Aliases for GDA Gene
External Ids for GDA Gene
Previous GeneCards Identifiers for GDA Gene
This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
GeneCards Summary for GDA Gene
GDA (Guanine Deaminase) is a Protein Coding gene. Diseases associated with GDA include Purine-Pyrimidine Metabolic Disorder. Among its related pathways are Thiopurine Pathway, Pharmacokinetics/Pharmacodynamics and Metabolism of nucleotides. Gene Ontology (GO) annotations related to this gene include hydrolase activity and guanine deaminase activity.
UniProtKB/Swiss-Prot Summary for GDA Gene
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.