Aliases for GDE1 Gene
External Ids for GDE1 Gene
Previous GeneCards Identifiers for GDE1 Gene
GeneCards Summary for GDE1 Gene
GDE1 (Glycerophosphodiester Phosphodiesterase 1) is a Protein Coding gene. Diseases associated with GDE1 include Serine Deficiency and Cone-Rod Dystrophy 2. Among its related pathways are PI Metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include phosphoric diester hydrolase activity and glycerophosphoinositol glycerophosphodiesterase activity. An important paralog of this gene is GDPD2.
UniProtKB/Swiss-Prot Summary for GDE1 Gene
Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity).