF-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for GDNF-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC101059243 30
  • 99.37 (n)
Species where no ortholog for GDNF-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for GDNF-AS1 Gene

ENSEMBL:
Gene Tree for GDNF-AS1 (if available)
TreeFam:
Gene Tree for GDNF-AS1 (if available)

Paralogs for GDNF-AS1 Gene

No data available for Paralogs for GDNF-AS1 Gene

Variants for GDNF-AS1 Gene

Additional dbSNP identifiers (rs#s) for GDNF-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for GDNF-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv1593e212 CNV loss 25503493
esv1949621 CNV deletion 18987734
esv26026 CNV loss 19812545
esv2730091 CNV deletion 23290073
esv3604748 CNV gain 21293372
esv3604752 CNV loss 21293372
esv3604753 CNV gain 21293372
esv3604754 CNV loss 21293372
esv3604755 CNV loss 21293372
nsv597849 CNV gain 21841781
nsv597854 CNV loss 21841781

Additional Variant Information for GDNF-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GDNF-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for GDNF-AS1 Gene

Disorders for GDNF-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for GDNF-AS1 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
astrocytoma
  • astrocytic tumor
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for GDNF-AS1

genes like me logo Genes that share disorders with GDNF-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GDNF-AS1 Gene

Publications for GDNF-AS1 Gene

  1. Identification of novel GDNF isoforms and cis-antisense GDNFOS gene and their regulation in human middle temporal gyrus of Alzheimer disease. (PMID: 22081608) Airavaara M … Liu QR (The Journal of biological chemistry 2011) 2 3 54
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 54

Products for GDNF-AS1 Gene

Sources for GDNF-AS1 Gene