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Aliases for GDNF-AS1 Gene

Subcategory (RNA class) for GDNF-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for GDNF-AS1 Gene

  • GDNF Antisense RNA 1 (Head To Head) 2 3 5
  • GDNF Opposite Strand 2 3
  • GDNF Antisense RNA 1 (Non-Protein Coding) 2
  • GDNF Antisense RNA 1 2
  • GDNFOS 3

External Ids for GDNF-AS1 Gene

Summaries for GDNF-AS1 Gene

GeneCards Summary for GDNF-AS1 Gene

GDNF-AS1 (GDNF Antisense RNA 1 (Head To Head)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for GDNF-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GDNF-AS1 Gene

Genomics for GDNF-AS1 Gene

GeneHancer (GH) Regulatory Elements for GDNF-AS1 Gene

Promoters and enhancers for GDNF-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I037809 Enhancer 1 Ensembl ENCODE 550.8 -0.8 -770 1.9 ZSCAN4 BATF IRF4 ATF7 ETV6 FOS BCLAF1 IKZF2 RUNX3 JUNB GDNF-AS1 GC05M037700 RNU6-484P
GH05I037737 Enhancer 1.3 Ensembl ENCODE dbSUPER 10.9 -71.9 -71925 4.6 PKNOX1 SMAD1 FEZF1 IRF4 ZNF213 ATF7 FOS RUNX3 JUNB TSHZ1 C5orf42 GDNF-AS1 GDNF WDR70 RNU6-484P GC05M037700
GH05I037874 Enhancer 0.6 ENCODE 15.6 +63.8 63817 1.6 CTCF JUNB BATF ZIC2 ATF2 JUND FOS ATF7 IKZF2 GDNF-AS1 GDNF LINC02117
GH05I037888 Enhancer 0.6 ENCODE 11.2 +78.0 78007 2.5 FOXA2 RXRA CEBPB USF2 MAX GABPA FOXA1 YY1 JUND HNF4A GDNF GDNF-AS1 LINC02117
GH05I037785 Enhancer 0.5 dbSUPER 10.8 -23.8 -23765 4 FOSL1 ZNF335 JUND HLF CEBPA FOS BATF GDNF-AS1 GDNF RNU6-484P GC05M037700
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around GDNF-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for GDNF-AS1 Gene

Genomic Locations for GDNF-AS1 Gene
chr5:37,811,589-37,953,827
(GRCh38/hg38)
Size:
142,239 bases
Orientation:
Plus strand
chr5:37,840,540-37,875,901
(GRCh37/hg19)

Genomic View for GDNF-AS1 Gene

Genes around GDNF-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GDNF-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GDNF-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GDNF-AS1 Gene

Proteins for GDNF-AS1 Gene

Post-translational modifications for GDNF-AS1 Gene

No Post-translational modifications

Other Protein References for GDNF-AS1 Gene

No data available for DME Specific Peptides for GDNF-AS1 Gene

Domains & Families for GDNF-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GDNF-AS1 Gene

Function for GDNF-AS1 Gene

Phenotypes From GWAS Catalog for GDNF-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GDNF-AS1 Gene

Localization for GDNF-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GDNF-AS1 Gene

Pathways & Interactions for GDNF-AS1 Gene

SuperPathways for GDNF-AS1 Gene

No Data Available

Interacting Proteins for GDNF-AS1 Gene

Gene Ontology (GO) - Biological Process for GDNF-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GDNF-AS1 Gene

Drugs & Compounds for GDNF-AS1 Gene

No Compound Related Data Available

Transcripts for GDNF-AS1 Gene

mRNA/cDNA for GDNF-AS1 Gene

(4) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GDNF-AS1 Gene

GDNF antisense RNA 1 (head to head):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GDNF-AS1 Gene

No ASD Table

Relevant External Links for GDNF-AS1 Gene

GeneLoc Exon Structure for
GDNF-AS1
ECgene alternative splicing isoforms for
GDNF-AS1

Expression for GDNF-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GDNF-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for GDNF-AS1 Gene

This gene is overexpressed in Brain - Cerebellum (x6.4) and Brain - Cerebellar Hemisphere (x6.0).

SOURCE GeneReport for Unigene cluster for GDNF-AS1 Gene:

Hs.536820
genes like me logo Genes that share expression patterns with GDNF-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GDNF-AS1 Gene

Orthologs for GDNF-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for GDNF-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC101059243 33
  • 99.37 (n)
Species where no ortholog for GDNF-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for GDNF-AS1 Gene

ENSEMBL:
Gene Tree for GDNF-AS1 (if available)
TreeFam:
Gene Tree for GDNF-AS1 (if available)

Paralogs for GDNF-AS1 Gene

No data available for Paralogs for GDNF-AS1 Gene

Variants for GDNF-AS1 Gene

Sequence variations from dbSNP and Humsavar for GDNF-AS1 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs2973033 benign, Hirschsprung Disease, Dominant 37,839,531(+) T/C upstream_transcript_variant
rs554953764 likely-benign, Hirschsprung Disease, Dominant 37,839,693(+) CCGCCGCCGCCGCCGCC/CCGCCGCCGCCGCCGCCGCC/CCGCCGCCGCCGCCGCCGCCGCC upstream_transcript_variant
rs1000064781 -- 37,869,342(+) A/G genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000168867 -- 37,839,978(+) G/A/T upstream_transcript_variant
rs1000230244 -- 37,868,783(+) G/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for GDNF-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv1593e212 CNV loss 25503493
esv1949621 CNV deletion 18987734
esv26026 CNV loss 19812545
esv2730091 CNV deletion 23290073
esv3604748 CNV gain 21293372
esv3604752 CNV loss 21293372
esv3604753 CNV gain 21293372
esv3604754 CNV loss 21293372
esv3604755 CNV loss 21293372
nsv597849 CNV gain 21841781
nsv597854 CNV loss 21841781

Additional Variant Information for GDNF-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GDNF-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for GDNF-AS1 Gene

Disorders for GDNF-AS1 Gene

Additional Disease Information for GDNF-AS1

No disorders were found for GDNF-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GDNF-AS1 Gene

Publications for GDNF-AS1 Gene

  1. Identification of novel GDNF isoforms and cis-antisense GDNFOS gene and their regulation in human middle temporal gyrus of Alzheimer disease. (PMID: 22081608) Airavaara M … Liu QR (The Journal of biological chemistry 2011) 2 3 58
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for GDNF-AS1 Gene

Sources for GDNF-AS1 Gene

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